import pandas as pd
import sqlalchemy

df=pd.read_excel(r"C:Usersmazin1-601.xlsx")

database_username = 'root'
database_password = 'aUtO1115'
database_ip       = '127.0.0.1'
database_name     = 'patenting in psis'
database_connection = sqlalchemy.create_engine('mysql+mysqlconnector://{0}:{1}@{2}/{3}'.
                                               format(database_username, database_password,
                                                      database_ip, database_name), pool_recycle=1, pool_timeout=30).connect()

df.to_sql(con=database_connection, name='sample', if_exists='replace')
database_connection.close()