.htaccess :

RewriteEngine On
RewriteBase /
RewriteRule ^(media/.*)$ - [L]
RewriteRule ^(admin_media/.*)$ - [L]
RewriteRule ^(flask\.wsgi/.*)$ - [L]
RewriteRule ^(.*)$ flask/flask.wsgi/$1 [QSA,PT,L]

flask.wsgi:

import os, sys

# edit your username below
sys.path.append("/home/headrx/public_html/flask");

sys.path.insert(0, os.path.dirname(__file__))
from myapp import app as application

# make the secret code a little better
application.secret_key = 'secret'