I am constantly needing to set an IP on a server for some reason.  Most of the time the reason is to verify connectivity.  Here is the commands I use to add and remove the IP.

ip address add 192.168.122.22/24 dev enP1p1s0f0
ip address del 192.168.122.22/24 dev enP1p1s0f0

Here are a couple of things to keep in mind about these commands:

1. If you do note specify the prefix (/24 in this case) to the IP address the default is /32.
2. The interface is brought up automatically.  There is no need to run ifup
3. I believe ifup and ifdown assume there config files (/etc/sysconf/network-scripts/ifcfg-* for RPM based systems).