# wrapper.py
 import os, subprocess, sys
 appdir = os.path.dirname(sys.argv[0])
 subprocess.Popen([
      os.path.join(appdir, "real-script")] + sys.argv[1:])
 sys.exit(0)

setup(
    name="MyApp",
    app=["wrapper.py"],
    options=dict(py2app=(extra_scripts=["real-script.py"])))