from flask import Flask
from flask_mail import Mail, Message
import time

app = Flask(__name__)
app.config.from_pyfile('config.cfg')
mail = Mail(app)

@app.route('/mail/')
def index():
   msg = Message('Hello', sender = 'info@MyDomain.com', recipients = ['info@MyDomain.com'], reply_to = 'visitor@HisDomain.com')
   msg.body = 'Hi ' + time.ctime()
   mail.send(msg)
   return "Sent Ok"

if __name__ == "__main__":
    app.run()

<visitor@HisDomain.com> wrote