[PROXY]
EnableProxyLibrary=false
InitProxyFunctions=true
ProxyLibrary=d3d9_hialgo.dll

[GLOBAL]
UsePatchSpeedhackWithoutGraphics=true
UseDefferedRendering=false
IgnoreCreationKit=true
ForceFakeVideocard=false

[PERFORMANCE]
SpeedHack=true
EnableOcclusionCulling=true

[MULTIHEAD]
ForceVideoAdapterIndex=false
VideoAdapterIndex=0

[MEMORY]
ExpandSystemMemoryX64=true
ReduceSystemMemoryUsage=true
DisableDriverMemoryManager=false
DisablePreloadToVRAM=false
EnableUnsafeMemoryHacks=false
ReservedMemorySizeMb=256
VideoMemorySizeMb=3732
EnableCompression=false
AutodetectVideoMemorySize=false

[WINDOW]
ForceBorderless=false
ForceBorderlessFullscreen=false

[ENGINE]
ForceAnisotropicFiltering=false
MaxAnisotropy=16
ForceLodBias=false
LodBias=0.0
AddDisplaySuperSamplingResolutions=false
EnableVSync=false
VSyncSkipNumFrames=0

[LIMITER]
WaitBusyRenderer=false
EnableFPSLimit=false
FPSLimit=60.0

[INPUT]
//shift
KeyCombination=16
//f12
KeyUseEffect=123
//home
KeyFPSLimit=36
//num /       106
KeyShowFPS=106
//print screen
KeyScreenshot=44
//enter
KeyEditor=13
//f4
KeyFreeVRAM=115
//B
KeyBruteForce=66

[ADAPTIVEQUALITY]
Enable=false
Quality=1
DesiredFPS=60.0

[ANTIALIASING]
EnableEdgeAA=false
EnableTemporalAA=false
EnableSubPixelAA=false

[FIX]
FixGameBugs=true
FixParallaxBugs=true
FixParallaxTerrain=false
FixAliasedTextures=true
IgnoreInventory=true
FixTintGamma=true
RemoveBlur=false
FixSubSurfaceScattering=true
FixSkyReflection=true
FixCursorVisibility=true
FixLag=true

[LONGEXPOSURE]
EnableLongExposureMode=false
Time=1.0
BlendMax=0.0

Also skse.ini

[General]
ClearInvalidRegistrations=1
Enablediagnostics=1

[NotPlacebo]
GiveFirstBornToSheson=1

[Memory]
DefaultHeapInitialAllocMB=768
ScrapHeapSizeMB=256

I also use SSME along, I know SKSE replaces it, but just in case. Here are the settings for SSME, I made them identical to skse as far as I understand:

ssme.ini


[Instructions]
; most users will not need to make any changes to this file
; only change NewValue01 and NewValue02 (not NewValue00)
; do not change anything else or SSME will not work
; the recommended values will work well for most users

[Settings]
GiveFirstBornToSheson=1

; replace movaps with movups
Location00=0x004BD832
OldValue00=0x6086290F
NewValue00=0x6086110F

; 1st block
Location01=0x00687E89
; old value  =  256 MB
OldValue01=0x00000200
; new value
; 0x00000200 =  256 MB
; 0x00000280 =  384 MB
; 0x00000300 =  512 MB (recommended)
; 0x00000380 =  640 MB
; 0x00000400 =  768 MB
; 0x00000480 =  896 MB
; 0x00000500 = 1024 MB (1 GB, will probably crash)
NewValue01=0x00000400

; 2nd block
Location02=0x00A4E6BF
; old value  =  256 MB
OldValue02=0x10000000
; new value
; 0x10000000 =  256 MB (recommended)
; 0x18000000 =  384 MB
; 0x20000000 =  512 MB
; 0x28000000 =  640 MB
; 0x30000000 =  768 MB
; 0x38000000 =  896 MB
; 0x40000000 = 1024 MB (1 GB, will probably crash)
NewValue02=0x10000000