HELP = range(1)

def start(bot, update):
    keyboard = [
                 [InlineKeyboardButton('Help', callback_data='help')]
               ]

    # Create initial message:
    message = 'Welcome.'

    update.message.reply_text(message, reply_markup=InlineKeyboardMarkup(keyboard))

def help(bot, update):

    keyboard = [
                 [InlineKeyboardButton('Help', callback_data='help')]
               ]

    bot.edit_message_text(
        text='Help ... help..',
        chat_id=update.callback_query.message.chat_id,
        message_id=update.callback_query.message.message_id,
        reply_markup=InlineKeyboardMarkup(keyboard)
    )
    bot.answer_callback_query(update.callback_query.id, text='')

def unknown(bot, update):

    message = 'Please press the Help button for more instructions.'

    keyboard = [
                 [InlineKeyboardButton('Help', callback_data='help')]
               ]

    update.message.reply_text(message, reply_markup=InlineKeyboardMarkup(keyboard))



# Create the EventHandler and pass it your bot's token.
updater = Updater(token=config.TELEGRAM_API_TOKEN)

# Get the dispatcher to register handlers:
dispatcher = updater.dispatcher

dispatcher.add_handler(CommandHandler('start', start))
dispatcher.add_handler(CallbackQueryHandler(help, pattern='help'))
dispatcher.add_handler(MessageHandler(Filters.all, unknown))

updater.start_polling()

updater.idle()

sent_message = update.message.reply_text(
    message,
    reply_markup=InlineKeyboardMarkup(keyboard)
)