$CreatedOn = strval(date("Y-m-d H:i:s"));

$dbh = new PDO('odbc:DRIVER=FreeTDS;SERVERNAME=myMssql;DATABASE=' .
$database.';charset=UTF-8', $user, $password);
$dbh->setAttribute(PDO::ATTR_ERRMODE, PDO::ERRMODE_EXCEPTION);

$query='SET TEXTSIZE 9999999';
$stmt=$dbh->prepare($query);
$stmt->execute();
$stmt=null;

$ins = "insert into tbl_Files(ItemTypeID, Link, FileData, CreatedOn)
                values (

                    '{39A5B367-4A7A-473E-8F74-26977CB6DB67}', 'filename.txt', :content, '{$CreatedOn}'

                )";

$stmt = $dbh->prepare($ins);
$filename = "test.txt";
$handle = fopen($filename, "rb");
$contents = fread($handle, filesize($filename));
fclose($handle);

$stmt->bindParam(':content', $contents, PDO::PARAM_LOB);
$stmt->execute();