Which SNPs for Fibro?

Which SNPs for Fibro?


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joshuazvi1
Message 1 of 4 , Oct 23, 2014
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Hello all,

I have a particularly tough fibromyalgia/chronic fatigue case. My practice partner and I have been working him up for years and have tried almost everything without much help.

One thing we haven't tried is a genetic medicine approach. On patient request we want to start looking into this. I have taken Dr. Lynch's courses and have studied a bit on my own and feel relatively good with methylation pathway but not much else.

I had him run the methylation and detox pathways through genetic genie for a start. MTHFRs look fine (all wide type homozygous). Only homozygous on genie's methylation panel is MTRRA66G and CBS C699T. On genies' detox panel homozygous for CYP2D6 S486T.

Is there any other SNPs in particular you guys look at for fibro? (and yes I know this is an overgeneralization but I'm looking for any leads for him)

Thanks!

Joshua Goldenberg, ND
Bothell, WA


Anne Van Couvering
Message 2 of 4 , Oct 23, 2014
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Run it through Sterlings app - There are more SNPs described on that- I would look at the mitochondrial SNPs on that.

I'm sure you've checked him for Lyme, right?

Anne Vsn Couvering, ND, CNS, LMT
Sag Harbor, NY


Sandra Murphy Cranmer
Message 3 of 4 , Oct 28, 2014
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Fibro unresponsive to treatment, have you ruled out Lyme?
Sandra Murphy, ND
Halifax, NS


Dr. Joshua Goldenberg
Message 4 of 4 , Oct 28, 2014
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Yes we have ruled out lyme. I'll ask him to run it through sterlings app. Thanks all

Joshua Goldenberg, ND
Bothell WA