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- Oral & Injectable Anabolic Steroid Hormones Anastrozole CAS 120511-73-1 Male Supplement With Anti-estrogen Arimidex
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- •Anastrozole
- •Alias :Arimidex ,Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl)1,3-benzenediacetionitrile
- •CAS NO. : 120511-73-1
- •Assay : 98%~102%
- •Appearance : White crystalline powder
- •Active life cycle : 6 hours
- •MF : C17H19N5
- •MW : 293.37
- •Grade : Pharmaceutical Grade
- •Storage: Shading, confined preservation
- •Manufacturer : Hezhong
- •Usage : Anastrozole is a potent non-steroidal aromatase inhibitors , which lead the decrease of plasma level of estrogen, inhibited the growth of breast cancer. For the treatment of advanced breast cancer in postmenopausal women patients.
- Description :
- Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer.
- Many breast cancers also contain aromatase; the importance of tumor-generated estrogens is uncertain. Treatment of breast cancer has included efforts to decrease estrogen levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed progression of tumor growth in some women. Anastrozole is a potent and selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone.
- Application:
- Three azole aromatase inhibitors are potent selective, it can inhibit the cytochrome P-450 dependent aromatase thereby blocking the biosynthesis of estrogen, but estrogen is the main factor that stimulates the growth of breast cancer cells.
- The treatment of breast cancer, especially for those with adjuvant hormone therapy after menopause after recurrence of women with advanced breast cancer.
- Effects :
- Anastrozole is more effective than previous drugs such as tamoxifen and crucially, it has fewer side effects . Anastrozole has been tested for reducing estrogens, including estradiol, in men.
- Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen--gynecomastia, emotional lability and water retention.
- Bone weakness has been associated with anastrozole.
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