public class Data
{
   private CollectionViewSource viewSource = new CollectionViewSource();

   public Data()
   {
     var items = new List<Item>();
     // Create 1000 items
     viewSource.Source = items;
   }

   public ICollectionView View => viewSource.View;
}

public class Item
{
   public string Description { get; set; } = "Text here";
   public bool Bool { get; set; }
   public int Value { get; set; }
   public DateTime TimeStamp { get; set; }
   public Test EnumValue { get; set; }
   public static IEnumerable AvailableEnumValues =>
             Enum.GetValues(typeof(Test));
}

<DataGrid ItemsSource="{Binding View}"
 EnableColumnVirtualization="True" EnableRowVirtualization="True"
 VirtualizingPanel.IsContainerVirtualizable="False"
 VirtualizingPanel.IsVirtualizing="True"
 VirtualizingPanel.VirtualizationMode="Recycling"
 VirtualizingPanel.IsVirtualizingWhenGrouping="True"
 VirtualizingStackPanel.CacheLength="2,3"
 VirtualizingStackPanel.CacheLengthUnit="Page"
 VirtualizingStackPanel.ScrollUnit="Item">
  <DataGrid.Columns>
    <DataGridTextColumn Binding="{Binding Description}" Width="100"/>
        <DataGridTextColumn Binding="{Binding Value}" Width="100"/>
        <DataGridCheckBoxColumn Binding="{Binding Bool}" Width="100"/>
        <DataGridComboBoxColumn SelectedItemBinding="{Binding EnumValue}"
            ItemsSource="{x:Static local:Item.AvailableEnumValues}"
            Width="100"/>
        <DataGridTextColumn Binding="{Binding TimeStamp}" Width="100"/>
     <!-- Repeat 5 columns above 5 times -->
  </DataGrid.Columns>
</DataGrid>