$ cat /proc/acpi/wakeup | sort
Device  S-state   Status   Sysfs node
EHC1      S3    *disabled  pci:0000:00:1d.0
EHC2      S3    *disabled  pci:0000:00:1a.0
GLAN      S4    *enabled   pci:0000:08:00.0
.. ,, ..
USB7      S3    *disabled
WLAN      S3    *disabled  pci:0000:03:00.0
XHCI      S3    *disabled  pci:0000:07:00.0

echo EHC1 > /proc/acpi/wakeup
echo EHC2 > /proc/acpi/wakeup
echo XHCI > /proc/acpi/wakeup

sudo sh -c "echo EHC1 > /proc/acpi/wakeup"
sudo sh -c "echo EHC2 > /proc/acpi/wakeup"
sudo sh -c "echo XHCI > /proc/acpi/wakeup"

printf '%sn' '#!/bin/bash' 'exit 0' | sudo tee -a /etc/rc.local
sudo chmod +x /etc/rc.local

#!/bin/bash
echo EHC1 > /proc/acpi/wakeup
echo EHC2 > /proc/acpi/wakeup
echo XHCI > /proc/acpi/wakeup

exit 0

sudo /etc/init.d/rc.local start

sudo systemctl status rc-local

sudo nano /etc/systemd/system/rc-local.service

[Unit]
 Description=/etc/rc.local Compatibility
 ConditionPathExists=/etc/rc.local

[Service]
 Type=forking
 ExecStart=/etc/rc.local start
 TimeoutSec=0
 StandardOutput=tty
 RemainAfterExit=yes
 SysVStartPriority=99

[Install]
 WantedBy=multi-user.target

sudo systemctl start rc-local.service
sudo systemctl status rc-local.service

#! /bin/sh

if [ ! -r /sys/bus/usb/devices/7-2.3/power/wakeup ]; then
    exit 0
fi
case "$1" in
    pre )
    echo disabled > /sys/bus/usb/devices/7-2.3/power/wakeup
;;
esac

#!/bin/bash

# allow only one instance
r=$(pidof -x -o $$ ssmonoff.sh)
set -- $r
if [ "${#@}" -ge 1 ]; then
    echo "Script already running. Exit..."
    exit
fi

dbus-monitor --session "type='signal',interface='org.gnome.ScreenSaver'" | ( while read line; do
    if echo $line | grep "boolean true" &> /dev/null; then
            xinput --set-prop "Dell Premium USB Optical Mouse" "Device Enabled" "0"
            xset dpms force off
    else
            xinput --set-prop "Dell Premium USB Optical Mouse" "Device Enabled" "1"
    fi
done )

for d in `cat wakeup |grep enabled|grep -v PS2K|cut -b -4`; do echo $d >/proc/acpi/wakeup ; done