get a session!
session = InstaPy(username=insta_username,
                  password=insta_password,
                  headless_browser=True,
                  disable_image_load=True,
                  multi_logs=True)

# let's go! :>
with smart_run(session):
    # HEY HO LETS GO
    # general settings
    session.set_dont_include(friends)
    session.set_dont_like(dont_likes)
    session.set_ignore_if_contains(ignore_list)
    session.set_ignore_users(ignore_users)
    session.set_simulation(enabled=True)
    session.set_relationship_bounds(enabled=True,
                                    potency_ratio=None,
                                    delimit_by_numbers=True,
                                    max_followers=100000,
                                    max_following=5000,
                                    min_followers=25,
                                    min_following=25,
                                    min_posts=3)

    session.set_skip_users(skip_private=False,
                           skip_no_profile_pic=True,
                           skip_business=True,
                           dont_skip_business_categories=[
                               target_business_categories])

    session.set_user_interact(amount=3, randomize=True, percentage=80,
                              media='Photo')
    session.set_do_like(enabled=True, percentage=90)
    session.set_do_comment(enabled=False, percentage=15)
    session.set_comments(comments, media='Photo')
    session.set_do_follow(enabled=True, percentage=40, times=1)

    # activities

    # FOLLOW+INTERACTION on TARGETED accounts
    """ Select users form a list of a predefined targets...
    """
    number = random.randint(3, 5)
    random_targets = targets

    if len(targets) <= number:
        random_targets = targets

    else:
        random_targets = random.sample(targets, number)

    """ Interact with the chosen targets...
    """
    session.follow_user_followers(random_targets,
                                  amount=random.randint(30, 60),
                                  randomize=True, sleep_delay=600,
                                  interact=True)

    # UNFOLLOW activity
    """ Unfollow nonfollowers after one day...
    """
    session.unfollow_users(amount=random.randint(75, 100),
                           InstapyFollowed=(True, "nonfollowers"),
                           style="FIFO",
                           unfollow_after=24 * 60 * 60, sleep_delay=600)

    """ Unfollow all users followed by InstaPy after one week to keep the
    following-level clean...
    """
    session.unfollow_users(amount=random.randint(75, 100),
                           InstapyFollowed=(True, "all"), style="FIFO",
                           unfollow_after=168 * 60 * 60, sleep_delay=600)

"""
Have fun while optimizing for your purposes, Nuzzo
"""