var config = {
    map: {
   '*': {
       dataTables: 'EC_Downloads/js/datatables.min',
       buttonsTables: 'EC_Downloads/js/buttons.min',
       buttonsPrintTables: 'EC_Downloads/js/buttons.print.min'
     }
   }
 };

<script>
require(['jquery', 'jquery/ui','dataTables','buttonsTables','buttonsPrintTables'], function($){
    $(document).ready(function($){
        $('#example').DataTable({
            dom: 'Bfrtip',
            buttons: [
            'print'
        ]
        });
    });
});

require(['jquery','jquery/ui','buttonsTables','buttonsPrintTables'], function($){
    $(document).ready(function($){
        alert('Hello');
    });
});
</script>

require(['jquery', 'jquery.dataTables'], function($, DataTable) {

{
        "jquery.dataTables": "Magento_Theme/js/jquery.dataTables.min"
    },