static readonly char[] invalidFileNameChars = Path.GetInvalidFileNameChars();

// Builds a string out of valid chars
var validFilename = new string(filename.Where(ch => !invalidFileNameChars.Contains(ch)).ToArray());

static readonly char[] invalidFileNameChars = Path.GetInvalidFileNameChars();

// Builds a string out of valid chars and an _ for invalid ones
var validFilename = new string(filename.Select(ch => invalidFileNameChars.Contains(ch) ? '_' : ch).ToArray());

static readonly IList<char> invalidFileNameChars = Path.GetInvalidFileNameChars();

// Builds a string out of valid chars and replaces invalid chars with a unique letter (Moves the Char into the letter range of unicode, starting at "A")
var validFilename = new string(filename.Select(ch => invalidFileNameChars.Contains(ch) ? Convert.ToChar(invalidFileNameChars.IndexOf(ch) + 65) : ch).ToArray());

string file = @"38?/.}[+=n a882 a.a*/|n^%$ ad#(-))";
Array.ForEach(Path.GetInvalidFileNameChars(),
      c => file = file.Replace(c.ToString(), String.Empty));

public static string MakeSafeFilename(string filename, char replaceChar)
{
    foreach (char c in System.IO.Path.GetInvalidFileNameChars())
    {
        filename = filename.Replace(c, replaceChar);
    }
    return filename;
}

static string GetSafeFileName(string name, char replace = '_') {
  char[] invalids = Path.GetInvalidFileNameChars();
  return new string(name.Select(c => invalids.Contains(c) ? replace : c).ToArray());
}

string myCrazyName = "q`w^e!r@t#y$u%i^o&p*a(s)d_f-g+h=j{k}l|z:x"c<v>b?n[m]q\w;e'r,t.y/u";
string safeName = Regex.Replace(
    myCrazyName,
    "W",  /*Matches any nonword character. Equivalent to '[^A-Za-z0-9_]'*/
    "",
    RegexOptions.IgnoreCase);
// safeName == "qwertyuiopasd_fghjklzxcvbnmqwertyu"

static class Utils
{
    public static string MakeFileSystemSafe(this string s)
    {
        return new string(s.Where(IsFileSystemSafe).ToArray());
    }

    public static bool IsFileSystemSafe(char c)
    {
        return !Path.GetInvalidFileNameChars().Contains(c);
    }
}

public static string ReplaceInvalidFileNameChars(this string s, string replacement = "")
{
  return Regex.Replace(s,
    "[" + Regex.Escape(new String(System.IO.Path.GetInvalidPathChars())) + "]",
    replacement, //can even use a replacement string of any length
    RegexOptions.IgnoreCase);
    //not using System.IO.Path.InvalidPathChars (deprecated insecure API)
}

private void textBoxFileName_KeyPress(object sender, KeyPressEventArgs e)
{
   e.Handled = CheckFileNameSafeCharacters(e);
}

/// <summary>
/// This is a good function for making sure that a user who is naming a file uses proper characters
/// </summary>
/// <param name="e"></param>
/// <returns></returns>
internal static bool CheckFileNameSafeCharacters(System.Windows.Forms.KeyPressEventArgs e)
{
    if (e.KeyChar.Equals(24) ||
        e.KeyChar.Equals(3) ||
        e.KeyChar.Equals(22) ||
        e.KeyChar.Equals(26) ||
        e.KeyChar.Equals(25))//Control-X, C, V, Z and Y
            return false;
    if (e.KeyChar.Equals('b'))//backspace
        return false;

    char[] charArray = Path.GetInvalidFileNameChars();
    if (charArray.Contains(e.KeyChar))
       return true;//Stop the character from being entered into the control since it is non-numerical
    else
        return false;
}

<Extension()>
Public Function MakeSafeFileName(FileName As String) As String
    Return FileName.Where(Function(x) Not IO.Path.GetInvalidFileNameChars.Contains(x)).ToArray
End Function

string UnsafeFileName = "salmnas dlajhdla kjha;dmas'lkasn";
string SafeFileName = Convert.ToBase64String(Encoding.UTF8.GetBytes(UnsafeFileName));

UnsafeFileName = Encoding.UTF8.GetString(Convert.FromBase64String(SafeFileName));