ECHO OFF
SETLOCAL EnableDelayedExpansion

FOR /f "tokens=*" %%G in ('dir /b /a:d-s-l "%SystemDrive%\Users"') DO (
    IF /I NOT "%%G"=="Public" (

        reg.exe load HKU\XYZ "%SystemDrive%\Users\%%G\NTUser.dat"

        IF NOT ERRORLEVEL 1 (

            call :regchanges XYZ

            reg.exe unload HKU\XYZ
        )
    )
)

FOR /f "tokens=1,2 skip=1" %%G IN ('wmic.exe PATH Win32_UserProfile get loaded^,sid') DO (
    IF /I "%%G"=="True" (
        set sid=%%H

        IF /I "!sid:~0,8!"=="S-1-5-21" (

            call :regchanges !sid!
        )
    )
)

exit /b

:regchanges

REM reg.exe add "HKU\%1\..." /v ... /t ... /d ... /f

reg.exe delete "HKU\%1\SOFTWARE\Microsoft\Windows\CurrentVersion\Run" /v Win10UpgradeMessage /f

REM reg.exe add "HKU\%1\Software\Temp3" /v TempValue /t REG_SZ /d "A sub Test" /f