string title = "ASTRINGTOTEST";
title.Contains("string");

culture.CompareInfo.IndexOf(paragraph, word, CompareOptions.IgnoreCase) >= 0

string title = "STRING";
bool contains = title.IndexOf("string", StringComparison.OrdinalIgnoreCase) >= 0;

public static class StringExtensions
{
    public static bool Contains(this string source, string toCheck, StringComparison comp)
    {
        return source.IndexOf(toCheck, comp) >= 0;
    }
}

...

string title = "STRING";
bool contains = title.Contains("string", StringComparison.OrdinalIgnoreCase);

string title = "STRING";

if (title.IndexOf("string", 0, StringComparison.CurrentCultureIgnoreCase) != -1)
{
    // The string exists in the original
}

bool contains = Regex.IsMatch("StRiNG to search", "string", RegexOptions.IgnoreCase);

public static bool Contains(this string source, string toCheck, StringComparison comp)
{
    if (string.IsNullOrEmpty(toCheck) || string.IsNullOrEmpty(source))
        return true;

    return source.IndexOf(toCheck, comp) >= 0;
}

string title = "string":
title.ToUpper().Contains("STRING")  // returns true

public static class StringExtensions
{
    /// <summary>
    /// Allows case insensitive checks
    /// </summary>
    public static bool Contains(this string source, string toCheck, StringComparison comp)
    {
        return source.IndexOf(toCheck, comp) >= 0;
    }
}

Regex.IsMatch(file,fileNamestr,RegexOptions.IgnoreCase)

string title = "STRING";
if (title.IndexOf("string", 0, StringComparison.[YourDecision]) != -1)
{
    // The string exists in the original
}

string s="AbcdEf";
if(s.ToLower().Contains("def"))
{
    Console.WriteLine("yes");
}

Dim str As String = "UPPERlower"
Dim b As Boolean = InStr(str, "UpperLower")

string myString = "Hello World";
bool contains = Microsoft.VisualBasic.Strings.InStr(myString, "world");

private static int InternalInStrText(int lStartPos, string sSrc, string sFind)
{
  int num = sSrc == null ? 0 : sSrc.Length;
  if (lStartPos > num || num == 0)
    return -1;
  if (sFind == null || sFind.Length == 0)
    return lStartPos;
  else
    return Utils.GetCultureInfo().CompareInfo.IndexOf(sSrc, sFind, lStartPos, CompareOptions.IgnoreCase | CompareOptions.IgnoreKanaType | CompareOptions.IgnoreWidth);
}

string.Compare("string", "STRING", new System.Globalization.CultureInfo("en-US"), System.Globalization.CompareOptions.IgnoreCase);

/// <summary>
/// Determines whether the source contains the sequence.
/// </summary>
/// <typeparam name="T">The type of the items in the sequences.</typeparam>
/// <param name="sourceEnumerator">The source enumerator.</param>
/// <param name="sequenceEnumerator">The sequence enumerator.</param>
/// <param name="equalityComparer">An equality comparer.</param>
/// <remarks>
/// An empty sequence will return <c>true</c>.
/// The sequence must support <see cref="IEnumerator.Reset"/>
/// if it does not begin the source.
/// </remarks>
/// <returns>
/// <c>true</c> if the source contains the sequence;
/// otherwise <c>false</c>.
/// </returns>
public static bool Contains<T>(
    IEnumerator<T> sourceEnumerator,
    IEnumerator<T> sequenceEnumerator,
    IEqualityComparer<T> equalityComparer)
{
    if (equalityComparer == null)
    {
        equalityComparer = EqualityComparer<T>.Default;
    }

    while (sequenceEnumerator.MoveNext())
    {
        if (sourceEnumerator.MoveNext())
        {
            if (!equalityComparer.Equals(
                sourceEnumerator.Current,
                sequenceEnumerator.Current))
            {
                sequenceEnumerator.Reset();
            }
        }
        else
        {
            return false;
        }
    }

    return true;
}

public static bool Contains<T>(
        this IEnumerable<T> source,
        IEnumerable<T> sequence,
        IEqualityComparer<T> equalityComparer = null)
{
    if (sequence == null)
    {
        throw new ArgumentNullException("sequence");
    }

    using(var sequenceEnumerator = sequence.GetEnumerator())
    using(var sourceEnumerator = source.GetEnumerator())
    {
        return Contains(
            sourceEnumerator,
            sequenceEnumerator,
            equalityComparer);
    }
}

// The optional parameter ensures the generic overload is invoked
// not the string.Contains() implementation.
"testable".Contains("est", EqualityComparer<char>.Default)

using System.Globalization;

public static bool Contains(
         this string source,
         string value,
         CultureInfo culture = null,
         CompareOptions options = CompareOptions.None)
{
    if (value == null)
    {
        throw new ArgumentNullException("value");
    }

    var compareInfo = culture == null ?
            CultureInfo.CurrentCulture.CompareInfo :
            culture.CompareInfo;

    var sourceEnumerator = StringInfo.GetTextElementEnumerator(source);
    var sequenceEnumerator = StringInfo.GetTextElementEnumerator(value);

    while (sequenceEnumerator.MoveNext())
    {
        if (sourceEnumerator.MoveNext())
        {
            if (!(compareInfo.Compare(
                    sourceEnumerator.Current,
                    sequenceEnumerator.Current,
                    options) == 0))
            {
                sequenceEnumerator.Reset();
            }
        }
        else
        {
            return false;
        }
    }

    return true;
}

"testable".Contains("EST", StringComparer.CurrentCultureIgnoreCase)

Regex.IsMatch(title, "string", RegexOptions.IgnoreCase);

public static class StringExtensions
{
    public static bool Contains(this string source, string toCheck, bool bCaseInsensitive )
    {
        return source.IndexOf(toCheck, bCaseInsensitive ? StringComparison.OrdinalIgnoreCase : StringComparison.Ordinal) >= 0;
    }
}

if( "main String substring".Contains("SUBSTRING", true) )
....

var s="Factory Reset";
            var txt="reset";
 int first = s.IndexOf(txt, StringComparison.InvariantCultureIgnoreCase) + txt.Length;
 var subString = s.Substring(first - txt.Length, txt.Length);

if ("strcmpstring1".IndexOf(Convert.ToString("strcmpstring2"), StringComparison.CurrentCultureIgnoreCase) >= 0){return true;}else{return false;}

public static class StringExtension
{
    #region Public Methods

    public static bool ExContains(this string fullText, string value)
    {
        return ExIndexOf(fullText, value) > -1;
    }

    public static bool ExEquals(this string text, string textToCompare)
    {
        return text.Equals(textToCompare, StringComparison.OrdinalIgnoreCase);
    }

    public static bool ExHasAllEquals(this string text, params string[] textArgs)
    {
        for (int index = 0; index < textArgs.Length; index++)
            if (ExEquals(text, textArgs[index]) == false) return false;
        return true;
    }

    public static bool ExHasEquals(this string text, params string[] textArgs)
    {
        for (int index = 0; index < textArgs.Length; index++)
            if (ExEquals(text, textArgs[index])) return true;
        return false;
    }

    public static bool ExHasNoEquals(this string text, params string[] textArgs)
    {
        return ExHasEquals(text, textArgs) == false;
    }

    public static bool ExHasNotAllEquals(this string text, params string[] textArgs)
    {
        for (int index = 0; index < textArgs.Length; index++)
            if (ExEquals(text, textArgs[index])) return false;
        return true;
    }

    /// <summary>
    /// Reports the zero-based index of the first occurrence of the specified string
    /// in the current System.String object using StringComparison.InvariantCultureIgnoreCase.
    /// A parameter specifies the type of search to use for the specified string.
    /// </summary>
    /// <param name="fullText">
    /// The string to search inside.
    /// </param>
    /// <param name="value">
    /// The string to seek.
    /// </param>
    /// <returns>
    /// The index position of the value parameter if that string is found, or -1 if it
    /// is not. If value is System.String.Empty, the return value is 0.
    /// </returns>
    /// <exception cref="ArgumentNullException">
    /// fullText or value is null.
    /// </exception>
    public static int ExIndexOf(this string fullText, string value)
    {
        return fullText.IndexOf(value, StringComparison.OrdinalIgnoreCase);
    }

    public static bool ExNotEquals(this string text, string textToCompare)
    {
        return ExEquals(text, textToCompare) == false;
    }

    #endregion Public Methods
}

title.Contains("string") || title.Contains("string".ToUpper());