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  1. ********************************************************************************
  2. MEME - Motif discovery tool
  3. ********************************************************************************
  4. MEME version 5.0.1 (Release date: Thu Jun 21 11:55:30 2018 -0700)
  5.  
  6. For further information on how to interpret these results or to get
  7. a copy of the MEME software please access http://meme-suite.org .
  8.  
  9. This file may be used as input to the MAST algorithm for searching
  10. sequence databases for matches to groups of motifs. MAST is available
  11. for interactive use and downloading at http://meme-suite.org .
  12. ********************************************************************************
  13.  
  14.  
  15. ********************************************************************************
  16. REFERENCE
  17. ********************************************************************************
  18. If you use this program in your research, please cite:
  19.  
  20. Timothy L. Bailey and Charles Elkan,
  21. "Fitting a mixture model by expectation maximization to discover
  22. motifs in biopolymers", Proceedings of the Second International
  23. Conference on Intelligent Systems for Molecular Biology, pp. 28-36,
  24. AAAI Press, Menlo Park, California, 1994.
  25. ********************************************************************************
  26.  
  27.  
  28. ********************************************************************************
  29. TRAINING SET
  30. ********************************************************************************
  31. PRIMARY SEQUENCES= ciliaryGpcrs_noPKDs.txt
  32. CONTROL SEQUENCES= --none--
  33. ALPHABET= ACGT
  34. Sequence name Weight Length Sequence name Weight Length
  35. ------------- ------ ------ ------------- ------ ------
  36. Kiss1r 1.0000 7129 Mc4r 1.0000 2783
  37. Arl13b 1.0000 53746 Drd1 1.0000 4476
  38. Htr6 1.0000 15817 Mchr1 1.0000 3466
  39. Sstr3 1.0000 12356 Npy2r 1.0000 10607
  40. ********************************************************************************
  41.  
  42. ********************************************************************************
  43. COMMAND LINE SUMMARY
  44. ********************************************************************************
  45. This information can also be useful in the event you wish to report a
  46. problem with the MEME software.
  47.  
  48. command: meme ciliaryGpcrs_noPKDs.txt -dna -oc . -nostatus -time 18000 -mod zoops -nmotifs 25 -minw 6 -maxw 50 -objfun classic -revcomp -markov_order 0
  49.  
  50. model: mod= zoops nmotifs= 25 evt= inf
  51. objective function: em= E-value of product of p-values
  52. starts= E-value of product of p-values
  53. strands: + -
  54. width: minw= 6 maxw= 50
  55. nsites: minsites= 2 maxsites= 8 wnsites= 0.8
  56. theta: spmap= uni spfuzz= 0.5
  57. em: prior= dirichlet b= 0.01 maxiter= 50
  58. distance= 1e-05
  59. trim: wg= 11 ws= 1 endgaps= yes
  60. data: n= 110380 N= 8
  61. sample: seed= 0 hsfrac= 0
  62. searchsize= 100000 norand= no csites= 1000
  63. Letter frequencies in dataset:
  64. A 0.272 C 0.228 G 0.228 T 0.272
  65. Background letter frequencies (from file dataset with add-one prior applied):
  66. A 0.272 C 0.228 G 0.228 T 0.272
  67. Background model order: 0
  68. ********************************************************************************
  69.  
  70.  
  71. ********************************************************************************
  72. MOTIF TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 width = 50 sites = 6 llr = 396 E-value = 5.4e-065
  73. ********************************************************************************
  74. --------------------------------------------------------------------------------
  75. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 Description
  76. --------------------------------------------------------------------------------
  77. Simplified A ::::::::2::::::::::2:::::::::::::::::::2:::::::::3
  78. pos.-specific C 2::::::::::::::::::::::::::2::::::::::::::::::::::
  79. probability G :a:a:a:a:a:a:a:a:a:8:a:a:a:8:a:a:a:8:a:8:a:a:a:a:7
  80. matrix T 8:a:a:a:8:a:a:a:a:a:a:a:a:a:a:a:a:a2a:a:a:a:a:a:a:
  81.  
  82. bits 2.1 * * * * * * * * * * * * * * * * * * * *
  83. 1.9 ******* ********** ******* ******* *** *********
  84. 1.7 ******* ********** ******* ******* *** *********
  85. 1.5 ******* ****************************************
  86. Relative 1.3 *************************************************
  87. Entropy 1.1 **************************************************
  88. (95.3 bits) 0.9 **************************************************
  89. 0.6 **************************************************
  90. 0.4 **************************************************
  91. 0.2 **************************************************
  92. 0.0 --------------------------------------------------
  93.  
  94. Multilevel TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
  95. consensus A
  96. sequence
  97.  
  98. --------------------------------------------------------------------------------
  99.  
  100. --------------------------------------------------------------------------------
  101. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 sites sorted by position p-value
  102. --------------------------------------------------------------------------------
  103. Sequence name Strand Start P-value Site
  104. ------------- ------ ----- --------- --------------------------------------------------
  105. Mchr1 - 1217 6.50e-31 AGGACATTTG TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTG
  106. Kiss1r - 4346 1.42e-30 GCACGAACGT TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTA ATTCCGACTC
  107. Npy2r - 6550 2.62e-30 TGTGTGTATA TGTGTGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG AATGCTAGCA
  108. Arl13b + 13404 3.27e-30 TGTGTGTGTC TGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTC
  109. Htr6 - 4527 2.17e-29 TACACGTGTG TGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGTGTGTGTATGTGTGTGTG TGTACACGCA
  110. Sstr3 + 6567 2.61e-29 TGTGTGTGTA CGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTGTGTGTA CATGCTTTTG
  111. --------------------------------------------------------------------------------
  112.  
  113. --------------------------------------------------------------------------------
  114. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 block diagrams
  115. --------------------------------------------------------------------------------
  116. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  117. ------------- ---------------- -------------
  118. Mchr1 6.5e-31 1216_[-1]_2200
  119. Kiss1r 1.4e-30 4345_[-1]_2734
  120. Npy2r 2.6e-30 6549_[-1]_4008
  121. Arl13b 3.3e-30 13403_[+1]_40293
  122. Htr6 2.2e-29 4526_[-1]_11241
  123. Sstr3 2.6e-29 6566_[+1]_5740
  124. --------------------------------------------------------------------------------
  125.  
  126. --------------------------------------------------------------------------------
  127. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 in BLOCKS format
  128. --------------------------------------------------------------------------------
  129. BL MOTIF TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR width=50 seqs=6
  130. Mchr1 ( 1217) TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1
  131. Kiss1r ( 4346) TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTA 1
  132. Npy2r ( 6550) TGTGTGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1
  133. Arl13b ( 13404) TGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTGTGTGTGTGTGTGTGTGTG 1
  134. Htr6 ( 4527) TGTGTGTGTGTGTGTGTGTATGTGTGTGTGTGTGTGTGTATGTGTGTGTG 1
  135. Sstr3 ( 6567) CGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTGTGTGTA 1
  136. //
  137.  
  138. --------------------------------------------------------------------------------
  139.  
  140. --------------------------------------------------------------------------------
  141. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 position-specific scoring matrix
  142. --------------------------------------------------------------------------------
  143. log-odds matrix: alength= 4 w= 50 n= 109988 bayes= 14.6094 E= 5.4e-065
  144. -923 -45 -923 161
  145. -923 -923 213 -923
  146. -923 -923 -923 187
  147. -923 -923 213 -923
  148. -923 -923 -923 187
  149. -923 -923 213 -923
  150. -923 -923 -923 187
  151. -923 -923 213 -923
  152. -71 -923 -923 161
  153. -923 -923 213 -923
  154. -923 -923 -923 187
  155. -923 -923 213 -923
  156. -923 -923 -923 187
  157. -923 -923 213 -923
  158. -923 -923 -923 187
  159. -923 -923 213 -923
  160. -923 -923 -923 187
  161. -923 -923 213 -923
  162. -923 -923 -923 187
  163. -71 -923 187 -923
  164. -923 -923 -923 187
  165. -923 -923 213 -923
  166. -923 -923 -923 187
  167. -923 -923 213 -923
  168. -923 -923 -923 187
  169. -923 -923 213 -923
  170. -923 -923 -923 187
  171. -923 -45 187 -923
  172. -923 -923 -923 187
  173. -923 -923 213 -923
  174. -923 -923 -923 187
  175. -923 -923 213 -923
  176. -923 -923 -923 187
  177. -923 -923 213 -923
  178. -923 -923 -923 187
  179. -923 -923 187 -71
  180. -923 -923 -923 187
  181. -923 -923 213 -923
  182. -923 -923 -923 187
  183. -71 -923 187 -923
  184. -923 -923 -923 187
  185. -923 -923 213 -923
  186. -923 -923 -923 187
  187. -923 -923 213 -923
  188. -923 -923 -923 187
  189. -923 -923 213 -923
  190. -923 -923 -923 187
  191. -923 -923 213 -923
  192. -923 -923 -923 187
  193. 29 -923 155 -923
  194. --------------------------------------------------------------------------------
  195.  
  196. --------------------------------------------------------------------------------
  197. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 position-specific probability matrix
  198. --------------------------------------------------------------------------------
  199. letter-probability matrix: alength= 4 w= 50 nsites= 6 E= 5.4e-065
  200. 0.000000 0.166667 0.000000 0.833333
  201. 0.000000 0.000000 1.000000 0.000000
  202. 0.000000 0.000000 0.000000 1.000000
  203. 0.000000 0.000000 1.000000 0.000000
  204. 0.000000 0.000000 0.000000 1.000000
  205. 0.000000 0.000000 1.000000 0.000000
  206. 0.000000 0.000000 0.000000 1.000000
  207. 0.000000 0.000000 1.000000 0.000000
  208. 0.166667 0.000000 0.000000 0.833333
  209. 0.000000 0.000000 1.000000 0.000000
  210. 0.000000 0.000000 0.000000 1.000000
  211. 0.000000 0.000000 1.000000 0.000000
  212. 0.000000 0.000000 0.000000 1.000000
  213. 0.000000 0.000000 1.000000 0.000000
  214. 0.000000 0.000000 0.000000 1.000000
  215. 0.000000 0.000000 1.000000 0.000000
  216. 0.000000 0.000000 0.000000 1.000000
  217. 0.000000 0.000000 1.000000 0.000000
  218. 0.000000 0.000000 0.000000 1.000000
  219. 0.166667 0.000000 0.833333 0.000000
  220. 0.000000 0.000000 0.000000 1.000000
  221. 0.000000 0.000000 1.000000 0.000000
  222. 0.000000 0.000000 0.000000 1.000000
  223. 0.000000 0.000000 1.000000 0.000000
  224. 0.000000 0.000000 0.000000 1.000000
  225. 0.000000 0.000000 1.000000 0.000000
  226. 0.000000 0.000000 0.000000 1.000000
  227. 0.000000 0.166667 0.833333 0.000000
  228. 0.000000 0.000000 0.000000 1.000000
  229. 0.000000 0.000000 1.000000 0.000000
  230. 0.000000 0.000000 0.000000 1.000000
  231. 0.000000 0.000000 1.000000 0.000000
  232. 0.000000 0.000000 0.000000 1.000000
  233. 0.000000 0.000000 1.000000 0.000000
  234. 0.000000 0.000000 0.000000 1.000000
  235. 0.000000 0.000000 0.833333 0.166667
  236. 0.000000 0.000000 0.000000 1.000000
  237. 0.000000 0.000000 1.000000 0.000000
  238. 0.000000 0.000000 0.000000 1.000000
  239. 0.166667 0.000000 0.833333 0.000000
  240. 0.000000 0.000000 0.000000 1.000000
  241. 0.000000 0.000000 1.000000 0.000000
  242. 0.000000 0.000000 0.000000 1.000000
  243. 0.000000 0.000000 1.000000 0.000000
  244. 0.000000 0.000000 0.000000 1.000000
  245. 0.000000 0.000000 1.000000 0.000000
  246. 0.000000 0.000000 0.000000 1.000000
  247. 0.000000 0.000000 1.000000 0.000000
  248. 0.000000 0.000000 0.000000 1.000000
  249. 0.333333 0.000000 0.666667 0.000000
  250. --------------------------------------------------------------------------------
  251.  
  252. --------------------------------------------------------------------------------
  253. Motif TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTR MEME-1 regular expression
  254. --------------------------------------------------------------------------------
  255. TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT[GA]
  256. --------------------------------------------------------------------------------
  257.  
  258.  
  259.  
  260.  
  261. Time 653.34 secs.
  262.  
  263. ********************************************************************************
  264.  
  265.  
  266. ********************************************************************************
  267. MOTIF STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 width = 49 sites = 7 llr = 275 E-value = 7.1e-018
  268. ********************************************************************************
  269. --------------------------------------------------------------------------------
  270. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 Description
  271. --------------------------------------------------------------------------------
  272. Simplified A 11:::::4::311::::::1:::3:11:::::111:3:::6:1:1:::1
  273. pos.-specific C 3:::1:1:1::14:3:41:11:4:::1:6:1311:411:3:::11:1::
  274. probability G 41a47:939373317:43739:6:917:4:9:619:4:a:4:9:7:917
  275. matrix T 17:61a:3:7:419:a1634:a:717:a:a:716:619:7:a:9:a:91
  276.  
  277. bits 2.1 * *
  278. 1.9 * * * * * * * * *
  279. 1.7 * * * * * * * * *
  280. 1.5 * ** * * ** * * ** * * ** **
  281. Relative 1.3 * ** * * *** * ** * * ** * ** *** ***
  282. Entropy 1.1 ** ** *** *** * ***** ***** ** ******* ***
  283. (56.7 bits) 0.9 ****** *** *** * ************ ** ************
  284. 0.6 ****** *** ****** ************ ** ************
  285. 0.4 ********** ****** ************* ** ************
  286. 0.2 *************************************************
  287. 0.0 -------------------------------------------------
  288.  
  289. Multilevel GTGTGTGAGTGTCTGTCTGTGTGTGTGTCTGTGTGTGTGTATGTGTGTG
  290. consensus C G G GAGG C GGTG CA G C CA CG
  291. sequence T
  292.  
  293. --------------------------------------------------------------------------------
  294.  
  295. --------------------------------------------------------------------------------
  296. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 sites sorted by position p-value
  297. --------------------------------------------------------------------------------
  298. Sequence name Strand Start P-value Site
  299. ------------- ------ ----- --------- -------------------------------------------------
  300. Arl13b + 13567 2.68e-28 GTGTGTATGT GTGTGTGTGTGTCTGTGTGTGTGTGTGTCTGTGTGTGTGTGTGTGTGTG TCTGTGTGTG
  301. Npy2r + 2783 1.04e-27 CTAGAAGTGT GTGTGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTAGCGC
  302. Htr6 - 3565 3.44e-21 TTAACTTTGT GTGTGTGTGTGTGTGTCTGTGTCTGTGTGTGCACACATGTATGTGTGTG TACATGTGTG
  303. Sstr3 + 6516 2.85e-19 TGAGGAGGGT CTGGCTGGGTAGCTGTGTTCCTGTGAGTGTGTGTGCATGCATGTGTGTG TACGTGTGTG
  304. Kiss1r + 2774 4.43e-18 CAGTGTTATG AAGGGTGGGGACCTGTTGTGGTCAGGGTCTGTGTGTGTGTGTGTGTGGG GGGGGGGGAT
  305. Mchr1 + 2851 9.96e-15 AAGGAAAGGG TGGTTTGACTGGTTCTCGGGGTCTGTATCTGTTGGCTCGCATATATCTT TCTCTCAAGG
  306. Mc4r - 351 1.52e-14 ATCCAACCTC CTGGGTCAGGGAAGCTCCGAGTGATTCTCTCCCAGTCTGTATGCCTGTA GAAGTTGGGA
  307. --------------------------------------------------------------------------------
  308.  
  309. --------------------------------------------------------------------------------
  310. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 block diagrams
  311. --------------------------------------------------------------------------------
  312. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  313. ------------- ---------------- -------------
  314. Arl13b 2.7e-28 13566_[+2]_40131
  315. Npy2r 1e-27 2782_[+2]_7776
  316. Htr6 3.4e-21 3564_[-2]_12204
  317. Sstr3 2.8e-19 6515_[+2]_5792
  318. Kiss1r 4.4e-18 2773_[+2]_4307
  319. Mchr1 1e-14 2850_[+2]_567
  320. Mc4r 1.5e-14 350_[-2]_2384
  321. --------------------------------------------------------------------------------
  322.  
  323. --------------------------------------------------------------------------------
  324. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 in BLOCKS format
  325. --------------------------------------------------------------------------------
  326. BL MOTIF STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG width=49 seqs=7
  327. Arl13b ( 13567) GTGTGTGTGTGTCTGTGTGTGTGTGTGTCTGTGTGTGTGTGTGTGTGTG 1
  328. Npy2r ( 2783) GTGTGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG 1
  329. Htr6 ( 3565) GTGTGTGTGTGTGTGTCTGTGTCTGTGTGTGCACACATGTATGTGTGTG 1
  330. Sstr3 ( 6516) CTGGCTGGGTAGCTGTGTTCCTGTGAGTGTGTGTGCATGCATGTGTGTG 1
  331. Kiss1r ( 2774) AAGGGTGGGGACCTGTTGTGGTCAGGGTCTGTGTGTGTGTGTGTGTGGG 1
  332. Mchr1 ( 2851) TGGTTTGACTGGTTCTCGGGGTCTGTATCTGTTGGCTCGCATATATCTT 1
  333. Mc4r ( 351) CTGGGTCAGGGAAGCTCCGAGTGATTCTCTCCCAGTCTGTATGCCTGTA 1
  334. //
  335.  
  336. --------------------------------------------------------------------------------
  337.  
  338. --------------------------------------------------------------------------------
  339. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 position-specific scoring matrix
  340. --------------------------------------------------------------------------------
  341. log-odds matrix: alength= 4 w= 49 n= 109996 bayes= 13.9396 E= 7.1e-018
  342. -93 33 91 -93
  343. -93 -945 -67 139
  344. -945 -945 213 -945
  345. -945 -945 91 107
  346. -945 -67 165 -93
  347. -945 -945 -945 187
  348. -945 -67 191 -945
  349. 65 -945 33 7
  350. -945 -67 191 -945
  351. -945 -945 33 139
  352. 7 -945 165 -945
  353. -93 -67 33 65
  354. -93 91 33 -93
  355. -945 -945 -67 165
  356. -945 33 165 -945
  357. -945 -945 -945 187
  358. -945 91 91 -93
  359. -945 -67 33 107
  360. -945 -945 165 7
  361. -93 -67 33 65
  362. -945 -67 191 -945
  363. -945 -945 -945 187
  364. -945 91 133 -945
  365. 7 -945 -945 139
  366. -945 -945 191 -93
  367. -93 -945 -67 139
  368. -93 -67 165 -945
  369. -945 -945 -945 187
  370. -945 133 91 -945
  371. -945 -945 -945 187
  372. -945 -67 191 -945
  373. -945 33 -945 139
  374. -93 -67 133 -93
  375. -93 -67 -67 107
  376. -93 -945 191 -945
  377. -945 91 -945 107
  378. 7 -67 91 -93
  379. -945 -67 -945 165
  380. -945 -945 213 -945
  381. -945 33 -945 139
  382. 107 -945 91 -945
  383. -945 -945 -945 187
  384. -93 -945 191 -945
  385. -945 -67 -945 165
  386. -93 -67 165 -945
  387. -945 -945 -945 187
  388. -945 -67 191 -945
  389. -945 -945 -67 165
  390. -93 -945 165 -93
  391. --------------------------------------------------------------------------------
  392.  
  393. --------------------------------------------------------------------------------
  394. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 position-specific probability matrix
  395. --------------------------------------------------------------------------------
  396. letter-probability matrix: alength= 4 w= 49 nsites= 7 E= 7.1e-018
  397. 0.142857 0.285714 0.428571 0.142857
  398. 0.142857 0.000000 0.142857 0.714286
  399. 0.000000 0.000000 1.000000 0.000000
  400. 0.000000 0.000000 0.428571 0.571429
  401. 0.000000 0.142857 0.714286 0.142857
  402. 0.000000 0.000000 0.000000 1.000000
  403. 0.000000 0.142857 0.857143 0.000000
  404. 0.428571 0.000000 0.285714 0.285714
  405. 0.000000 0.142857 0.857143 0.000000
  406. 0.000000 0.000000 0.285714 0.714286
  407. 0.285714 0.000000 0.714286 0.000000
  408. 0.142857 0.142857 0.285714 0.428571
  409. 0.142857 0.428571 0.285714 0.142857
  410. 0.000000 0.000000 0.142857 0.857143
  411. 0.000000 0.285714 0.714286 0.000000
  412. 0.000000 0.000000 0.000000 1.000000
  413. 0.000000 0.428571 0.428571 0.142857
  414. 0.000000 0.142857 0.285714 0.571429
  415. 0.000000 0.000000 0.714286 0.285714
  416. 0.142857 0.142857 0.285714 0.428571
  417. 0.000000 0.142857 0.857143 0.000000
  418. 0.000000 0.000000 0.000000 1.000000
  419. 0.000000 0.428571 0.571429 0.000000
  420. 0.285714 0.000000 0.000000 0.714286
  421. 0.000000 0.000000 0.857143 0.142857
  422. 0.142857 0.000000 0.142857 0.714286
  423. 0.142857 0.142857 0.714286 0.000000
  424. 0.000000 0.000000 0.000000 1.000000
  425. 0.000000 0.571429 0.428571 0.000000
  426. 0.000000 0.000000 0.000000 1.000000
  427. 0.000000 0.142857 0.857143 0.000000
  428. 0.000000 0.285714 0.000000 0.714286
  429. 0.142857 0.142857 0.571429 0.142857
  430. 0.142857 0.142857 0.142857 0.571429
  431. 0.142857 0.000000 0.857143 0.000000
  432. 0.000000 0.428571 0.000000 0.571429
  433. 0.285714 0.142857 0.428571 0.142857
  434. 0.000000 0.142857 0.000000 0.857143
  435. 0.000000 0.000000 1.000000 0.000000
  436. 0.000000 0.285714 0.000000 0.714286
  437. 0.571429 0.000000 0.428571 0.000000
  438. 0.000000 0.000000 0.000000 1.000000
  439. 0.142857 0.000000 0.857143 0.000000
  440. 0.000000 0.142857 0.000000 0.857143
  441. 0.142857 0.142857 0.714286 0.000000
  442. 0.000000 0.000000 0.000000 1.000000
  443. 0.000000 0.142857 0.857143 0.000000
  444. 0.000000 0.000000 0.142857 0.857143
  445. 0.142857 0.000000 0.714286 0.142857
  446. --------------------------------------------------------------------------------
  447.  
  448. --------------------------------------------------------------------------------
  449. Motif STGKGTGDGTGKSTGTSKGKGTSTGTGTSTGTGTGYRTGTRTGTGTGTG MEME-2 regular expression
  450. --------------------------------------------------------------------------------
  451. [GC]TG[TG]GTG[AGT]G[TG][GA][TG][CG]T[GC]T[CG][TG][GT][TG]GT[GC][TA]GTGT[CG]TG[TC]GTG[TC][GA]TG[TC][AG]TGTGTGTG
  452. --------------------------------------------------------------------------------
  453.  
  454.  
  455.  
  456.  
  457. Time 1295.73 secs.
  458.  
  459. ********************************************************************************
  460.  
  461.  
  462. ********************************************************************************
  463. MOTIF CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 width = 41 sites = 6 llr = 188 E-value = 2.7e-006
  464. ********************************************************************************
  465. --------------------------------------------------------------------------------
  466. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 Description
  467. --------------------------------------------------------------------------------
  468. Simplified A :2:3::22:::::2:::::::::::::3:2::::2::::2:
  469. pos.-specific C a:8:5555755285758273a3a582a:5:877:3555837
  470. probability G ::2:::2:::::::::2:2::2:::::23:22233::::::
  471. matrix T :8:7552335582335:827:5:528:528:2272555253
  472.  
  473. bits 2.1 * * * *
  474. 1.9 * * * *
  475. 1.7 * * * *
  476. 1.5 * * * * * * * * * *
  477. Relative 1.3 *** ** ** * * *** ** *
  478. Entropy 1.1 *** ** ***** **** ** ***** ** * **** *
  479. (45.2 bits) 0.9 ****** ***** ******* ***** ***** **** *
  480. 0.6 ****** ******************** ****** **** *
  481. 0.4 ****** *************************** ******
  482. 0.2 *****************************************
  483. 0.0 -----------------------------------------
  484.  
  485. Multilevel CTCTCCCCCCCTCCCCCTCTCTCCCTCTCTCCCTCCCCCTC
  486. consensus ATT TTTT TTT C C T AG GGTTT CT
  487. sequence
  488.  
  489. --------------------------------------------------------------------------------
  490.  
  491. --------------------------------------------------------------------------------
  492. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 sites sorted by position p-value
  493. --------------------------------------------------------------------------------
  494. Sequence name Strand Start P-value Site
  495. ------------- ------ ----- --------- -----------------------------------------
  496. Htr6 + 10638 5.15e-19 TCTCTCCTCT CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC TCCCCCCTCC
  497. Sstr3 + 4654 1.98e-16 CCACCACCCC CTCTTTCTCCTTCCTCCTGCCTCCCTCTGTCCCTGCCTTTT TCTGCATCTC
  498. Kiss1r - 2637 2.66e-15 CCCAGCTCAG CTCACCCCCTCCCACCCCCCCGCCCCCGCTCCCTGCTCCCC AGCCTTTATG
  499. Npy2r + 5336 1.19e-14 CCTCTCCCTC CTCTTCTCTCCTCCCCGTCTCCCTCTCTCACGTGATCCCCC ATCCATCTCT
  500. Mchr1 - 933 4.46e-14 GGAATTTCTC CACACCAACCTTCCCTCTTTCCCCTTCATTCCCTTCTCCTT CAGAGCTAGA
  501. Mc4r - 157 1.29e-13 GACCAGTCTG CTGTTTGCTTTTTTTTCTCTCTCTCTCAGTGCGGCTTTCAC TTTAGTATTC
  502. --------------------------------------------------------------------------------
  503.  
  504. --------------------------------------------------------------------------------
  505. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 block diagrams
  506. --------------------------------------------------------------------------------
  507. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  508. ------------- ---------------- -------------
  509. Htr6 5.1e-19 10637_[+3]_5139
  510. Sstr3 2e-16 4653_[+3]_7662
  511. Kiss1r 2.7e-15 2636_[-3]_4452
  512. Npy2r 1.2e-14 5335_[+3]_5231
  513. Mchr1 4.5e-14 932_[-3]_2493
  514. Mc4r 1.3e-13 156_[-3]_2586
  515. --------------------------------------------------------------------------------
  516.  
  517. --------------------------------------------------------------------------------
  518. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 in BLOCKS format
  519. --------------------------------------------------------------------------------
  520. BL MOTIF CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY width=41 seqs=6
  521. Htr6 ( 10638) CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC 1
  522. Sstr3 ( 4654) CTCTTTCTCCTTCCTCCTGCCTCCCTCTGTCCCTGCCTTTT 1
  523. Kiss1r ( 2637) CTCACCCCCTCCCACCCCCCCGCCCCCGCTCCCTGCTCCCC 1
  524. Npy2r ( 5336) CTCTTCTCTCCTCCCCGTCTCCCTCTCTCACGTGATCCCCC 1
  525. Mchr1 ( 933) CACACCAACCTTCCCTCTTTCCCCTTCATTCCCTTCTCCTT 1
  526. Mc4r ( 157) CTGTTTGCTTTTTTTTCTCTCTCTCTCAGTGCGGCTTTCAC 1
  527. //
  528.  
  529. --------------------------------------------------------------------------------
  530.  
  531. --------------------------------------------------------------------------------
  532. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 position-specific scoring matrix
  533. --------------------------------------------------------------------------------
  534. log-odds matrix: alength= 4 w= 41 n= 110060 bayes= 15.2625 E= 2.7e-006
  535. -923 213 -923 -923
  536. -71 -923 -923 161
  537. -923 187 -45 -923
  538. 29 -923 -923 129
  539. -923 113 -923 88
  540. -923 113 -923 88
  541. -71 113 -45 -71
  542. -71 113 -923 29
  543. -923 155 -923 29
  544. -923 113 -923 88
  545. -923 113 -923 88
  546. -923 -45 -923 161
  547. -923 187 -923 -71
  548. -71 113 -923 29
  549. -923 155 -923 29
  550. -923 113 -923 88
  551. -923 187 -45 -923
  552. -923 -45 -923 161
  553. -923 155 -45 -71
  554. -923 55 -923 129
  555. -923 213 -923 -923
  556. -923 55 -45 88
  557. -923 213 -923 -923
  558. -923 113 -923 88
  559. -923 187 -923 -71
  560. -923 -45 -923 161
  561. -923 213 -923 -923
  562. 29 -923 -45 88
  563. -923 113 55 -71
  564. -71 -923 -923 161
  565. -923 187 -45 -923
  566. -923 155 -45 -71
  567. -923 155 -45 -71
  568. -923 -923 55 129
  569. -71 55 55 -71
  570. -923 113 -923 88
  571. -923 113 -923 88
  572. -923 113 -923 88
  573. -923 187 -923 -71
  574. -71 55 -923 88
  575. -923 155 -923 29
  576. --------------------------------------------------------------------------------
  577.  
  578. --------------------------------------------------------------------------------
  579. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 position-specific probability matrix
  580. --------------------------------------------------------------------------------
  581. letter-probability matrix: alength= 4 w= 41 nsites= 6 E= 2.7e-006
  582. 0.000000 1.000000 0.000000 0.000000
  583. 0.166667 0.000000 0.000000 0.833333
  584. 0.000000 0.833333 0.166667 0.000000
  585. 0.333333 0.000000 0.000000 0.666667
  586. 0.000000 0.500000 0.000000 0.500000
  587. 0.000000 0.500000 0.000000 0.500000
  588. 0.166667 0.500000 0.166667 0.166667
  589. 0.166667 0.500000 0.000000 0.333333
  590. 0.000000 0.666667 0.000000 0.333333
  591. 0.000000 0.500000 0.000000 0.500000
  592. 0.000000 0.500000 0.000000 0.500000
  593. 0.000000 0.166667 0.000000 0.833333
  594. 0.000000 0.833333 0.000000 0.166667
  595. 0.166667 0.500000 0.000000 0.333333
  596. 0.000000 0.666667 0.000000 0.333333
  597. 0.000000 0.500000 0.000000 0.500000
  598. 0.000000 0.833333 0.166667 0.000000
  599. 0.000000 0.166667 0.000000 0.833333
  600. 0.000000 0.666667 0.166667 0.166667
  601. 0.000000 0.333333 0.000000 0.666667
  602. 0.000000 1.000000 0.000000 0.000000
  603. 0.000000 0.333333 0.166667 0.500000
  604. 0.000000 1.000000 0.000000 0.000000
  605. 0.000000 0.500000 0.000000 0.500000
  606. 0.000000 0.833333 0.000000 0.166667
  607. 0.000000 0.166667 0.000000 0.833333
  608. 0.000000 1.000000 0.000000 0.000000
  609. 0.333333 0.000000 0.166667 0.500000
  610. 0.000000 0.500000 0.333333 0.166667
  611. 0.166667 0.000000 0.000000 0.833333
  612. 0.000000 0.833333 0.166667 0.000000
  613. 0.000000 0.666667 0.166667 0.166667
  614. 0.000000 0.666667 0.166667 0.166667
  615. 0.000000 0.000000 0.333333 0.666667
  616. 0.166667 0.333333 0.333333 0.166667
  617. 0.000000 0.500000 0.000000 0.500000
  618. 0.000000 0.500000 0.000000 0.500000
  619. 0.000000 0.500000 0.000000 0.500000
  620. 0.000000 0.833333 0.000000 0.166667
  621. 0.166667 0.333333 0.000000 0.500000
  622. 0.000000 0.666667 0.000000 0.333333
  623. --------------------------------------------------------------------------------
  624.  
  625. --------------------------------------------------------------------------------
  626. Motif CTCWYYCYYYYTCYYYCTCYCYCYCTCWSTCCCKNYYYCYY MEME-3 regular expression
  627. --------------------------------------------------------------------------------
  628. CTC[TA][CT][CT]C[CT][CT][CT][CT]TC[CT][CT][CT]CTC[TC]C[TC]C[CT]CTC[TA][CG]TCCC[TG][CG][CT][CT][CT]C[TC][CT]
  629. --------------------------------------------------------------------------------
  630.  
  631.  
  632.  
  633.  
  634. Time 1930.92 secs.
  635.  
  636. ********************************************************************************
  637.  
  638.  
  639. ********************************************************************************
  640. MOTIF RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 width = 40 sites = 2 llr = 103 E-value = 9.0e-006
  641. ********************************************************************************
  642. --------------------------------------------------------------------------------
  643. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 Description
  644. --------------------------------------------------------------------------------
  645. Simplified A 5a:a:a::::::::::::::5::::::::::::::5:aa:
  646. pos.-specific C ::::a:::::::a:a:::::::5aa:::a:::aa:::::5
  647. probability G 5:5:::aaa:::::::a:a::a::::aa::a::::5a:::
  648. matrix T ::5::::::aaa:a:a:a:a5:5::a:::a:a::a::::5
  649.  
  650. bits 2.1 * *** * * * * * ** *** * ** *
  651. 1.9 * ***************** * ************ ***
  652. 1.7 * ***************** * ************ ***
  653. 1.5 * ***************** * ************ ***
  654. Relative 1.3 * ***************** * ************ ***
  655. Entropy 1.1 ******************** *******************
  656. (74.4 bits) 0.9 ****************************************
  657. 0.6 ****************************************
  658. 0.4 ****************************************
  659. 0.2 ****************************************
  660. 0.0 ----------------------------------------
  661.  
  662. Multilevel AAGACAGGGTTTCTCTGTGTAGCCCTGGCTGTCCTAGAAC
  663. consensus G T T T G T
  664. sequence
  665.  
  666. --------------------------------------------------------------------------------
  667.  
  668. --------------------------------------------------------------------------------
  669. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 sites sorted by position p-value
  670. --------------------------------------------------------------------------------
  671. Sequence name Strand Start P-value Site
  672. ------------- ------ ----- --------- ----------------------------------------
  673. Htr6 + 8302 1.77e-23 CTTTCCCCCT GATACAGGGTTTCTCTGTGTAGTCCTGGCTGTCCTGGAAC TAACTCTGTA
  674. Kiss1r + 5948 3.18e-23 TTGTTTTTTC AAGACAGGGTTTCTCTGTGTTGCCCTGGCTGTCCTAGAAT TCACTTTGCA
  675. --------------------------------------------------------------------------------
  676.  
  677. --------------------------------------------------------------------------------
  678. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 block diagrams
  679. --------------------------------------------------------------------------------
  680. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  681. ------------- ---------------- -------------
  682. Htr6 1.8e-23 8301_[+4]_7476
  683. Kiss1r 3.2e-23 5947_[+4]_1142
  684. --------------------------------------------------------------------------------
  685.  
  686. --------------------------------------------------------------------------------
  687. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 in BLOCKS format
  688. --------------------------------------------------------------------------------
  689. BL MOTIF RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY width=40 seqs=2
  690. Htr6 ( 8302) GATACAGGGTTTCTCTGTGTAGTCCTGGCTGTCCTGGAAC 1
  691. Kiss1r ( 5948) AAGACAGGGTTTCTCTGTGTTGCCCTGGCTGTCCTAGAAT 1
  692. //
  693.  
  694. --------------------------------------------------------------------------------
  695.  
  696. --------------------------------------------------------------------------------
  697. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 position-specific scoring matrix
  698. --------------------------------------------------------------------------------
  699. log-odds matrix: alength= 4 w= 40 n= 110068 bayes= 14.163 E= 9.0e-006
  700. 87 -765 113 -765
  701. 187 -765 -765 -765
  702. -765 -765 113 87
  703. 187 -765 -765 -765
  704. -765 213 -765 -765
  705. 187 -765 -765 -765
  706. -765 -765 213 -765
  707. -765 -765 213 -765
  708. -765 -765 213 -765
  709. -765 -765 -765 187
  710. -765 -765 -765 187
  711. -765 -765 -765 187
  712. -765 213 -765 -765
  713. -765 -765 -765 187
  714. -765 213 -765 -765
  715. -765 -765 -765 187
  716. -765 -765 213 -765
  717. -765 -765 -765 187
  718. -765 -765 213 -765
  719. -765 -765 -765 187
  720. 87 -765 -765 87
  721. -765 -765 213 -765
  722. -765 113 -765 87
  723. -765 213 -765 -765
  724. -765 213 -765 -765
  725. -765 -765 -765 187
  726. -765 -765 213 -765
  727. -765 -765 213 -765
  728. -765 213 -765 -765
  729. -765 -765 -765 187
  730. -765 -765 213 -765
  731. -765 -765 -765 187
  732. -765 213 -765 -765
  733. -765 213 -765 -765
  734. -765 -765 -765 187
  735. 87 -765 113 -765
  736. -765 -765 213 -765
  737. 187 -765 -765 -765
  738. 187 -765 -765 -765
  739. -765 113 -765 87
  740. --------------------------------------------------------------------------------
  741.  
  742. --------------------------------------------------------------------------------
  743. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 position-specific probability matrix
  744. --------------------------------------------------------------------------------
  745. letter-probability matrix: alength= 4 w= 40 nsites= 2 E= 9.0e-006
  746. 0.500000 0.000000 0.500000 0.000000
  747. 1.000000 0.000000 0.000000 0.000000
  748. 0.000000 0.000000 0.500000 0.500000
  749. 1.000000 0.000000 0.000000 0.000000
  750. 0.000000 1.000000 0.000000 0.000000
  751. 1.000000 0.000000 0.000000 0.000000
  752. 0.000000 0.000000 1.000000 0.000000
  753. 0.000000 0.000000 1.000000 0.000000
  754. 0.000000 0.000000 1.000000 0.000000
  755. 0.000000 0.000000 0.000000 1.000000
  756. 0.000000 0.000000 0.000000 1.000000
  757. 0.000000 0.000000 0.000000 1.000000
  758. 0.000000 1.000000 0.000000 0.000000
  759. 0.000000 0.000000 0.000000 1.000000
  760. 0.000000 1.000000 0.000000 0.000000
  761. 0.000000 0.000000 0.000000 1.000000
  762. 0.000000 0.000000 1.000000 0.000000
  763. 0.000000 0.000000 0.000000 1.000000
  764. 0.000000 0.000000 1.000000 0.000000
  765. 0.000000 0.000000 0.000000 1.000000
  766. 0.500000 0.000000 0.000000 0.500000
  767. 0.000000 0.000000 1.000000 0.000000
  768. 0.000000 0.500000 0.000000 0.500000
  769. 0.000000 1.000000 0.000000 0.000000
  770. 0.000000 1.000000 0.000000 0.000000
  771. 0.000000 0.000000 0.000000 1.000000
  772. 0.000000 0.000000 1.000000 0.000000
  773. 0.000000 0.000000 1.000000 0.000000
  774. 0.000000 1.000000 0.000000 0.000000
  775. 0.000000 0.000000 0.000000 1.000000
  776. 0.000000 0.000000 1.000000 0.000000
  777. 0.000000 0.000000 0.000000 1.000000
  778. 0.000000 1.000000 0.000000 0.000000
  779. 0.000000 1.000000 0.000000 0.000000
  780. 0.000000 0.000000 0.000000 1.000000
  781. 0.500000 0.000000 0.500000 0.000000
  782. 0.000000 0.000000 1.000000 0.000000
  783. 1.000000 0.000000 0.000000 0.000000
  784. 1.000000 0.000000 0.000000 0.000000
  785. 0.000000 0.500000 0.000000 0.500000
  786. --------------------------------------------------------------------------------
  787.  
  788. --------------------------------------------------------------------------------
  789. Motif RAKACAGGGTTTCTCTGTGTWGYCCTGGCTGTCCTRGAAY MEME-4 regular expression
  790. --------------------------------------------------------------------------------
  791. [AG]A[GT]ACAGGGTTTCTCTGTGT[AT]G[CT]CCTGGCTGTCCT[AG]GAA[CT]
  792. --------------------------------------------------------------------------------
  793.  
  794.  
  795.  
  796.  
  797. Time 2557.09 secs.
  798.  
  799. ********************************************************************************
  800.  
  801.  
  802. ********************************************************************************
  803. MOTIF BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 width = 49 sites = 4 llr = 179 E-value = 2.1e-005
  804. ********************************************************************************
  805. --------------------------------------------------------------------------------
  806. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 Description
  807. --------------------------------------------------------------------------------
  808. Simplified A :::3::3:::::3:3::5::::::::3:::3:::::3:3:::3:::8::
  809. pos.-specific C 3:::55:583:3::333:5:8::5:5533a::a:::335aa33:a5:38
  810. probability G 5:a8:553:8:88:38355:3:::a::8:::a::aa533::5:::::33
  811. matrix T 3a::5:333:a::a3:5::a:aa5:53:8:8::a:::5:::35a:535:
  812.  
  813. bits 2.1 * * * ** ** ** *
  814. 1.9 ** * * * ** * * ***** ** **
  815. 1.7 ** * * * ** * * ***** ** **
  816. 1.5 ** * * * ** * * ***** ** **
  817. Relative 1.3 *** ****** * **** * * * ***** ** ** *
  818. Entropy 1.1 ***** ****** * ********* ********* ** **** *
  819. (64.5 bits) 0.9 ***** ****** * ********* ********* ** **** *
  820. 0.6 ****** ******* * ********* ********** **** **** *
  821. 0.4 ************** **********************************
  822. 0.2 ************** **********************************
  823. 0.0 -------------------------------------------------
  824.  
  825. Multilevel GTGGCCGCCGTGGTAGTACTCTTCGCCGTCTGCTGGGTCCCGTTCCATC
  826. consensus C ATGAGTC CA CCCGG G T TACC A ACA CA TTCG
  827. sequence T TT G G T CGG TC G
  828. T
  829. --------------------------------------------------------------------------------
  830.  
  831. --------------------------------------------------------------------------------
  832. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 sites sorted by position p-value
  833. --------------------------------------------------------------------------------
  834. Sequence name Strand Start P-value Site
  835. ------------- ------ ----- --------- -------------------------------------------------
  836. Sstr3 + 9626 9.06e-23 CACACGCATG GTGGTGGCCGTGGTGGCACTCTTCGTCCTCTGCTGGATGCCTTTCTATC TGCTCAACAT
  837. Kiss1r + 4647 4.70e-22 CTCCCGGCTG GTGGCCGCTGTCGTCCTGCTCTTCGCCGCCTGCTGGGGCCCGATCCAGC TGTTCCTGGT
  838. Npy2r + 8331 6.09e-20 GACCAAAATG CTGGTGTGCGTGGTAGTGGTGTTTGCAGTCAGCTGGCTACCCCTCCACG CCTTCCAACT
  839. Mc4r + 1186 6.82e-20 GGCGATTACC TTGACCATCCTGATTGGAGTCTTTGTTGTCTGCTGGGCCCCGTTCTTTC TCCATTTACT
  840. --------------------------------------------------------------------------------
  841.  
  842. --------------------------------------------------------------------------------
  843. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 block diagrams
  844. --------------------------------------------------------------------------------
  845. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  846. ------------- ---------------- -------------
  847. Sstr3 9.1e-23 9625_[+5]_2682
  848. Kiss1r 4.7e-22 4646_[+5]_2434
  849. Npy2r 6.1e-20 8330_[+5]_2228
  850. Mc4r 6.8e-20 1185_[+5]_1549
  851. --------------------------------------------------------------------------------
  852.  
  853. --------------------------------------------------------------------------------
  854. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 in BLOCKS format
  855. --------------------------------------------------------------------------------
  856. BL MOTIF BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC width=49 seqs=4
  857. Sstr3 ( 9626) GTGGTGGCCGTGGTGGCACTCTTCGTCCTCTGCTGGATGCCTTTCTATC 1
  858. Kiss1r ( 4647) GTGGCCGCTGTCGTCCTGCTCTTCGCCGCCTGCTGGGGCCCGATCCAGC 1
  859. Npy2r ( 8331) CTGGTGTGCGTGGTAGTGGTGTTTGCAGTCAGCTGGCTACCCCTCCACG 1
  860. Mc4r ( 1186) TTGACCATCCTGATTGGAGTCTTTGTTGTCTGCTGGGCCCCGTTCTTTC 1
  861. //
  862.  
  863. --------------------------------------------------------------------------------
  864.  
  865. --------------------------------------------------------------------------------
  866. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 position-specific scoring matrix
  867. --------------------------------------------------------------------------------
  868. log-odds matrix: alength= 4 w= 49 n= 109996 bayes= 14.0689 E= 2.1e-005
  869. -865 14 113 -12
  870. -865 -865 -865 187
  871. -865 -865 213 -865
  872. -12 -865 172 -865
  873. -865 113 -865 87
  874. -865 113 113 -865
  875. -12 -865 113 -12
  876. -865 113 14 -12
  877. -865 172 -865 -12
  878. -865 14 172 -865
  879. -865 -865 -865 187
  880. -865 14 172 -865
  881. -12 -865 172 -865
  882. -865 -865 -865 187
  883. -12 14 14 -12
  884. -865 14 172 -865
  885. -865 14 14 87
  886. 87 -865 113 -865
  887. -865 113 113 -865
  888. -865 -865 -865 187
  889. -865 172 14 -865
  890. -865 -865 -865 187
  891. -865 -865 -865 187
  892. -865 113 -865 87
  893. -865 -865 213 -865
  894. -865 113 -865 87
  895. -12 113 -865 -12
  896. -865 14 172 -865
  897. -865 14 -865 146
  898. -865 213 -865 -865
  899. -12 -865 -865 146
  900. -865 -865 213 -865
  901. -865 213 -865 -865
  902. -865 -865 -865 187
  903. -865 -865 213 -865
  904. -865 -865 213 -865
  905. -12 14 113 -865
  906. -865 14 14 87
  907. -12 113 14 -865
  908. -865 213 -865 -865
  909. -865 213 -865 -865
  910. -865 14 113 -12
  911. -12 14 -865 87
  912. -865 -865 -865 187
  913. -865 213 -865 -865
  914. -865 113 -865 87
  915. 146 -865 -865 -12
  916. -865 14 14 87
  917. -865 172 14 -865
  918. --------------------------------------------------------------------------------
  919.  
  920. --------------------------------------------------------------------------------
  921. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 position-specific probability matrix
  922. --------------------------------------------------------------------------------
  923. letter-probability matrix: alength= 4 w= 49 nsites= 4 E= 2.1e-005
  924. 0.000000 0.250000 0.500000 0.250000
  925. 0.000000 0.000000 0.000000 1.000000
  926. 0.000000 0.000000 1.000000 0.000000
  927. 0.250000 0.000000 0.750000 0.000000
  928. 0.000000 0.500000 0.000000 0.500000
  929. 0.000000 0.500000 0.500000 0.000000
  930. 0.250000 0.000000 0.500000 0.250000
  931. 0.000000 0.500000 0.250000 0.250000
  932. 0.000000 0.750000 0.000000 0.250000
  933. 0.000000 0.250000 0.750000 0.000000
  934. 0.000000 0.000000 0.000000 1.000000
  935. 0.000000 0.250000 0.750000 0.000000
  936. 0.250000 0.000000 0.750000 0.000000
  937. 0.000000 0.000000 0.000000 1.000000
  938. 0.250000 0.250000 0.250000 0.250000
  939. 0.000000 0.250000 0.750000 0.000000
  940. 0.000000 0.250000 0.250000 0.500000
  941. 0.500000 0.000000 0.500000 0.000000
  942. 0.000000 0.500000 0.500000 0.000000
  943. 0.000000 0.000000 0.000000 1.000000
  944. 0.000000 0.750000 0.250000 0.000000
  945. 0.000000 0.000000 0.000000 1.000000
  946. 0.000000 0.000000 0.000000 1.000000
  947. 0.000000 0.500000 0.000000 0.500000
  948. 0.000000 0.000000 1.000000 0.000000
  949. 0.000000 0.500000 0.000000 0.500000
  950. 0.250000 0.500000 0.000000 0.250000
  951. 0.000000 0.250000 0.750000 0.000000
  952. 0.000000 0.250000 0.000000 0.750000
  953. 0.000000 1.000000 0.000000 0.000000
  954. 0.250000 0.000000 0.000000 0.750000
  955. 0.000000 0.000000 1.000000 0.000000
  956. 0.000000 1.000000 0.000000 0.000000
  957. 0.000000 0.000000 0.000000 1.000000
  958. 0.000000 0.000000 1.000000 0.000000
  959. 0.000000 0.000000 1.000000 0.000000
  960. 0.250000 0.250000 0.500000 0.000000
  961. 0.000000 0.250000 0.250000 0.500000
  962. 0.250000 0.500000 0.250000 0.000000
  963. 0.000000 1.000000 0.000000 0.000000
  964. 0.000000 1.000000 0.000000 0.000000
  965. 0.000000 0.250000 0.500000 0.250000
  966. 0.250000 0.250000 0.000000 0.500000
  967. 0.000000 0.000000 0.000000 1.000000
  968. 0.000000 1.000000 0.000000 0.000000
  969. 0.000000 0.500000 0.000000 0.500000
  970. 0.750000 0.000000 0.000000 0.250000
  971. 0.000000 0.250000 0.250000 0.500000
  972. 0.000000 0.750000 0.250000 0.000000
  973. --------------------------------------------------------------------------------
  974.  
  975. --------------------------------------------------------------------------------
  976. Motif BTGGYSDBCGTGGTNGBRSTCTTYGYHGTCTGCTGGVBVCCBHTCYABC MEME-5 regular expression
  977. --------------------------------------------------------------------------------
  978. [GCT]TG[GA][CT][CG][GAT][CGT][CT][GC]T[GC][GA]T[ACGT][GC][TCG][AG][CG]T[CG]TT[CT]G[CT][CAT][GC][TC]C[TA]GCTGG[GAC][TCG][CAG]CC[GCT][TAC]TC[CT][AT][TCG][CG]
  979. --------------------------------------------------------------------------------
  980.  
  981.  
  982.  
  983.  
  984. Time 3180.74 secs.
  985.  
  986. ********************************************************************************
  987.  
  988.  
  989. ********************************************************************************
  990. MOTIF CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 width = 50 sites = 4 llr = 205 E-value = 1.9e-004
  991. ********************************************************************************
  992. --------------------------------------------------------------------------------
  993. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 Description
  994. --------------------------------------------------------------------------------
  995. Simplified A :::3::88:a::a3:3a::::::::85::3:::83::8::::3:55::::
  996. pos.-specific C 8:8::33:3:38:388::::a:8::3:a85a:3338a3:a3a3a5:5aaa
  997. probability G ::3:a8::8:83:3:::a:5::3::::::3::8:5::::::::::35:::
  998. matrix T 3a:8:::3:::::33:::a5:a:aa:5:3::a:::3::a:8:5::3::::
  999.  
  1000. bits 2.1 * * * * * * * * * ***
  1001. 1.9 * * * * *** ** ** * ** * ** * * ***
  1002. 1.7 * * * * *** ** ** * ** * ** * * ***
  1003. 1.5 * * * * *** ** ** * ** * ** * * ***
  1004. Relative 1.3 *** ** ***** ***** ***** ** *** ** ** * * ***
  1005. Entropy 1.1 ************* ************ ** **** ******* ** ****
  1006. (73.8 bits) 0.9 ************* *************** **** ******* ** ****
  1007. 0.6 ************* **************************** ** ****
  1008. 0.4 ************* ************************************
  1009. 0.2 ************* ************************************
  1010. 0.0 --------------------------------------------------
  1011.  
  1012. Multilevel CTCTGGAAGAGCAACCAGTGCTCTTAACCCCTGAGCCATCTCTCAACCCC
  1013. consensus T GA CCTC CG CTA T G CT TA CCAT C C A CGG
  1014. sequence G G C C T
  1015. T
  1016. --------------------------------------------------------------------------------
  1017.  
  1018. --------------------------------------------------------------------------------
  1019. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 sites sorted by position p-value
  1020. --------------------------------------------------------------------------------
  1021. Sequence name Strand Start P-value Site
  1022. ------------- ------ ----- --------- --------------------------------------------------
  1023. Htr6 + 8796 6.63e-26 GAACCAGGTC TTCTGCAAGAGCAACCAGTGCTCTTATCCACTGAGCCATCTCTCCAGCCC CTTATTTTAA
  1024. Arl13b - 23039 8.16e-26 AACTCAGGAC CTCTGGAAGAGCAGTCAGTGCTCTTAACCGCTGAACCATCTCACCAGCCC AGCTACTTAT
  1025. Kiss1r + 6288 1.04e-24 AACTAAGGCT CTGTGGCAGAGGATCCAGTTCTCTTAACCCCTGAGCCATCCCTCAGCCCC ACCTTATGGG
  1026. Sstr3 - 11088 4.25e-21 AGGAGGTTGG CTCAGGATCACCACCAAGTTCTGTTCTCTCCTCCCTCCTCTCCCATCCCC CACCCTCTTC
  1027. --------------------------------------------------------------------------------
  1028.  
  1029. --------------------------------------------------------------------------------
  1030. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 block diagrams
  1031. --------------------------------------------------------------------------------
  1032. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  1033. ------------- ---------------- -------------
  1034. Htr6 6.6e-26 8795_[+6]_6972
  1035. Arl13b 8.2e-26 23038_[-6]_30658
  1036. Kiss1r 1e-24 6287_[+6]_792
  1037. Sstr3 4.3e-21 11087_[-6]_1219
  1038. --------------------------------------------------------------------------------
  1039.  
  1040. --------------------------------------------------------------------------------
  1041. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 in BLOCKS format
  1042. --------------------------------------------------------------------------------
  1043. BL MOTIF CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC width=50 seqs=4
  1044. Htr6 ( 8796) TTCTGCAAGAGCAACCAGTGCTCTTATCCACTGAGCCATCTCTCCAGCCC 1
  1045. Arl13b ( 23039) CTCTGGAAGAGCAGTCAGTGCTCTTAACCGCTGAACCATCTCACCAGCCC 1
  1046. Kiss1r ( 6288) CTGTGGCAGAGGATCCAGTTCTCTTAACCCCTGAGCCATCCCTCAGCCCC 1
  1047. Sstr3 ( 11088) CTCAGGATCACCACCAAGTTCTGTTCTCTCCTCCCTCCTCTCCCATCCCC 1
  1048. //
  1049.  
  1050. --------------------------------------------------------------------------------
  1051.  
  1052. --------------------------------------------------------------------------------
  1053. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 position-specific scoring matrix
  1054. --------------------------------------------------------------------------------
  1055. log-odds matrix: alength= 4 w= 50 n= 109988 bayes= 14.7469 E= 1.9e-004
  1056. -865 172 -865 -12
  1057. -865 -865 -865 187
  1058. -865 172 14 -865
  1059. -12 -865 -865 146
  1060. -865 -865 213 -865
  1061. -865 14 172 -865
  1062. 146 14 -865 -865
  1063. 146 -865 -865 -12
  1064. -865 14 172 -865
  1065. 187 -865 -865 -865
  1066. -865 14 172 -865
  1067. -865 172 14 -865
  1068. 187 -865 -865 -865
  1069. -12 14 14 -12
  1070. -865 172 -865 -12
  1071. -12 172 -865 -865
  1072. 187 -865 -865 -865
  1073. -865 -865 213 -865
  1074. -865 -865 -865 187
  1075. -865 -865 113 87
  1076. -865 213 -865 -865
  1077. -865 -865 -865 187
  1078. -865 172 14 -865
  1079. -865 -865 -865 187
  1080. -865 -865 -865 187
  1081. 146 14 -865 -865
  1082. 87 -865 -865 87
  1083. -865 213 -865 -865
  1084. -865 172 -865 -12
  1085. -12 113 14 -865
  1086. -865 213 -865 -865
  1087. -865 -865 -865 187
  1088. -865 14 172 -865
  1089. 146 14 -865 -865
  1090. -12 14 113 -865
  1091. -865 172 -865 -12
  1092. -865 213 -865 -865
  1093. 146 14 -865 -865
  1094. -865 -865 -865 187
  1095. -865 213 -865 -865
  1096. -865 14 -865 146
  1097. -865 213 -865 -865
  1098. -12 14 -865 87
  1099. -865 213 -865 -865
  1100. 87 113 -865 -865
  1101. 87 -865 14 -12
  1102. -865 113 113 -865
  1103. -865 213 -865 -865
  1104. -865 213 -865 -865
  1105. -865 213 -865 -865
  1106. --------------------------------------------------------------------------------
  1107.  
  1108. --------------------------------------------------------------------------------
  1109. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 position-specific probability matrix
  1110. --------------------------------------------------------------------------------
  1111. letter-probability matrix: alength= 4 w= 50 nsites= 4 E= 1.9e-004
  1112. 0.000000 0.750000 0.000000 0.250000
  1113. 0.000000 0.000000 0.000000 1.000000
  1114. 0.000000 0.750000 0.250000 0.000000
  1115. 0.250000 0.000000 0.000000 0.750000
  1116. 0.000000 0.000000 1.000000 0.000000
  1117. 0.000000 0.250000 0.750000 0.000000
  1118. 0.750000 0.250000 0.000000 0.000000
  1119. 0.750000 0.000000 0.000000 0.250000
  1120. 0.000000 0.250000 0.750000 0.000000
  1121. 1.000000 0.000000 0.000000 0.000000
  1122. 0.000000 0.250000 0.750000 0.000000
  1123. 0.000000 0.750000 0.250000 0.000000
  1124. 1.000000 0.000000 0.000000 0.000000
  1125. 0.250000 0.250000 0.250000 0.250000
  1126. 0.000000 0.750000 0.000000 0.250000
  1127. 0.250000 0.750000 0.000000 0.000000
  1128. 1.000000 0.000000 0.000000 0.000000
  1129. 0.000000 0.000000 1.000000 0.000000
  1130. 0.000000 0.000000 0.000000 1.000000
  1131. 0.000000 0.000000 0.500000 0.500000
  1132. 0.000000 1.000000 0.000000 0.000000
  1133. 0.000000 0.000000 0.000000 1.000000
  1134. 0.000000 0.750000 0.250000 0.000000
  1135. 0.000000 0.000000 0.000000 1.000000
  1136. 0.000000 0.000000 0.000000 1.000000
  1137. 0.750000 0.250000 0.000000 0.000000
  1138. 0.500000 0.000000 0.000000 0.500000
  1139. 0.000000 1.000000 0.000000 0.000000
  1140. 0.000000 0.750000 0.000000 0.250000
  1141. 0.250000 0.500000 0.250000 0.000000
  1142. 0.000000 1.000000 0.000000 0.000000
  1143. 0.000000 0.000000 0.000000 1.000000
  1144. 0.000000 0.250000 0.750000 0.000000
  1145. 0.750000 0.250000 0.000000 0.000000
  1146. 0.250000 0.250000 0.500000 0.000000
  1147. 0.000000 0.750000 0.000000 0.250000
  1148. 0.000000 1.000000 0.000000 0.000000
  1149. 0.750000 0.250000 0.000000 0.000000
  1150. 0.000000 0.000000 0.000000 1.000000
  1151. 0.000000 1.000000 0.000000 0.000000
  1152. 0.000000 0.250000 0.000000 0.750000
  1153. 0.000000 1.000000 0.000000 0.000000
  1154. 0.250000 0.250000 0.000000 0.500000
  1155. 0.000000 1.000000 0.000000 0.000000
  1156. 0.500000 0.500000 0.000000 0.000000
  1157. 0.500000 0.000000 0.250000 0.250000
  1158. 0.000000 0.500000 0.500000 0.000000
  1159. 0.000000 1.000000 0.000000 0.000000
  1160. 0.000000 1.000000 0.000000 0.000000
  1161. 0.000000 1.000000 0.000000 0.000000
  1162. --------------------------------------------------------------------------------
  1163.  
  1164. --------------------------------------------------------------------------------
  1165. Motif CTCTGGAAGAGCANCCAGTKCTCTTAWCCVCTGAVCCATCTCHCMDSCCC MEME-6 regular expression
  1166. --------------------------------------------------------------------------------
  1167. [CT]T[CG][TA]G[GC][AC][AT][GC]A[GC][CG]A[ACGT][CT][CA]AGT[GT]CT[CG]TT[AC][AT]C[CT][CAG]CT[GC][AC][GAC][CT]C[AC]TC[TC]C[TAC]C[AC][AGT][CG]CCC
  1168. --------------------------------------------------------------------------------
  1169.  
  1170.  
  1171.  
  1172.  
  1173. Time 3802.65 secs.
  1174.  
  1175. ********************************************************************************
  1176.  
  1177.  
  1178. ********************************************************************************
  1179. MOTIF TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 width = 29 sites = 8 llr = 201 E-value = 2.5e-004
  1180. ********************************************************************************
  1181. --------------------------------------------------------------------------------
  1182. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 Description
  1183. --------------------------------------------------------------------------------
  1184. Simplified A 1:::3::113:::314::1::::1::::1
  1185. pos.-specific C :345163::::::::::::114:1:::::
  1186. probability G :411:31818:a14:6:6:9:6:84a:a:
  1187. matrix T 945461618:a:949:a49:9:a:6:a:9
  1188.  
  1189. bits 2.1 * * *
  1190. 1.9 ** * * ***
  1191. 1.7 ** * * ***
  1192. 1.5 ** * * * ***
  1193. Relative 1.3 * **** * * ***** ****
  1194. Entropy 1.1 * * **** ***************
  1195. (36.3 bits) 0.9 * * ****** ***************
  1196. 0.6 * *********** ***************
  1197. 0.4 *****************************
  1198. 0.2 *****************************
  1199. 0.0 -----------------------------
  1200.  
  1201. Multilevel TGTCTCTGTGTGTGTGTGTGTGTGTGTGT
  1202. consensus TCTAGC A T A T C G
  1203. sequence C A
  1204.  
  1205. --------------------------------------------------------------------------------
  1206.  
  1207. --------------------------------------------------------------------------------
  1208. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 sites sorted by position p-value
  1209. --------------------------------------------------------------------------------
  1210. Sequence name Strand Start P-value Site
  1211. ------------- ------ ----- --------- -----------------------------
  1212. Arl13b + 13906 3.39e-18 TGTGTGTGTG TGTCTCTGTGTGTGTGTGTGTGTGTGTGT GTGTTTGTCT
  1213. Npy2r + 6026 6.27e-15 TGTGTGTGTG TGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTATGGTA
  1214. Sstr3 + 104 5.90e-14 TTTTTATGCT TTGTTTTGTGTGTGTGTGTGTGTGTGTGT TTTATTTGGT
  1215. Htr6 + 10028 3.60e-13 ATATTTATTT ATTCACTGTGTGTATATTTGTGTGTGTGT TCTAGCACAC
  1216. Drd1 - 3509 7.82e-12 GTTAGTCACT TCTTACCTTGTGTTTATTTGTGTCTGTGT TGAGTTAAGG
  1217. Kiss1r + 2976 1.26e-11 TTTTTAAATT TTCTTGTGTATGGATGTTTGCCTGGGTGT ATATCTGCAC
  1218. Mchr1 + 43 9.98e-11 AACATGCATC TGCCTCCGAATGTTAATGTGTCTAGGTGA TGTCAGTGGG
  1219. Mc4r + 586 1.09e-10 ACTTTTTGTT TCCCCCGAGGTGTTTGTGACTCTGGGTGT CATAAGCCTG
  1220. --------------------------------------------------------------------------------
  1221.  
  1222. --------------------------------------------------------------------------------
  1223. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 block diagrams
  1224. --------------------------------------------------------------------------------
  1225. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  1226. ------------- ---------------- -------------
  1227. Arl13b 3.4e-18 13905_[+7]_39812
  1228. Npy2r 6.3e-15 6025_[+7]_4553
  1229. Sstr3 5.9e-14 103_[+7]_12224
  1230. Htr6 3.6e-13 10027_[+7]_5761
  1231. Drd1 7.8e-12 3508_[-7]_939
  1232. Kiss1r 1.3e-11 2975_[+7]_4125
  1233. Mchr1 1e-10 42_[+7]_3395
  1234. Mc4r 1.1e-10 585_[+7]_2169
  1235. --------------------------------------------------------------------------------
  1236.  
  1237. --------------------------------------------------------------------------------
  1238. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 in BLOCKS format
  1239. --------------------------------------------------------------------------------
  1240. BL MOTIF TBYYTCTGTGTGTDTRTKTGTSTGKGTGT width=29 seqs=8
  1241. Arl13b ( 13906) TGTCTCTGTGTGTGTGTGTGTGTGTGTGT 1
  1242. Npy2r ( 6026) TGTGTGTGTGTGTGTGTGTGTGTGTGTGT 1
  1243. Sstr3 ( 104) TTGTTTTGTGTGTGTGTGTGTGTGTGTGT 1
  1244. Htr6 ( 10028) ATTCACTGTGTGTATATTTGTGTGTGTGT 1
  1245. Drd1 ( 3509) TCTTACCTTGTGTTTATTTGTGTCTGTGT 1
  1246. Kiss1r ( 2976) TTCTTGTGTATGGATGTTTGCCTGGGTGT 1
  1247. Mchr1 ( 43) TGCCTCCGAATGTTAATGTGTCTAGGTGA 1
  1248. Mc4r ( 586) TCCCCCGAGGTGTTTGTGACTCTGGGTGT 1
  1249. //
  1250.  
  1251. --------------------------------------------------------------------------------
  1252.  
  1253. --------------------------------------------------------------------------------
  1254. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 position-specific scoring matrix
  1255. --------------------------------------------------------------------------------
  1256. log-odds matrix: alength= 4 w= 29 n= 110156 bayes= 13.9011 E= 2.5e-004
  1257. -112 -965 -965 168
  1258. -965 14 72 46
  1259. -965 72 -86 88
  1260. -965 113 -86 46
  1261. -12 -86 -965 120
  1262. -965 146 14 -112
  1263. -965 14 -86 120
  1264. -112 -965 172 -112
  1265. -112 -965 -86 146
  1266. -12 -965 172 -965
  1267. -965 -965 -965 187
  1268. -965 -965 213 -965
  1269. -965 -965 -86 168
  1270. -12 -965 72 46
  1271. -112 -965 -965 168
  1272. 46 -965 146 -965
  1273. -965 -965 -965 187
  1274. -965 -965 146 46
  1275. -112 -965 -965 168
  1276. -965 -86 194 -965
  1277. -965 -86 -965 168
  1278. -965 72 146 -965
  1279. -965 -965 -965 187
  1280. -112 -86 172 -965
  1281. -965 -965 72 120
  1282. -965 -965 213 -965
  1283. -965 -965 -965 187
  1284. -965 -965 213 -965
  1285. -112 -965 -965 168
  1286. --------------------------------------------------------------------------------
  1287.  
  1288. --------------------------------------------------------------------------------
  1289. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 position-specific probability matrix
  1290. --------------------------------------------------------------------------------
  1291. letter-probability matrix: alength= 4 w= 29 nsites= 8 E= 2.5e-004
  1292. 0.125000 0.000000 0.000000 0.875000
  1293. 0.000000 0.250000 0.375000 0.375000
  1294. 0.000000 0.375000 0.125000 0.500000
  1295. 0.000000 0.500000 0.125000 0.375000
  1296. 0.250000 0.125000 0.000000 0.625000
  1297. 0.000000 0.625000 0.250000 0.125000
  1298. 0.000000 0.250000 0.125000 0.625000
  1299. 0.125000 0.000000 0.750000 0.125000
  1300. 0.125000 0.000000 0.125000 0.750000
  1301. 0.250000 0.000000 0.750000 0.000000
  1302. 0.000000 0.000000 0.000000 1.000000
  1303. 0.000000 0.000000 1.000000 0.000000
  1304. 0.000000 0.000000 0.125000 0.875000
  1305. 0.250000 0.000000 0.375000 0.375000
  1306. 0.125000 0.000000 0.000000 0.875000
  1307. 0.375000 0.000000 0.625000 0.000000
  1308. 0.000000 0.000000 0.000000 1.000000
  1309. 0.000000 0.000000 0.625000 0.375000
  1310. 0.125000 0.000000 0.000000 0.875000
  1311. 0.000000 0.125000 0.875000 0.000000
  1312. 0.000000 0.125000 0.000000 0.875000
  1313. 0.000000 0.375000 0.625000 0.000000
  1314. 0.000000 0.000000 0.000000 1.000000
  1315. 0.125000 0.125000 0.750000 0.000000
  1316. 0.000000 0.000000 0.375000 0.625000
  1317. 0.000000 0.000000 1.000000 0.000000
  1318. 0.000000 0.000000 0.000000 1.000000
  1319. 0.000000 0.000000 1.000000 0.000000
  1320. 0.125000 0.000000 0.000000 0.875000
  1321. --------------------------------------------------------------------------------
  1322.  
  1323. --------------------------------------------------------------------------------
  1324. Motif TBYYTCTGTGTGTDTRTKTGTSTGKGTGT MEME-7 regular expression
  1325. --------------------------------------------------------------------------------
  1326. T[GTC][TC][CT][TA][CG][TC]GT[GA]TGT[GTA]T[GA]T[GT]TGT[GC]TG[TG]GTGT
  1327. --------------------------------------------------------------------------------
  1328.  
  1329.  
  1330.  
  1331.  
  1332. Time 4424.16 secs.
  1333.  
  1334. ********************************************************************************
  1335.  
  1336.  
  1337. ********************************************************************************
  1338. MOTIF AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 width = 29 sites = 7 llr = 182 E-value = 9.1e-005
  1339. ********************************************************************************
  1340. --------------------------------------------------------------------------------
  1341. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 Description
  1342. --------------------------------------------------------------------------------
  1343. Simplified A 9:7:63a:719:7671a:914:614:3a:
  1344. pos.-specific C :::::1::::::1::1::1::3::311::
  1345. probability G 1a3a46:a391a1436:a:96439364:a
  1346. matrix T :::::::::::::::1:::::31::31::
  1347.  
  1348. bits 2.1 * * * * * *
  1349. 1.9 * * ** * ** **
  1350. 1.7 * * ** * ** **
  1351. 1.5 * * ** * * ** * * **
  1352. Relative 1.3 ** * ** *** **** * **
  1353. Entropy 1.1 ***** ****** ** ***** * **
  1354. (37.5 bits) 0.9 ***** ********* ***** * **
  1355. 0.6 *************** ***** ** * **
  1356. 0.4 ************************** **
  1357. 0.2 *****************************
  1358. 0.0 -----------------------------
  1359.  
  1360. Multilevel AGAGAGAGAGAGAAAGAGAGGGAGAGGAG
  1361. consensus G GA G GG ACG CTA
  1362. sequence T G
  1363.  
  1364. --------------------------------------------------------------------------------
  1365.  
  1366. --------------------------------------------------------------------------------
  1367. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 sites sorted by position p-value
  1368. --------------------------------------------------------------------------------
  1369. Sequence name Strand Start P-value Site
  1370. ------------- ------ ----- --------- -----------------------------
  1371. Htr6 - 10579 5.62e-17 AGAGAGAGAG AGAGAGAGAGAGAGAGAGAGAGAGAGGAG AGAGGAGAGA
  1372. Arl13b + 32057 3.54e-16 AGAGAGAGAG AGAGAGAGAGAGAGAGAGAGAGAGAGAAG AAAATATAAT
  1373. Sstr3 + 11042 6.87e-14 TGAGGCAAGA AGAGGGAGAAAGAAGGAGAGGGAGATGAG GTAGTAGGAA
  1374. Npy2r + 5093 9.81e-14 AAGAGACAGG AGGGAGAGAGAGAAAGAGAGGCAGCCTAG TTGGGGGATC
  1375. Kiss1r + 1685 4.72e-12 AAGGTTGCCT GGAGGAAGAGAGCGACAGAGGTGGGGAAG CATGGCCACC
  1376. Mchr1 + 530 1.30e-11 CTAGGACAGA AGGGGCAGGGAGGAATAGAGATGGGGCAG AGGCACATTT
  1377. Mc4r + 2015 1.49e-10 AGTAAAGGAA AGAGAAAGGGGGAAGAAGCAGCTACTGAG GAGAAAGTGA
  1378. --------------------------------------------------------------------------------
  1379.  
  1380. --------------------------------------------------------------------------------
  1381. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 block diagrams
  1382. --------------------------------------------------------------------------------
  1383. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  1384. ------------- ---------------- -------------
  1385. Htr6 5.6e-17 10578_[-8]_5210
  1386. Arl13b 3.5e-16 32056_[+8]_21661
  1387. Sstr3 6.9e-14 11041_[+8]_1286
  1388. Npy2r 9.8e-14 5092_[+8]_5486
  1389. Kiss1r 4.7e-12 1684_[+8]_5416
  1390. Mchr1 1.3e-11 529_[+8]_2908
  1391. Mc4r 1.5e-10 2014_[+8]_740
  1392. --------------------------------------------------------------------------------
  1393.  
  1394. --------------------------------------------------------------------------------
  1395. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 in BLOCKS format
  1396. --------------------------------------------------------------------------------
  1397. BL MOTIF AGAGRRAGAGAGARAGAGAGRBRGVKRAG width=29 seqs=7
  1398. Htr6 ( 10579) AGAGAGAGAGAGAGAGAGAGAGAGAGGAG 1
  1399. Arl13b ( 32057) AGAGAGAGAGAGAGAGAGAGAGAGAGAAG 1
  1400. Sstr3 ( 11042) AGAGGGAGAAAGAAGGAGAGGGAGATGAG 1
  1401. Npy2r ( 5093) AGGGAGAGAGAGAAAGAGAGGCAGCCTAG 1
  1402. Kiss1r ( 1685) GGAGGAAGAGAGCGACAGAGGTGGGGAAG 1
  1403. Mchr1 ( 530) AGGGGCAGGGAGGAATAGAGATGGGGCAG 1
  1404. Mc4r ( 2015) AGAGAAAGGGGGAAGAAGCAGCTACTGAG 1
  1405. //
  1406.  
  1407. --------------------------------------------------------------------------------
  1408.  
  1409. --------------------------------------------------------------------------------
  1410. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 position-specific scoring matrix
  1411. --------------------------------------------------------------------------------
  1412. log-odds matrix: alength= 4 w= 29 n= 110156 bayes= 14.5475 E= 9.1e-005
  1413. 165 -945 -67 -945
  1414. -945 -945 213 -945
  1415. 139 -945 33 -945
  1416. -945 -945 213 -945
  1417. 107 -945 91 -945
  1418. 7 -67 133 -945
  1419. 187 -945 -945 -945
  1420. -945 -945 213 -945
  1421. 139 -945 33 -945
  1422. -93 -945 191 -945
  1423. 165 -945 -67 -945
  1424. -945 -945 213 -945
  1425. 139 -67 -67 -945
  1426. 107 -945 91 -945
  1427. 139 -945 33 -945
  1428. -93 -67 133 -93
  1429. 187 -945 -945 -945
  1430. -945 -945 213 -945
  1431. 165 -67 -945 -945
  1432. -93 -945 191 -945
  1433. 65 -945 133 -945
  1434. -945 33 91 7
  1435. 107 -945 33 -93
  1436. -93 -945 191 -945
  1437. 65 33 33 -945
  1438. -945 -67 133 7
  1439. 7 -67 91 -93
  1440. 187 -945 -945 -945
  1441. -945 -945 213 -945
  1442. --------------------------------------------------------------------------------
  1443.  
  1444. --------------------------------------------------------------------------------
  1445. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 position-specific probability matrix
  1446. --------------------------------------------------------------------------------
  1447. letter-probability matrix: alength= 4 w= 29 nsites= 7 E= 9.1e-005
  1448. 0.857143 0.000000 0.142857 0.000000
  1449. 0.000000 0.000000 1.000000 0.000000
  1450. 0.714286 0.000000 0.285714 0.000000
  1451. 0.000000 0.000000 1.000000 0.000000
  1452. 0.571429 0.000000 0.428571 0.000000
  1453. 0.285714 0.142857 0.571429 0.000000
  1454. 1.000000 0.000000 0.000000 0.000000
  1455. 0.000000 0.000000 1.000000 0.000000
  1456. 0.714286 0.000000 0.285714 0.000000
  1457. 0.142857 0.000000 0.857143 0.000000
  1458. 0.857143 0.000000 0.142857 0.000000
  1459. 0.000000 0.000000 1.000000 0.000000
  1460. 0.714286 0.142857 0.142857 0.000000
  1461. 0.571429 0.000000 0.428571 0.000000
  1462. 0.714286 0.000000 0.285714 0.000000
  1463. 0.142857 0.142857 0.571429 0.142857
  1464. 1.000000 0.000000 0.000000 0.000000
  1465. 0.000000 0.000000 1.000000 0.000000
  1466. 0.857143 0.142857 0.000000 0.000000
  1467. 0.142857 0.000000 0.857143 0.000000
  1468. 0.428571 0.000000 0.571429 0.000000
  1469. 0.000000 0.285714 0.428571 0.285714
  1470. 0.571429 0.000000 0.285714 0.142857
  1471. 0.142857 0.000000 0.857143 0.000000
  1472. 0.428571 0.285714 0.285714 0.000000
  1473. 0.000000 0.142857 0.571429 0.285714
  1474. 0.285714 0.142857 0.428571 0.142857
  1475. 1.000000 0.000000 0.000000 0.000000
  1476. 0.000000 0.000000 1.000000 0.000000
  1477. --------------------------------------------------------------------------------
  1478.  
  1479. --------------------------------------------------------------------------------
  1480. Motif AGAGRRAGAGAGARAGAGAGRBRGVKRAG MEME-8 regular expression
  1481. --------------------------------------------------------------------------------
  1482. AG[AG]G[AG][GA]AG[AG]GAGA[AG][AG]GAGAG[GA][GCT][AG]G[ACG][GT][GA]AG
  1483. --------------------------------------------------------------------------------
  1484.  
  1485.  
  1486.  
  1487.  
  1488. Time 5044.73 secs.
  1489.  
  1490. ********************************************************************************
  1491.  
  1492.  
  1493. ********************************************************************************
  1494. MOTIF TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 width = 41 sites = 7 llr = 222 E-value = 6.2e-004
  1495. ********************************************************************************
  1496. --------------------------------------------------------------------------------
  1497. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 Description
  1498. --------------------------------------------------------------------------------
  1499. Simplified A ::1:::::::::31:11:1:4661::::3:6::6671::::
  1500. pos.-specific C :9716a319a1a:1a4176911:41a1:134:63:1:34:3
  1501. probability G :1:43:161::::6::::::3:414:3a67:3::3197:a:
  1502. matrix T a:141:63::9:71:4733113:34:6::::7411:::6:7
  1503.  
  1504. bits 2.1 * * * * * * *
  1505. 1.9 * * * * * * * *
  1506. 1.7 * * * * * * * *
  1507. 1.5 ** * ** * * * * * * *
  1508. Relative 1.3 ** * **** * * * * * * ** *
  1509. Entropy 1.1 ** * ***** * * * * * * **** *****
  1510. (45.7 bits) 0.9 *** * ***** * ** * * * * **** ******
  1511. 0.6 ************* ****** ** *****************
  1512. 0.4 ******************** ** *****************
  1513. 0.2 *****************************************
  1514. 0.0 -----------------------------------------
  1515.  
  1516. Multilevel TCCGCCTGCCTCTGCCTCCCAAACGCTGGGATCAAAGGTGT
  1517. consensus TG CT A T TT GTGTT G ACCGTCG CC C
  1518. sequence
  1519.  
  1520. --------------------------------------------------------------------------------
  1521.  
  1522. --------------------------------------------------------------------------------
  1523. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 sites sorted by position p-value
  1524. --------------------------------------------------------------------------------
  1525. Sequence name Strand Start P-value Site
  1526. ------------- ------ ----- --------- -----------------------------------------
  1527. Arl13b + 19377 1.30e-22 AACTCAGAAG TCCGCCTGCCTCTGCTTCCCAAATGCTGGGATTAAAGGCGT GCGCCACCAC
  1528. Kiss1r - 5632 1.15e-20 CTAACAGAGA TCCTCCTGCCTCTGCCTCTCAAAAGCTGGGATTAAAGGCGT GGCCATCTCA
  1529. Htr6 + 10228 6.16e-18 CTCACAGAAA TCTGCCCGCCTCTGCTTCCCAAGTGCTGGGATTAAGGGTGC ATTTCACGAT
  1530. Sstr3 - 302 9.92e-15 GCACAGTTGA TCCTTCTGCCTCAACCTTCCGAGGTCTGAGCTCCTAAGTGT TGGCCACCCC
  1531. Npy2r + 877 7.27e-14 TCTCCGATCC TCCTCCCTCCCCACCCACTCCTACCCGGGGCTCTGAGCTGT GCAGTGCGGG
  1532. Drd1 - 7 4.23e-13 CCCTCTCCTG TGCCGCTCGCTCTGCTCTCCGCGCTCCGCCCGCCAAGGCGC TTCTGC
  1533. Mc4r + 985 1.03e-12 TTGCACTGTG TCAGGCGTCCTCTTCATCATTTACTCGGACAGCAGCGCTGT CATCATCTGC
  1534. --------------------------------------------------------------------------------
  1535.  
  1536. --------------------------------------------------------------------------------
  1537. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 block diagrams
  1538. --------------------------------------------------------------------------------
  1539. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  1540. ------------- ---------------- -------------
  1541. Arl13b 1.3e-22 19376_[+9]_34329
  1542. Kiss1r 1.1e-20 5631_[-9]_1457
  1543. Htr6 6.2e-18 10227_[+9]_5549
  1544. Sstr3 9.9e-15 301_[-9]_12014
  1545. Npy2r 7.3e-14 876_[+9]_9690
  1546. Drd1 4.2e-13 6_[-9]_4429
  1547. Mc4r 1e-12 984_[+9]_1758
  1548. --------------------------------------------------------------------------------
  1549.  
  1550. --------------------------------------------------------------------------------
  1551. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 in BLOCKS format
  1552. --------------------------------------------------------------------------------
  1553. BL MOTIF TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT width=41 seqs=7
  1554. Arl13b ( 19377) TCCGCCTGCCTCTGCTTCCCAAATGCTGGGATTAAAGGCGT 1
  1555. Kiss1r ( 5632) TCCTCCTGCCTCTGCCTCTCAAAAGCTGGGATTAAAGGCGT 1
  1556. Htr6 ( 10228) TCTGCCCGCCTCTGCTTCCCAAGTGCTGGGATTAAGGGTGC 1
  1557. Sstr3 ( 302) TCCTTCTGCCTCAACCTTCCGAGGTCTGAGCTCCTAAGTGT 1
  1558. Npy2r ( 877) TCCTCCCTCCCCACCCACTCCTACCCGGGGCTCTGAGCTGT 1
  1559. Drd1 ( 7) TGCCGCTCGCTCTGCTCTCCGCGCTCCGCCCGCCAAGGCGC 1
  1560. Mc4r ( 985) TCAGGCGTCCTCTTCATCATTTACTCGGACAGCAGCGCTGT 1
  1561. //
  1562.  
  1563. --------------------------------------------------------------------------------
  1564.  
  1565. --------------------------------------------------------------------------------
  1566. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 position-specific scoring matrix
  1567. --------------------------------------------------------------------------------
  1568. log-odds matrix: alength= 4 w= 41 n= 110060 bayes= 14.5462 E= 6.2e-004
  1569. -945 -945 -945 187
  1570. -945 191 -67 -945
  1571. -93 165 -945 -93
  1572. -945 -67 91 65
  1573. -945 133 33 -93
  1574. -945 213 -945 -945
  1575. -945 33 -67 107
  1576. -945 -67 133 7
  1577. -945 191 -67 -945
  1578. -945 213 -945 -945
  1579. -945 -67 -945 165
  1580. -945 213 -945 -945
  1581. 7 -945 -945 139
  1582. -93 -67 133 -93
  1583. -945 213 -945 -945
  1584. -93 91 -945 65
  1585. -93 -67 -945 139
  1586. -945 165 -945 7
  1587. -93 133 -945 7
  1588. -945 191 -945 -93
  1589. 65 -67 33 -93
  1590. 107 -67 -945 7
  1591. 107 -945 91 -945
  1592. -93 91 -67 7
  1593. -945 -67 91 65
  1594. -945 213 -945 -945
  1595. -945 -67 33 107
  1596. -945 -945 213 -945
  1597. 7 -67 133 -945
  1598. -945 33 165 -945
  1599. 107 91 -945 -945
  1600. -945 -945 33 139
  1601. -945 133 -945 65
  1602. 107 33 -945 -93
  1603. 107 -945 33 -93
  1604. 139 -67 -67 -945
  1605. -93 -945 191 -945
  1606. -945 33 165 -945
  1607. -945 91 -945 107
  1608. -945 -945 213 -945
  1609. -945 33 -945 139
  1610. --------------------------------------------------------------------------------
  1611.  
  1612. --------------------------------------------------------------------------------
  1613. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 position-specific probability matrix
  1614. --------------------------------------------------------------------------------
  1615. letter-probability matrix: alength= 4 w= 41 nsites= 7 E= 6.2e-004
  1616. 0.000000 0.000000 0.000000 1.000000
  1617. 0.000000 0.857143 0.142857 0.000000
  1618. 0.142857 0.714286 0.000000 0.142857
  1619. 0.000000 0.142857 0.428571 0.428571
  1620. 0.000000 0.571429 0.285714 0.142857
  1621. 0.000000 1.000000 0.000000 0.000000
  1622. 0.000000 0.285714 0.142857 0.571429
  1623. 0.000000 0.142857 0.571429 0.285714
  1624. 0.000000 0.857143 0.142857 0.000000
  1625. 0.000000 1.000000 0.000000 0.000000
  1626. 0.000000 0.142857 0.000000 0.857143
  1627. 0.000000 1.000000 0.000000 0.000000
  1628. 0.285714 0.000000 0.000000 0.714286
  1629. 0.142857 0.142857 0.571429 0.142857
  1630. 0.000000 1.000000 0.000000 0.000000
  1631. 0.142857 0.428571 0.000000 0.428571
  1632. 0.142857 0.142857 0.000000 0.714286
  1633. 0.000000 0.714286 0.000000 0.285714
  1634. 0.142857 0.571429 0.000000 0.285714
  1635. 0.000000 0.857143 0.000000 0.142857
  1636. 0.428571 0.142857 0.285714 0.142857
  1637. 0.571429 0.142857 0.000000 0.285714
  1638. 0.571429 0.000000 0.428571 0.000000
  1639. 0.142857 0.428571 0.142857 0.285714
  1640. 0.000000 0.142857 0.428571 0.428571
  1641. 0.000000 1.000000 0.000000 0.000000
  1642. 0.000000 0.142857 0.285714 0.571429
  1643. 0.000000 0.000000 1.000000 0.000000
  1644. 0.285714 0.142857 0.571429 0.000000
  1645. 0.000000 0.285714 0.714286 0.000000
  1646. 0.571429 0.428571 0.000000 0.000000
  1647. 0.000000 0.000000 0.285714 0.714286
  1648. 0.000000 0.571429 0.000000 0.428571
  1649. 0.571429 0.285714 0.000000 0.142857
  1650. 0.571429 0.000000 0.285714 0.142857
  1651. 0.714286 0.142857 0.142857 0.000000
  1652. 0.142857 0.000000 0.857143 0.000000
  1653. 0.000000 0.285714 0.714286 0.000000
  1654. 0.000000 0.428571 0.000000 0.571429
  1655. 0.000000 0.000000 1.000000 0.000000
  1656. 0.000000 0.285714 0.000000 0.714286
  1657. --------------------------------------------------------------------------------
  1658.  
  1659. --------------------------------------------------------------------------------
  1660. Motif TCCKSCYKCCTCTGCYTCYCRWRYKCKGRGMTYMRAGGYGT MEME-9 regular expression
  1661. --------------------------------------------------------------------------------
  1662. TCC[GT][CG]C[TC][GT]CCTC[TA]GC[CT]T[CT][CT]C[AG][AT][AG][CT][GT]C[TG]G[GA][GC][AC][TG][CT][AC][AG]AG[GC][TC]G[TC]
  1663. --------------------------------------------------------------------------------
  1664.  
  1665.  
  1666.  
  1667.  
  1668. Time 5662.87 secs.
  1669.  
  1670. ********************************************************************************
  1671.  
  1672.  
  1673. ********************************************************************************
  1674. MOTIF ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 width = 50 sites = 6 llr = 234 E-value = 6.3e-004
  1675. ********************************************************************************
  1676. --------------------------------------------------------------------------------
  1677. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 Description
  1678. --------------------------------------------------------------------------------
  1679. Simplified A 82::::7:2:::a::5::2:::a:2:::8::2:2::8::::::7::2:3:
  1680. pos.-specific C :378:3273258::2:533::::a8:82:35:2255:352:532788572
  1681. probability G :3:::7:227::::55525:8a:::a2:22:255222:27:3::22:5::
  1682. matrix T 2232a:223252:a3::5:a2::::::8:5573233:732a2722::::8
  1683.  
  1684. bits 2.1 * * *
  1685. 1.9 * ** * *** * *
  1686. 1.7 * ** * *** * *
  1687. 1.5 ** *** ******** * **
  1688. Relative 1.3 * *** *** ********** * * ** *
  1689. Entropy 1.1 * **** **** ** ********** * ** * * *****
  1690. (56.2 bits) 0.9 * **** * ***** ** ********** * ** ** * ******
  1691. 0.6 * ****** ************************ ****************
  1692. 0.4 * ****** ************************ ****************
  1693. 0.2 ******** *****************************************
  1694. 0.0 --------------------------------------------------
  1695.  
  1696. Multilevel ACCCTGACCGCCATGACTGTGGACCGCTATCTGGCCATCGTCTACCCCCT
  1697. consensus GT C T T TGGCC CT T TT CT GC GA
  1698. sequence
  1699.  
  1700. --------------------------------------------------------------------------------
  1701.  
  1702. --------------------------------------------------------------------------------
  1703. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 sites sorted by position p-value
  1704. --------------------------------------------------------------------------------
  1705. Sequence name Strand Start P-value Site
  1706. ------------- ------ ----- --------- --------------------------------------------------
  1707. Sstr3 + 9224 2.83e-20 CAGCATCTTC TGCCTCACCGTCATGAGTGTGGACCGCTATCTGGCTGTGGTGCACCCCAC ACGCTCAGCC
  1708. Mchr1 + 1949 1.35e-19 CAGCACCTAC ATCCTGACTGCTATGGCCATTGACCGCTACTTGGCCACCGTCCATCCCAT CTCCTCCACC
  1709. Kiss1r + 3760 3.19e-19 CACATGTGCC ACTCTGACGGCCATGAGTGTGGACCGCTGGTATGTGACTGTGTTCCCGCT GCGTGCACTT
  1710. Npy2r + 7941 2.30e-18 GTCCACAATA ACTTTGACAGTCATTGCTCTGGACCGCCATCGTTGCATTGTCTACCACCT GGAGAGCAAG
  1711. Htr6 + 1106 7.66e-18 CTCCATTCTC AACCTCTGCCTCATCAGCCTGGACCGCTACCTGCTCATCCTCTCGCCGCT GCGCTACAAG
  1712. Mc4r + 862 9.91e-17 ATCCATTTGC AGCCTGCTTTCCATTGCGGTGGACAGGTATTTCACTATCTTTTACGCGCT CCAGTACCAT
  1713. --------------------------------------------------------------------------------
  1714.  
  1715. --------------------------------------------------------------------------------
  1716. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 block diagrams
  1717. --------------------------------------------------------------------------------
  1718. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  1719. ------------- ---------------- -------------
  1720. Sstr3 2.8e-20 9223_[+10]_3083
  1721. Mchr1 1.4e-19 1948_[+10]_1468
  1722. Kiss1r 3.2e-19 3759_[+10]_3320
  1723. Npy2r 2.3e-18 7940_[+10]_2617
  1724. Htr6 7.7e-18 1105_[+10]_14662
  1725. Mc4r 9.9e-17 861_[+10]_1872
  1726. --------------------------------------------------------------------------------
  1727.  
  1728. --------------------------------------------------------------------------------
  1729. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 in BLOCKS format
  1730. --------------------------------------------------------------------------------
  1731. BL MOTIF ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT width=50 seqs=6
  1732. Sstr3 ( 9224) TGCCTCACCGTCATGAGTGTGGACCGCTATCTGGCTGTGGTGCACCCCAC 1
  1733. Mchr1 ( 1949) ATCCTGACTGCTATGGCCATTGACCGCTACTTGGCCACCGTCCATCCCAT 1
  1734. Kiss1r ( 3760) ACTCTGACGGCCATGAGTGTGGACCGCTGGTATGTGACTGTGTTCCCGCT 1
  1735. Npy2r ( 7941) ACTTTGACAGTCATTGCTCTGGACCGCCATCGTTGCATTGTCTACCACCT 1
  1736. Htr6 ( 1106) AACCTCTGCCTCATCAGCCTGGACCGCTACCTGCTCATCCTCTCGCCGCT 1
  1737. Mc4r ( 862) AGCCTGCTTTCCATTGCGGTGGACAGGTATTTCACTATCTTTTACGCGCT 1
  1738. //
  1739.  
  1740. --------------------------------------------------------------------------------
  1741.  
  1742. --------------------------------------------------------------------------------
  1743. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 position-specific scoring matrix
  1744. --------------------------------------------------------------------------------
  1745. log-odds matrix: alength= 4 w= 50 n= 109988 bayes= 13.9814 E= 6.3e-004
  1746. 161 -923 -923 -71
  1747. -71 55 55 -71
  1748. -923 155 -923 29
  1749. -923 187 -923 -71
  1750. -923 -923 -923 187
  1751. -923 55 155 -923
  1752. 129 -45 -923 -71
  1753. -923 155 -45 -71
  1754. -71 55 -45 29
  1755. -923 -45 155 -71
  1756. -923 113 -923 88
  1757. -923 187 -923 -71
  1758. 187 -923 -923 -923
  1759. -923 -923 -923 187
  1760. -923 -45 113 29
  1761. 88 -923 113 -923
  1762. -923 113 113 -923
  1763. -923 55 -45 88
  1764. -71 55 113 -923
  1765. -923 -923 -923 187
  1766. -923 -923 187 -71
  1767. -923 -923 213 -923
  1768. 187 -923 -923 -923
  1769. -923 213 -923 -923
  1770. -71 187 -923 -923
  1771. -923 -923 213 -923
  1772. -923 187 -45 -923
  1773. -923 -45 -923 161
  1774. 161 -923 -45 -923
  1775. -923 55 -45 88
  1776. -923 113 -923 88
  1777. -71 -923 -45 129
  1778. -923 -45 113 29
  1779. -71 -45 113 -71
  1780. -923 113 -45 29
  1781. -923 113 -45 29
  1782. 161 -923 -45 -923
  1783. -923 55 -923 129
  1784. -923 113 -45 29
  1785. -923 -45 155 -71
  1786. -923 -923 -923 187
  1787. -923 113 55 -71
  1788. -923 55 -923 129
  1789. 129 -45 -923 -71
  1790. -923 155 -45 -71
  1791. -923 187 -45 -923
  1792. -71 187 -923 -923
  1793. -923 113 113 -923
  1794. 29 155 -923 -923
  1795. -923 -45 -923 161
  1796. --------------------------------------------------------------------------------
  1797.  
  1798. --------------------------------------------------------------------------------
  1799. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 position-specific probability matrix
  1800. --------------------------------------------------------------------------------
  1801. letter-probability matrix: alength= 4 w= 50 nsites= 6 E= 6.3e-004
  1802. 0.833333 0.000000 0.000000 0.166667
  1803. 0.166667 0.333333 0.333333 0.166667
  1804. 0.000000 0.666667 0.000000 0.333333
  1805. 0.000000 0.833333 0.000000 0.166667
  1806. 0.000000 0.000000 0.000000 1.000000
  1807. 0.000000 0.333333 0.666667 0.000000
  1808. 0.666667 0.166667 0.000000 0.166667
  1809. 0.000000 0.666667 0.166667 0.166667
  1810. 0.166667 0.333333 0.166667 0.333333
  1811. 0.000000 0.166667 0.666667 0.166667
  1812. 0.000000 0.500000 0.000000 0.500000
  1813. 0.000000 0.833333 0.000000 0.166667
  1814. 1.000000 0.000000 0.000000 0.000000
  1815. 0.000000 0.000000 0.000000 1.000000
  1816. 0.000000 0.166667 0.500000 0.333333
  1817. 0.500000 0.000000 0.500000 0.000000
  1818. 0.000000 0.500000 0.500000 0.000000
  1819. 0.000000 0.333333 0.166667 0.500000
  1820. 0.166667 0.333333 0.500000 0.000000
  1821. 0.000000 0.000000 0.000000 1.000000
  1822. 0.000000 0.000000 0.833333 0.166667
  1823. 0.000000 0.000000 1.000000 0.000000
  1824. 1.000000 0.000000 0.000000 0.000000
  1825. 0.000000 1.000000 0.000000 0.000000
  1826. 0.166667 0.833333 0.000000 0.000000
  1827. 0.000000 0.000000 1.000000 0.000000
  1828. 0.000000 0.833333 0.166667 0.000000
  1829. 0.000000 0.166667 0.000000 0.833333
  1830. 0.833333 0.000000 0.166667 0.000000
  1831. 0.000000 0.333333 0.166667 0.500000
  1832. 0.000000 0.500000 0.000000 0.500000
  1833. 0.166667 0.000000 0.166667 0.666667
  1834. 0.000000 0.166667 0.500000 0.333333
  1835. 0.166667 0.166667 0.500000 0.166667
  1836. 0.000000 0.500000 0.166667 0.333333
  1837. 0.000000 0.500000 0.166667 0.333333
  1838. 0.833333 0.000000 0.166667 0.000000
  1839. 0.000000 0.333333 0.000000 0.666667
  1840. 0.000000 0.500000 0.166667 0.333333
  1841. 0.000000 0.166667 0.666667 0.166667
  1842. 0.000000 0.000000 0.000000 1.000000
  1843. 0.000000 0.500000 0.333333 0.166667
  1844. 0.000000 0.333333 0.000000 0.666667
  1845. 0.666667 0.166667 0.000000 0.166667
  1846. 0.000000 0.666667 0.166667 0.166667
  1847. 0.000000 0.833333 0.166667 0.000000
  1848. 0.166667 0.833333 0.000000 0.000000
  1849. 0.000000 0.500000 0.500000 0.000000
  1850. 0.333333 0.666667 0.000000 0.000000
  1851. 0.000000 0.166667 0.000000 0.833333
  1852. --------------------------------------------------------------------------------
  1853.  
  1854. --------------------------------------------------------------------------------
  1855. Motif ANYCTSACNGYCATKRSYSTGGACCGCTAYYTKGYYAYYGTSYACCCSMT MEME-10 regular expression
  1856. --------------------------------------------------------------------------------
  1857. A[CG][CT]CT[GC]AC[CT]G[CT]CAT[GT][AG][CG][TC][GC]TGGACCGCTA[TC][CT]T[GT]G[CT][CT]A[TC][CT]GT[CG][TC]ACCC[CG][CA]T
  1858. --------------------------------------------------------------------------------
  1859.  
  1860.  
  1861.  
  1862.  
  1863. Time 6278.74 secs.
  1864.  
  1865. ********************************************************************************
  1866.  
  1867.  
  1868. ********************************************************************************
  1869. MOTIF RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 width = 37 sites = 2 llr = 81 E-value = 1.5e-004
  1870. ********************************************************************************
  1871. --------------------------------------------------------------------------------
  1872. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 Description
  1873. --------------------------------------------------------------------------------
  1874. Simplified A 5a:5:555:a:a5::a::5::a::a:a:::55::::a
  1875. pos.-specific C ::5:a5:5a:5:::5::5:aa:55:a::aa::::a5:
  1876. probability G 5:55::::::5:555:a:::::55:::a::55aa:::
  1877. matrix T ::::::5::::::5:::55::::::::::::::::5:
  1878.  
  1879. bits 2.1 * * * ** * *** ***
  1880. 1.9 * * ** * ** *** ****** *** *
  1881. 1.7 * * ** * ** *** ****** *** *
  1882. 1.5 * * ** * ** *** ****** *** *
  1883. Relative 1.3 * * ** * ** *** ****** *** *
  1884. Entropy 1.1 ****** *********** ******************
  1885. (58.1 bits) 0.9 *************************************
  1886. 0.6 *************************************
  1887. 0.4 *************************************
  1888. 0.2 *************************************
  1889. 0.0 -------------------------------------
  1890.  
  1891. Multilevel AACACAAACACAAGCAGCACCACCACAGCCAAGGCCA
  1892. consensus G GG CTC G GTG TT GG GG T
  1893. sequence
  1894.  
  1895. --------------------------------------------------------------------------------
  1896.  
  1897. --------------------------------------------------------------------------------
  1898. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 sites sorted by position p-value
  1899. --------------------------------------------------------------------------------
  1900. Sequence name Strand Start P-value Site
  1901. ------------- ------ ----- --------- -------------------------------------
  1902. Sstr3 - 9333 9.25e-19 CACTCCTGAG AACACAACCACAGGCAGCACCACCACAGCCGAGGCCA CCCAGACAGC
  1903. Kiss1r + 5686 2.51e-18 CTGTTAGTTT GAGGCCTACAGAATGAGTTCCAGGACAGCCAGGGCTA CAGAGAGAGA
  1904. --------------------------------------------------------------------------------
  1905.  
  1906. --------------------------------------------------------------------------------
  1907. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 block diagrams
  1908. --------------------------------------------------------------------------------
  1909. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  1910. ------------- ---------------- -------------
  1911. Sstr3 9.2e-19 9332_[-11]_2987
  1912. Kiss1r 2.5e-18 5685_[+11]_1407
  1913. --------------------------------------------------------------------------------
  1914.  
  1915. --------------------------------------------------------------------------------
  1916. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 in BLOCKS format
  1917. --------------------------------------------------------------------------------
  1918. BL MOTIF RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA width=37 seqs=2
  1919. Sstr3 ( 9333) AACACAACCACAGGCAGCACCACCACAGCCGAGGCCA 1
  1920. Kiss1r ( 5686) GAGGCCTACAGAATGAGTTCCAGGACAGCCAGGGCTA 1
  1921. //
  1922.  
  1923. --------------------------------------------------------------------------------
  1924.  
  1925. --------------------------------------------------------------------------------
  1926. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 position-specific scoring matrix
  1927. --------------------------------------------------------------------------------
  1928. log-odds matrix: alength= 4 w= 37 n= 110092 bayes= 14.1633 E= 1.5e-004
  1929. 87 -765 113 -765
  1930. 187 -765 -765 -765
  1931. -765 113 113 -765
  1932. 87 -765 113 -765
  1933. -765 213 -765 -765
  1934. 87 113 -765 -765
  1935. 87 -765 -765 87
  1936. 87 113 -765 -765
  1937. -765 213 -765 -765
  1938. 187 -765 -765 -765
  1939. -765 113 113 -765
  1940. 187 -765 -765 -765
  1941. 87 -765 113 -765
  1942. -765 -765 113 87
  1943. -765 113 113 -765
  1944. 187 -765 -765 -765
  1945. -765 -765 213 -765
  1946. -765 113 -765 87
  1947. 87 -765 -765 87
  1948. -765 213 -765 -765
  1949. -765 213 -765 -765
  1950. 187 -765 -765 -765
  1951. -765 113 113 -765
  1952. -765 113 113 -765
  1953. 187 -765 -765 -765
  1954. -765 213 -765 -765
  1955. 187 -765 -765 -765
  1956. -765 -765 213 -765
  1957. -765 213 -765 -765
  1958. -765 213 -765 -765
  1959. 87 -765 113 -765
  1960. 87 -765 113 -765
  1961. -765 -765 213 -765
  1962. -765 -765 213 -765
  1963. -765 213 -765 -765
  1964. -765 113 -765 87
  1965. 187 -765 -765 -765
  1966. --------------------------------------------------------------------------------
  1967.  
  1968. --------------------------------------------------------------------------------
  1969. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 position-specific probability matrix
  1970. --------------------------------------------------------------------------------
  1971. letter-probability matrix: alength= 4 w= 37 nsites= 2 E= 1.5e-004
  1972. 0.500000 0.000000 0.500000 0.000000
  1973. 1.000000 0.000000 0.000000 0.000000
  1974. 0.000000 0.500000 0.500000 0.000000
  1975. 0.500000 0.000000 0.500000 0.000000
  1976. 0.000000 1.000000 0.000000 0.000000
  1977. 0.500000 0.500000 0.000000 0.000000
  1978. 0.500000 0.000000 0.000000 0.500000
  1979. 0.500000 0.500000 0.000000 0.000000
  1980. 0.000000 1.000000 0.000000 0.000000
  1981. 1.000000 0.000000 0.000000 0.000000
  1982. 0.000000 0.500000 0.500000 0.000000
  1983. 1.000000 0.000000 0.000000 0.000000
  1984. 0.500000 0.000000 0.500000 0.000000
  1985. 0.000000 0.000000 0.500000 0.500000
  1986. 0.000000 0.500000 0.500000 0.000000
  1987. 1.000000 0.000000 0.000000 0.000000
  1988. 0.000000 0.000000 1.000000 0.000000
  1989. 0.000000 0.500000 0.000000 0.500000
  1990. 0.500000 0.000000 0.000000 0.500000
  1991. 0.000000 1.000000 0.000000 0.000000
  1992. 0.000000 1.000000 0.000000 0.000000
  1993. 1.000000 0.000000 0.000000 0.000000
  1994. 0.000000 0.500000 0.500000 0.000000
  1995. 0.000000 0.500000 0.500000 0.000000
  1996. 1.000000 0.000000 0.000000 0.000000
  1997. 0.000000 1.000000 0.000000 0.000000
  1998. 1.000000 0.000000 0.000000 0.000000
  1999. 0.000000 0.000000 1.000000 0.000000
  2000. 0.000000 1.000000 0.000000 0.000000
  2001. 0.000000 1.000000 0.000000 0.000000
  2002. 0.500000 0.000000 0.500000 0.000000
  2003. 0.500000 0.000000 0.500000 0.000000
  2004. 0.000000 0.000000 1.000000 0.000000
  2005. 0.000000 0.000000 1.000000 0.000000
  2006. 0.000000 1.000000 0.000000 0.000000
  2007. 0.000000 0.500000 0.000000 0.500000
  2008. 1.000000 0.000000 0.000000 0.000000
  2009. --------------------------------------------------------------------------------
  2010.  
  2011. --------------------------------------------------------------------------------
  2012. Motif RASRCMWMCASARKSAGYWCCASSACAGCCRRGGCYA MEME-11 regular expression
  2013. --------------------------------------------------------------------------------
  2014. [AG]A[CG][AG]C[AC][AT][AC]CA[CG]A[AG][GT][CG]AG[CT][AT]CCA[CG][CG]ACAGCC[AG][AG]GGC[CT]A
  2015. --------------------------------------------------------------------------------
  2016.  
  2017.  
  2018.  
  2019.  
  2020. Time 6896.14 secs.
  2021.  
  2022. ********************************************************************************
  2023.  
  2024.  
  2025. ********************************************************************************
  2026. MOTIF YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 width = 40 sites = 4 llr = 149 E-value = 4.5e-003
  2027. ********************************************************************************
  2028. --------------------------------------------------------------------------------
  2029. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 Description
  2030. --------------------------------------------------------------------------------
  2031. Simplified A :8:83::8::3::8::3:::53:3:3333:::::3:3::3
  2032. pos.-specific C 5:3:3:5:::::::::3:::333::333::::8:33::::
  2033. probability G :38::a53aa8aa:aa5aaa35:8a5358a5a35355aa8
  2034. matrix T 5::35::::::::3::::::::8:::3:::5::5333:::
  2035.  
  2036. bits 2.1 * ** ** ** *** * * * **
  2037. 1.9 * ** ** ** *** * * * **
  2038. 1.7 * ** ** ** *** * * * **
  2039. 1.5 * ** ** ** *** * * * **
  2040. Relative 1.3 * * ***** ** *** ** ** ** ***
  2041. Entropy 1.1 **** *********** *** *** ****** ***
  2042. (53.7 bits) 0.9 **** *********** *** *** ****** ***
  2043. 0.6 **** *************** ***** ******* * ***
  2044. 0.4 ************************** ******* *****
  2045. 0.2 ************************** ******* *****
  2046. 0.0 ----------------------------------------
  2047.  
  2048. Multilevel CAGATGCAGGGGGAGGGGGGAGTGGGAGGGGGCGAGGGGG
  2049. consensus TGCTA GG A T A CACA ACAA T GTCCA A
  2050. sequence C C GC CGC GTT
  2051. T T
  2052. --------------------------------------------------------------------------------
  2053.  
  2054. --------------------------------------------------------------------------------
  2055. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 sites sorted by position p-value
  2056. --------------------------------------------------------------------------------
  2057. Sequence name Strand Start P-value Site
  2058. ------------- ------ ----- --------- ----------------------------------------
  2059. Htr6 - 13807 2.83e-18 GTGAGAGGTC CACATGGAGGGGGAGGCGGGGCTGGCCCGGTGCTCCGGGG GACAGTGGAC
  2060. Arl13b + 25705 3.90e-18 AACACCCTCA TAGAAGCAGGGGGAGGGGGGAGTGGATGGGGGCTTTTGGA GGAAGGGGTG
  2061. Sstr3 - 4554 7.06e-18 AGAGAGCCAG CAGACGCGGGGGGTGGGGGGAGCAGGAGGGTGCGGGAGGG GCCGGGAAGA
  2062. Kiss1r - 6873 1.33e-16 TTGCCTACAT TGGTTGGAGGAGGAGGAGGGCATGGGGAAGGGGGAGGGGG GTTGAGACAC
  2063. --------------------------------------------------------------------------------
  2064.  
  2065. --------------------------------------------------------------------------------
  2066. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 block diagrams
  2067. --------------------------------------------------------------------------------
  2068. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  2069. ------------- ---------------- -------------
  2070. Htr6 2.8e-18 13806_[-12]_1971
  2071. Arl13b 3.9e-18 25704_[+12]_28002
  2072. Sstr3 7.1e-18 4553_[-12]_7763
  2073. Kiss1r 1.3e-16 6872_[-12]_217
  2074. --------------------------------------------------------------------------------
  2075.  
  2076. --------------------------------------------------------------------------------
  2077. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 in BLOCKS format
  2078. --------------------------------------------------------------------------------
  2079. BL MOTIF YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG width=40 seqs=4
  2080. Htr6 ( 13807) CACATGGAGGGGGAGGCGGGGCTGGCCCGGTGCTCCGGGG 1
  2081. Arl13b ( 25705) TAGAAGCAGGGGGAGGGGGGAGTGGATGGGGGCTTTTGGA 1
  2082. Sstr3 ( 4554) CAGACGCGGGGGGTGGGGGGAGCAGGAGGGTGCGGGAGGG 1
  2083. Kiss1r ( 6873) TGGTTGGAGGAGGAGGAGGGCATGGGGAAGGGGGAGGGGG 1
  2084. //
  2085.  
  2086. --------------------------------------------------------------------------------
  2087.  
  2088. --------------------------------------------------------------------------------
  2089. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 position-specific scoring matrix
  2090. --------------------------------------------------------------------------------
  2091. log-odds matrix: alength= 4 w= 40 n= 110068 bayes= 14.0699 E= 4.5e-003
  2092. -865 113 -865 87
  2093. 146 -865 14 -865
  2094. -865 14 172 -865
  2095. 146 -865 -865 -12
  2096. -12 14 -865 87
  2097. -865 -865 213 -865
  2098. -865 113 113 -865
  2099. 146 -865 14 -865
  2100. -865 -865 213 -865
  2101. -865 -865 213 -865
  2102. -12 -865 172 -865
  2103. -865 -865 213 -865
  2104. -865 -865 213 -865
  2105. 146 -865 -865 -12
  2106. -865 -865 213 -865
  2107. -865 -865 213 -865
  2108. -12 14 113 -865
  2109. -865 -865 213 -865
  2110. -865 -865 213 -865
  2111. -865 -865 213 -865
  2112. 87 14 14 -865
  2113. -12 14 113 -865
  2114. -865 14 -865 146
  2115. -12 -865 172 -865
  2116. -865 -865 213 -865
  2117. -12 14 113 -865
  2118. -12 14 14 -12
  2119. -12 14 113 -865
  2120. -12 -865 172 -865
  2121. -865 -865 213 -865
  2122. -865 -865 113 87
  2123. -865 -865 213 -865
  2124. -865 172 14 -865
  2125. -865 -865 113 87
  2126. -12 14 14 -12
  2127. -865 14 113 -12
  2128. -12 -865 113 -12
  2129. -865 -865 213 -865
  2130. -865 -865 213 -865
  2131. -12 -865 172 -865
  2132. --------------------------------------------------------------------------------
  2133.  
  2134. --------------------------------------------------------------------------------
  2135. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 position-specific probability matrix
  2136. --------------------------------------------------------------------------------
  2137. letter-probability matrix: alength= 4 w= 40 nsites= 4 E= 4.5e-003
  2138. 0.000000 0.500000 0.000000 0.500000
  2139. 0.750000 0.000000 0.250000 0.000000
  2140. 0.000000 0.250000 0.750000 0.000000
  2141. 0.750000 0.000000 0.000000 0.250000
  2142. 0.250000 0.250000 0.000000 0.500000
  2143. 0.000000 0.000000 1.000000 0.000000
  2144. 0.000000 0.500000 0.500000 0.000000
  2145. 0.750000 0.000000 0.250000 0.000000
  2146. 0.000000 0.000000 1.000000 0.000000
  2147. 0.000000 0.000000 1.000000 0.000000
  2148. 0.250000 0.000000 0.750000 0.000000
  2149. 0.000000 0.000000 1.000000 0.000000
  2150. 0.000000 0.000000 1.000000 0.000000
  2151. 0.750000 0.000000 0.000000 0.250000
  2152. 0.000000 0.000000 1.000000 0.000000
  2153. 0.000000 0.000000 1.000000 0.000000
  2154. 0.250000 0.250000 0.500000 0.000000
  2155. 0.000000 0.000000 1.000000 0.000000
  2156. 0.000000 0.000000 1.000000 0.000000
  2157. 0.000000 0.000000 1.000000 0.000000
  2158. 0.500000 0.250000 0.250000 0.000000
  2159. 0.250000 0.250000 0.500000 0.000000
  2160. 0.000000 0.250000 0.000000 0.750000
  2161. 0.250000 0.000000 0.750000 0.000000
  2162. 0.000000 0.000000 1.000000 0.000000
  2163. 0.250000 0.250000 0.500000 0.000000
  2164. 0.250000 0.250000 0.250000 0.250000
  2165. 0.250000 0.250000 0.500000 0.000000
  2166. 0.250000 0.000000 0.750000 0.000000
  2167. 0.000000 0.000000 1.000000 0.000000
  2168. 0.000000 0.000000 0.500000 0.500000
  2169. 0.000000 0.000000 1.000000 0.000000
  2170. 0.000000 0.750000 0.250000 0.000000
  2171. 0.000000 0.000000 0.500000 0.500000
  2172. 0.250000 0.250000 0.250000 0.250000
  2173. 0.000000 0.250000 0.500000 0.250000
  2174. 0.250000 0.000000 0.500000 0.250000
  2175. 0.000000 0.000000 1.000000 0.000000
  2176. 0.000000 0.000000 1.000000 0.000000
  2177. 0.250000 0.000000 0.750000 0.000000
  2178. --------------------------------------------------------------------------------
  2179.  
  2180. --------------------------------------------------------------------------------
  2181. Motif YAGAHGSAGGGGGAGGVGGGVVTGGVNVGGKGCKNBDGGG MEME-12 regular expression
  2182. --------------------------------------------------------------------------------
  2183. [CT][AG][GC][AT][TAC]G[CG][AG]GG[GA]GG[AT]GG[GAC]GGG[ACG][GAC][TC][GA]G[GAC][ACGT][GAC][GA]G[GT]G[CG][GT][ACGT][GCT][GAT]GG[GA]
  2184. --------------------------------------------------------------------------------
  2185.  
  2186.  
  2187.  
  2188.  
  2189. Time 7511.61 secs.
  2190.  
  2191. ********************************************************************************
  2192.  
  2193.  
  2194. ********************************************************************************
  2195. MOTIF SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 width = 41 sites = 7 llr = 212 E-value = 1.0e-002
  2196. ********************************************************************************
  2197. --------------------------------------------------------------------------------
  2198. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 Description
  2199. --------------------------------------------------------------------------------
  2200. Simplified A ::::4::::::11:::14:::434:4:1:313::1:3::::
  2201. pos.-specific C 496661191:a737476:a9a376719:6193a63a14774
  2202. probability G 4113:111:9:::1:3:4:1::::111:43::::1::313:
  2203. matrix T 1:31:77:91:1616:31:::3::13:9:3:4:44:631:6
  2204.  
  2205. bits 2.1 * * * * *
  2206. 1.9 * * * * *
  2207. 1.7 * * * * *
  2208. 1.5 * * ** *** * * * *
  2209. Relative 1.3 * **** * *** * ** * * * *
  2210. Entropy 1.1 * * **** ** *** ** *** * ** * **
  2211. (43.8 bits) 0.9 * ******** *** *** *** *** * ** * ***
  2212. 0.6 ********************* *** *** * ** ** ***
  2213. 0.4 ************************* *** **** ******
  2214. 0.2 ***************************** ***********
  2215. 0.0 -----------------------------------------
  2216.  
  2217. Multilevel CCCCCTTCTGCCTCTCCACCCACCCACTCACTCCTCTCCCT
  2218. consensus G TGA C CGTG CAA T GG A TC AG GC
  2219. sequence T T C T
  2220.  
  2221. --------------------------------------------------------------------------------
  2222.  
  2223. --------------------------------------------------------------------------------
  2224. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 sites sorted by position p-value
  2225. --------------------------------------------------------------------------------
  2226. Sequence name Strand Start P-value Site
  2227. ------------- ------ ----- --------- -----------------------------------------
  2228. Sstr3 + 4789 7.80e-19 CCTTACTCCC CCTCATTCTGCCTTTCCACCCACACACTGTCTCCTCTCCCT CTCCTTTCTC
  2229. Kiss1r - 3307 1.02e-15 CCCAGAACAT GCCCATTGTGCCTCCCCGCCCTCCCCCAGACTCTCCAGCGT CCTGATTCCA
  2230. Mc4r - 54 4.25e-15 ACTGCTGGGA GCCGCGTCTGCATCTGCGCGCCCACACTCACACCGCAGCCT CTCAGAAGTT
  2231. Mchr1 - 93 7.86e-15 CCGCCTGGCA GCCTCTGCTGCCTCTGAGCCCAACTGCTCGCCCCACTCCCT CCTTCCCAGC
  2232. Htr6 + 14876 3.08e-14 AGTGTCCCTC CCTCCTTCTTCCAGCCTTCCCTCCCTCTCTCCCTCCCTCCC TCCCTCCCTC
  2233. Arl13b - 37357 5.14e-14 CCTATTACCC CCCCCCCCCGCTCCCCTACCCACCCACTCCCTCTTCTTGGC CCTGGAGTTC
  2234. Npy2r + 510 1.02e-12 TAGCCCAGAG TGGGATTCTGCCCCTCCACCCCAAGTGTGGAACCTCTCTCC AGCCCACACC
  2235. --------------------------------------------------------------------------------
  2236.  
  2237. --------------------------------------------------------------------------------
  2238. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 block diagrams
  2239. --------------------------------------------------------------------------------
  2240. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  2241. ------------- ---------------- -------------
  2242. Sstr3 7.8e-19 4788_[+13]_7527
  2243. Kiss1r 1e-15 3306_[-13]_3782
  2244. Mc4r 4.3e-15 53_[-13]_2689
  2245. Mchr1 7.9e-15 92_[-13]_3333
  2246. Htr6 3.1e-14 14875_[+13]_901
  2247. Arl13b 5.1e-14 37356_[-13]_16349
  2248. Npy2r 1e-12 509_[+13]_10057
  2249. --------------------------------------------------------------------------------
  2250.  
  2251. --------------------------------------------------------------------------------
  2252. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 in BLOCKS format
  2253. --------------------------------------------------------------------------------
  2254. BL MOTIF SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY width=41 seqs=7
  2255. Sstr3 ( 4789) CCTCATTCTGCCTTTCCACCCACACACTGTCTCCTCTCCCT 1
  2256. Kiss1r ( 3307) GCCCATTGTGCCTCCCCGCCCTCCCCCAGACTCTCCAGCGT 1
  2257. Mc4r ( 54) GCCGCGTCTGCATCTGCGCGCCCACACTCACACCGCAGCCT 1
  2258. Mchr1 ( 93) GCCTCTGCTGCCTCTGAGCCCAACTGCTCGCCCCACTCCCT 1
  2259. Htr6 ( 14876) CCTCCTTCTTCCAGCCTTCCCTCCCTCTCTCCCTCCCTCCC 1
  2260. Arl13b ( 37357) CCCCCCCCCGCTCCCCTACCCACCCACTCCCTCTTCTTGGC 1
  2261. Npy2r ( 510) TGGGATTCTGCCCCTCCACCCCAAGTGTGGAACCTCTCTCC 1
  2262. //
  2263.  
  2264. --------------------------------------------------------------------------------
  2265.  
  2266. --------------------------------------------------------------------------------
  2267. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 position-specific scoring matrix
  2268. --------------------------------------------------------------------------------
  2269. log-odds matrix: alength= 4 w= 41 n= 110060 bayes= 13.9405 E= 1.0e-002
  2270. -945 91 91 -93
  2271. -945 191 -67 -945
  2272. -945 133 -67 7
  2273. -945 133 33 -93
  2274. 65 133 -945 -945
  2275. -945 -67 -67 139
  2276. -945 -67 -67 139
  2277. -945 191 -67 -945
  2278. -945 -67 -945 165
  2279. -945 -945 191 -93
  2280. -945 213 -945 -945
  2281. -93 165 -945 -93
  2282. -93 33 -945 107
  2283. -945 165 -67 -93
  2284. -945 91 -945 107
  2285. -945 165 33 -945
  2286. -93 133 -945 7
  2287. 65 -945 91 -93
  2288. -945 213 -945 -945
  2289. -945 191 -67 -945
  2290. -945 213 -945 -945
  2291. 65 33 -945 7
  2292. 7 165 -945 -945
  2293. 65 133 -945 -945
  2294. -945 165 -67 -93
  2295. 65 -67 -67 7
  2296. -945 191 -67 -945
  2297. -93 -945 -945 165
  2298. -945 133 91 -945
  2299. 7 -67 33 7
  2300. -93 191 -945 -945
  2301. 7 33 -945 65
  2302. -945 213 -945 -945
  2303. -945 133 -945 65
  2304. -93 33 -67 65
  2305. -945 213 -945 -945
  2306. 7 -67 -945 107
  2307. -945 91 33 7
  2308. -945 165 -67 -93
  2309. -945 165 33 -945
  2310. -945 91 -945 107
  2311. --------------------------------------------------------------------------------
  2312.  
  2313. --------------------------------------------------------------------------------
  2314. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 position-specific probability matrix
  2315. --------------------------------------------------------------------------------
  2316. letter-probability matrix: alength= 4 w= 41 nsites= 7 E= 1.0e-002
  2317. 0.000000 0.428571 0.428571 0.142857
  2318. 0.000000 0.857143 0.142857 0.000000
  2319. 0.000000 0.571429 0.142857 0.285714
  2320. 0.000000 0.571429 0.285714 0.142857
  2321. 0.428571 0.571429 0.000000 0.000000
  2322. 0.000000 0.142857 0.142857 0.714286
  2323. 0.000000 0.142857 0.142857 0.714286
  2324. 0.000000 0.857143 0.142857 0.000000
  2325. 0.000000 0.142857 0.000000 0.857143
  2326. 0.000000 0.000000 0.857143 0.142857
  2327. 0.000000 1.000000 0.000000 0.000000
  2328. 0.142857 0.714286 0.000000 0.142857
  2329. 0.142857 0.285714 0.000000 0.571429
  2330. 0.000000 0.714286 0.142857 0.142857
  2331. 0.000000 0.428571 0.000000 0.571429
  2332. 0.000000 0.714286 0.285714 0.000000
  2333. 0.142857 0.571429 0.000000 0.285714
  2334. 0.428571 0.000000 0.428571 0.142857
  2335. 0.000000 1.000000 0.000000 0.000000
  2336. 0.000000 0.857143 0.142857 0.000000
  2337. 0.000000 1.000000 0.000000 0.000000
  2338. 0.428571 0.285714 0.000000 0.285714
  2339. 0.285714 0.714286 0.000000 0.000000
  2340. 0.428571 0.571429 0.000000 0.000000
  2341. 0.000000 0.714286 0.142857 0.142857
  2342. 0.428571 0.142857 0.142857 0.285714
  2343. 0.000000 0.857143 0.142857 0.000000
  2344. 0.142857 0.000000 0.000000 0.857143
  2345. 0.000000 0.571429 0.428571 0.000000
  2346. 0.285714 0.142857 0.285714 0.285714
  2347. 0.142857 0.857143 0.000000 0.000000
  2348. 0.285714 0.285714 0.000000 0.428571
  2349. 0.000000 1.000000 0.000000 0.000000
  2350. 0.000000 0.571429 0.000000 0.428571
  2351. 0.142857 0.285714 0.142857 0.428571
  2352. 0.000000 1.000000 0.000000 0.000000
  2353. 0.285714 0.142857 0.000000 0.571429
  2354. 0.000000 0.428571 0.285714 0.285714
  2355. 0.000000 0.714286 0.142857 0.142857
  2356. 0.000000 0.714286 0.285714 0.000000
  2357. 0.000000 0.428571 0.000000 0.571429
  2358. --------------------------------------------------------------------------------
  2359.  
  2360. --------------------------------------------------------------------------------
  2361. Motif SCYSMTTCTGCCYCYCYRCCCHCMCWCTSNCHCYYCWBCCY MEME-13 regular expression
  2362. --------------------------------------------------------------------------------
  2363. [CG]C[CT][CG][CA]TTCTGCC[TC]C[TC][CG][CT][AG]CCC[ACT][CA][CA]C[AT]CT[CG][AGT]C[TAC]C[CT][TC]C[TA][CGT]C[CG][TC]
  2364. --------------------------------------------------------------------------------
  2365.  
  2366.  
  2367.  
  2368.  
  2369. Time 8126.64 secs.
  2370.  
  2371. ********************************************************************************
  2372.  
  2373.  
  2374. ********************************************************************************
  2375. MOTIF RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 width = 40 sites = 3 llr = 147 E-value = 1.5e-001
  2376. ********************************************************************************
  2377. --------------------------------------------------------------------------------
  2378. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 Description
  2379. --------------------------------------------------------------------------------
  2380. Simplified A 7:a37:::a::::::::::::::::37:::::3::a::aa
  2381. pos.-specific C ::::::7a:7a::aa:a::aa:aa3:::::a:::::3:::
  2382. probability G 3a:73:::::::a:::::a::::::7:a:7::7aa:::::
  2383. matrix T :::::a3::3:a:::a:a:::a::7:3:a3:a::::7a::
  2384.  
  2385. bits 2.1 * * * *** * *** ** * * **
  2386. 1.9 ** * ** ************** ** ** *** ***
  2387. 1.7 ** * ** ************** ** ** *** ***
  2388. 1.5 ** * ** ************** ** ** *** ***
  2389. Relative 1.3 ** * ** ************** ** ** *** ***
  2390. Entropy 1.1 ************************** *************
  2391. (70.5 bits) 0.9 ****************************************
  2392. 0.6 ****************************************
  2393. 0.4 ****************************************
  2394. 0.2 ****************************************
  2395. 0.0 ----------------------------------------
  2396.  
  2397. Multilevel AGAGATCCACCTGCCTCTGCCTCCTGAGTGCTGGGATTAA
  2398. consensus G AG T T CAT T A C
  2399. sequence
  2400.  
  2401. --------------------------------------------------------------------------------
  2402.  
  2403. --------------------------------------------------------------------------------
  2404. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 sites sorted by position p-value
  2405. --------------------------------------------------------------------------------
  2406. Sequence name Strand Start P-value Site
  2407. ------------- ------ ----- --------- ----------------------------------------
  2408. Kiss1r + 6025 6.66e-23 CCTCGACTTT GGAGATCCACCTGCCTCTGCCTCCTGTGTGCTAGGATTAA AGGGGTGTGC
  2409. Arl13b - 49683 1.99e-22 CCTTGAATTC AGAAGTCCACCTGCCTCTGCCTCCCAAGTGCTGGGATTAA AGGCAAGTGC
  2410. Htr6 + 4400 3.02e-22 TCGAACTCAC AGAGATTCATCTGCCTCTGCCTCCTGAGTTCTGGGACTAA ATGTGTGTGC
  2411. --------------------------------------------------------------------------------
  2412.  
  2413. --------------------------------------------------------------------------------
  2414. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 block diagrams
  2415. --------------------------------------------------------------------------------
  2416. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  2417. ------------- ---------------- -------------
  2418. Kiss1r 6.7e-23 6024_[+14]_1065
  2419. Arl13b 2e-22 49682_[-14]_4024
  2420. Htr6 3e-22 4399_[+14]_11378
  2421. --------------------------------------------------------------------------------
  2422.  
  2423. --------------------------------------------------------------------------------
  2424. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 in BLOCKS format
  2425. --------------------------------------------------------------------------------
  2426. BL MOTIF RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA width=40 seqs=3
  2427. Kiss1r ( 6025) GGAGATCCACCTGCCTCTGCCTCCTGTGTGCTAGGATTAA 1
  2428. Arl13b ( 49683) AGAAGTCCACCTGCCTCTGCCTCCCAAGTGCTGGGATTAA 1
  2429. Htr6 ( 4400) AGAGATTCATCTGCCTCTGCCTCCTGAGTTCTGGGACTAA 1
  2430. //
  2431.  
  2432. --------------------------------------------------------------------------------
  2433.  
  2434. --------------------------------------------------------------------------------
  2435. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 position-specific scoring matrix
  2436. --------------------------------------------------------------------------------
  2437. log-odds matrix: alength= 4 w= 40 n= 110068 bayes= 14.822 E= 1.5e-001
  2438. 129 -823 55 -823
  2439. -823 -823 213 -823
  2440. 187 -823 -823 -823
  2441. 29 -823 155 -823
  2442. 129 -823 55 -823
  2443. -823 -823 -823 187
  2444. -823 155 -823 29
  2445. -823 213 -823 -823
  2446. 187 -823 -823 -823
  2447. -823 155 -823 29
  2448. -823 213 -823 -823
  2449. -823 -823 -823 187
  2450. -823 -823 213 -823
  2451. -823 213 -823 -823
  2452. -823 213 -823 -823
  2453. -823 -823 -823 187
  2454. -823 213 -823 -823
  2455. -823 -823 -823 187
  2456. -823 -823 213 -823
  2457. -823 213 -823 -823
  2458. -823 213 -823 -823
  2459. -823 -823 -823 187
  2460. -823 213 -823 -823
  2461. -823 213 -823 -823
  2462. -823 55 -823 129
  2463. 29 -823 155 -823
  2464. 129 -823 -823 29
  2465. -823 -823 213 -823
  2466. -823 -823 -823 187
  2467. -823 -823 155 29
  2468. -823 213 -823 -823
  2469. -823 -823 -823 187
  2470. 29 -823 155 -823
  2471. -823 -823 213 -823
  2472. -823 -823 213 -823
  2473. 187 -823 -823 -823
  2474. -823 55 -823 129
  2475. -823 -823 -823 187
  2476. 187 -823 -823 -823
  2477. 187 -823 -823 -823
  2478. --------------------------------------------------------------------------------
  2479.  
  2480. --------------------------------------------------------------------------------
  2481. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 position-specific probability matrix
  2482. --------------------------------------------------------------------------------
  2483. letter-probability matrix: alength= 4 w= 40 nsites= 3 E= 1.5e-001
  2484. 0.666667 0.000000 0.333333 0.000000
  2485. 0.000000 0.000000 1.000000 0.000000
  2486. 1.000000 0.000000 0.000000 0.000000
  2487. 0.333333 0.000000 0.666667 0.000000
  2488. 0.666667 0.000000 0.333333 0.000000
  2489. 0.000000 0.000000 0.000000 1.000000
  2490. 0.000000 0.666667 0.000000 0.333333
  2491. 0.000000 1.000000 0.000000 0.000000
  2492. 1.000000 0.000000 0.000000 0.000000
  2493. 0.000000 0.666667 0.000000 0.333333
  2494. 0.000000 1.000000 0.000000 0.000000
  2495. 0.000000 0.000000 0.000000 1.000000
  2496. 0.000000 0.000000 1.000000 0.000000
  2497. 0.000000 1.000000 0.000000 0.000000
  2498. 0.000000 1.000000 0.000000 0.000000
  2499. 0.000000 0.000000 0.000000 1.000000
  2500. 0.000000 1.000000 0.000000 0.000000
  2501. 0.000000 0.000000 0.000000 1.000000
  2502. 0.000000 0.000000 1.000000 0.000000
  2503. 0.000000 1.000000 0.000000 0.000000
  2504. 0.000000 1.000000 0.000000 0.000000
  2505. 0.000000 0.000000 0.000000 1.000000
  2506. 0.000000 1.000000 0.000000 0.000000
  2507. 0.000000 1.000000 0.000000 0.000000
  2508. 0.000000 0.333333 0.000000 0.666667
  2509. 0.333333 0.000000 0.666667 0.000000
  2510. 0.666667 0.000000 0.000000 0.333333
  2511. 0.000000 0.000000 1.000000 0.000000
  2512. 0.000000 0.000000 0.000000 1.000000
  2513. 0.000000 0.000000 0.666667 0.333333
  2514. 0.000000 1.000000 0.000000 0.000000
  2515. 0.000000 0.000000 0.000000 1.000000
  2516. 0.333333 0.000000 0.666667 0.000000
  2517. 0.000000 0.000000 1.000000 0.000000
  2518. 0.000000 0.000000 1.000000 0.000000
  2519. 1.000000 0.000000 0.000000 0.000000
  2520. 0.000000 0.333333 0.000000 0.666667
  2521. 0.000000 0.000000 0.000000 1.000000
  2522. 1.000000 0.000000 0.000000 0.000000
  2523. 1.000000 0.000000 0.000000 0.000000
  2524. --------------------------------------------------------------------------------
  2525.  
  2526. --------------------------------------------------------------------------------
  2527. Motif RGARRTYCAYCTGCCTCTGCCTCCYRWGTKCTRGGAYTAA MEME-14 regular expression
  2528. --------------------------------------------------------------------------------
  2529. [AG]GA[GA][AG]T[CT]CA[CT]CTGCCTCTGCCTCC[TC][GA][AT]GT[GT]CT[GA]GGA[TC]TAA
  2530. --------------------------------------------------------------------------------
  2531.  
  2532.  
  2533.  
  2534.  
  2535. Time 8723.28 secs.
  2536.  
  2537. ********************************************************************************
  2538.  
  2539.  
  2540. ********************************************************************************
  2541. MOTIF STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 width = 50 sites = 5 llr = 215 E-value = 5.0e-001
  2542. ********************************************************************************
  2543. --------------------------------------------------------------------------------
  2544. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 Description
  2545. --------------------------------------------------------------------------------
  2546. Simplified A :::4::8::22:2:::86:::a::62:28:a2:6::::4:::44:682::
  2547. pos.-specific C 4:46:6:82::68:::226:6:642:2::::46:::a2::88264428:8
  2548. probability G 6::::422:84::2a8:2424:42:28:2a:4:4a6::482:::6::::2
  2549. matrix T :a6:a:::8:44:8:2:::8:::426:8::::4::4:822:24:::::a:
  2550.  
  2551. bits 2.1 * * * *
  2552. 1.9 * * * * ** * * *
  2553. 1.7 * * * * ** * * *
  2554. 1.5 * * * * * * ** * * * **
  2555. Relative 1.3 * * **** ***** * * * *** * ** *** ****
  2556. Entropy 1.1 ********** ****** ***** ***** ****** *** *******
  2557. (62.0 bits) 0.9 ********** ****** ***** ***** ****** *** *******
  2558. 0.6 ********** ************ ************** *** *******
  2559. 0.4 **************************************************
  2560. 0.2 **************************************************
  2561. 0.0 --------------------------------------------------
  2562.  
  2563. Multilevel GTTCTCACTGGCCTGGAACTCACCATGTAGACCAGGCTAGCCACGAACTC
  2564. consensus C CA GGGCATTAG TCCGGG GTCACAG GTG T CGTGTTACCCA G
  2565. sequence A G GTG A T C
  2566.  
  2567. --------------------------------------------------------------------------------
  2568.  
  2569. --------------------------------------------------------------------------------
  2570. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 sites sorted by position p-value
  2571. --------------------------------------------------------------------------------
  2572. Sequence name Strand Start P-value Site
  2573. ------------- ------ ----- --------- --------------------------------------------------
  2574. Htr6 + 4348 1.18e-25 GTTTCTCTGT GTCATCACTGTCCTGGAACTCAGTCTGTAGACCAGGCTGGCCTCGAACTC ACAGAGATTC
  2575. Arl13b + 19322 6.10e-25 TCTCTGTGTA GTTCTGGCTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAACTC AGAAGTCCGC
  2576. Kiss1r + 6381 2.97e-20 AGTAGGTGTA GTTCTGAGTGACAGGGAGGTGACCATGTAGAGCAGGCTAGCCCAGACCTC ACAGTAATCT
  2577. Npy2r + 5910 1.23e-18 TGAGACAGGC CTTCTCACTGGTCTGGAAGTCACCAACTAGAATGGTCTTTCTAACCAATG AGCCTCACCA
  2578. Sstr3 + 8333 2.88e-17 ATGCAGATTT CTCATCACCAGTCTGTCCCGGAGGAGGAGGAGTGGTCCAGGCACCCACTC ACATTCACAC
  2579. --------------------------------------------------------------------------------
  2580.  
  2581. --------------------------------------------------------------------------------
  2582. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 block diagrams
  2583. --------------------------------------------------------------------------------
  2584. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  2585. ------------- ---------------- -------------
  2586. Htr6 1.2e-25 4347_[+15]_11420
  2587. Arl13b 6.1e-25 19321_[+15]_34375
  2588. Kiss1r 3e-20 6380_[+15]_699
  2589. Npy2r 1.2e-18 5909_[+15]_4648
  2590. Sstr3 2.9e-17 8332_[+15]_3974
  2591. --------------------------------------------------------------------------------
  2592.  
  2593. --------------------------------------------------------------------------------
  2594. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 in BLOCKS format
  2595. --------------------------------------------------------------------------------
  2596. BL MOTIF STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC width=50 seqs=5
  2597. Htr6 ( 4348) GTCATCACTGTCCTGGAACTCAGTCTGTAGACCAGGCTGGCCTCGAACTC 1
  2598. Arl13b ( 19322) GTTCTGGCTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAACTC 1
  2599. Kiss1r ( 6381) GTTCTGAGTGACAGGGAGGTGACCATGTAGAGCAGGCTAGCCCAGACCTC 1
  2600. Npy2r ( 5910) CTTCTCACTGGTCTGGAAGTCACCAACTAGAATGGTCTTTCTAACCAATG 1
  2601. Sstr3 ( 8333) CTCATCACCAGTCTGTCCCGGAGGAGGAGGAGTGGTCCAGGCACCCACTC 1
  2602. //
  2603.  
  2604. --------------------------------------------------------------------------------
  2605.  
  2606. --------------------------------------------------------------------------------
  2607. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 position-specific scoring matrix
  2608. --------------------------------------------------------------------------------
  2609. log-odds matrix: alength= 4 w= 50 n= 109988 bayes= 15.3684 E= 5.0e-001
  2610. -897 81 140 -897
  2611. -897 -897 -897 187
  2612. -897 81 -897 114
  2613. 55 140 -897 -897
  2614. -897 -897 -897 187
  2615. -897 140 81 -897
  2616. 155 -897 -19 -897
  2617. -897 181 -19 -897
  2618. -897 -19 -897 155
  2619. -44 -897 181 -897
  2620. -44 -897 81 55
  2621. -897 140 -897 55
  2622. -44 181 -897 -897
  2623. -897 -897 -19 155
  2624. -897 -897 213 -897
  2625. -897 -897 181 -44
  2626. 155 -19 -897 -897
  2627. 114 -19 -19 -897
  2628. -897 140 81 -897
  2629. -897 -897 -19 155
  2630. -897 140 81 -897
  2631. 187 -897 -897 -897
  2632. -897 140 81 -897
  2633. -897 81 -19 55
  2634. 114 -19 -897 -44
  2635. -44 -897 -19 114
  2636. -897 -19 181 -897
  2637. -44 -897 -897 155
  2638. 155 -897 -19 -897
  2639. -897 -897 213 -897
  2640. 187 -897 -897 -897
  2641. -44 81 81 -897
  2642. -897 140 -897 55
  2643. 114 -897 81 -897
  2644. -897 -897 213 -897
  2645. -897 -897 140 55
  2646. -897 213 -897 -897
  2647. -897 -19 -897 155
  2648. 55 -897 81 -44
  2649. -897 -897 181 -44
  2650. -897 181 -19 -897
  2651. -897 181 -897 -44
  2652. 55 -19 -897 55
  2653. 55 140 -897 -897
  2654. -897 81 140 -897
  2655. 114 81 -897 -897
  2656. 155 -19 -897 -897
  2657. -44 181 -897 -897
  2658. -897 -897 -897 187
  2659. -897 181 -19 -897
  2660. --------------------------------------------------------------------------------
  2661.  
  2662. --------------------------------------------------------------------------------
  2663. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 position-specific probability matrix
  2664. --------------------------------------------------------------------------------
  2665. letter-probability matrix: alength= 4 w= 50 nsites= 5 E= 5.0e-001
  2666. 0.000000 0.400000 0.600000 0.000000
  2667. 0.000000 0.000000 0.000000 1.000000
  2668. 0.000000 0.400000 0.000000 0.600000
  2669. 0.400000 0.600000 0.000000 0.000000
  2670. 0.000000 0.000000 0.000000 1.000000
  2671. 0.000000 0.600000 0.400000 0.000000
  2672. 0.800000 0.000000 0.200000 0.000000
  2673. 0.000000 0.800000 0.200000 0.000000
  2674. 0.000000 0.200000 0.000000 0.800000
  2675. 0.200000 0.000000 0.800000 0.000000
  2676. 0.200000 0.000000 0.400000 0.400000
  2677. 0.000000 0.600000 0.000000 0.400000
  2678. 0.200000 0.800000 0.000000 0.000000
  2679. 0.000000 0.000000 0.200000 0.800000
  2680. 0.000000 0.000000 1.000000 0.000000
  2681. 0.000000 0.000000 0.800000 0.200000
  2682. 0.800000 0.200000 0.000000 0.000000
  2683. 0.600000 0.200000 0.200000 0.000000
  2684. 0.000000 0.600000 0.400000 0.000000
  2685. 0.000000 0.000000 0.200000 0.800000
  2686. 0.000000 0.600000 0.400000 0.000000
  2687. 1.000000 0.000000 0.000000 0.000000
  2688. 0.000000 0.600000 0.400000 0.000000
  2689. 0.000000 0.400000 0.200000 0.400000
  2690. 0.600000 0.200000 0.000000 0.200000
  2691. 0.200000 0.000000 0.200000 0.600000
  2692. 0.000000 0.200000 0.800000 0.000000
  2693. 0.200000 0.000000 0.000000 0.800000
  2694. 0.800000 0.000000 0.200000 0.000000
  2695. 0.000000 0.000000 1.000000 0.000000
  2696. 1.000000 0.000000 0.000000 0.000000
  2697. 0.200000 0.400000 0.400000 0.000000
  2698. 0.000000 0.600000 0.000000 0.400000
  2699. 0.600000 0.000000 0.400000 0.000000
  2700. 0.000000 0.000000 1.000000 0.000000
  2701. 0.000000 0.000000 0.600000 0.400000
  2702. 0.000000 1.000000 0.000000 0.000000
  2703. 0.000000 0.200000 0.000000 0.800000
  2704. 0.400000 0.000000 0.400000 0.200000
  2705. 0.000000 0.000000 0.800000 0.200000
  2706. 0.000000 0.800000 0.200000 0.000000
  2707. 0.000000 0.800000 0.000000 0.200000
  2708. 0.400000 0.200000 0.000000 0.400000
  2709. 0.400000 0.600000 0.000000 0.000000
  2710. 0.000000 0.400000 0.600000 0.000000
  2711. 0.600000 0.400000 0.000000 0.000000
  2712. 0.800000 0.200000 0.000000 0.000000
  2713. 0.200000 0.800000 0.000000 0.000000
  2714. 0.000000 0.000000 0.000000 1.000000
  2715. 0.000000 0.800000 0.200000 0.000000
  2716. --------------------------------------------------------------------------------
  2717.  
  2718. --------------------------------------------------------------------------------
  2719. Motif STYMTSACTGDYCTGGAASTSASBATGTAGAVYRGKCTDGCCHMSMACTC MEME-15 regular expression
  2720. --------------------------------------------------------------------------------
  2721. [GC]T[TC][CA]T[CG][AG][CG][TC][GA][GTA][CT][CA][TG]G[GT][AC][ACG][CG][TG][CG]A[CG][CTG][ACT][TAG][GC][TA][AG]GA[CGA][CT][AG]G[GT]C[TC][AGT][GT][CG][CT][ATC][CA][GC][AC][AC][CA]T[CG]
  2722. --------------------------------------------------------------------------------
  2723.  
  2724.  
  2725.  
  2726.  
  2727. Time 9317.52 secs.
  2728.  
  2729. ********************************************************************************
  2730.  
  2731.  
  2732. ********************************************************************************
  2733. MOTIF GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 width = 41 sites = 4 llr = 167 E-value = 3.1e+000
  2734. ********************************************************************************
  2735. --------------------------------------------------------------------------------
  2736. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 Description
  2737. --------------------------------------------------------------------------------
  2738. Simplified A 3::83:3:a8:3:a::3::::::3a838::a::35::::::
  2739. pos.-specific C ::::383:::a5a::::8a38::3::::3a::53::::5:a
  2740. probability G 8aa:5::a:3::::aa:3:3::a3:3838::a3:5a3a3::
  2741. matrix T :::3:35::::3::::8::53a:3::::::::35::8:3a:
  2742.  
  2743. bits 2.1 ** * * * ** * * * * * * *
  2744. 1.9 ** ** * **** * ** * *** * * **
  2745. 1.7 ** ** * **** * ** * *** * * **
  2746. 1.5 ** ** * **** * ** * *** * * **
  2747. Relative 1.3 *** * ** * **** ** *** * * **** * * **
  2748. Entropy 1.1 **** * **** ******* *** ******** **** **
  2749. (60.1 bits) 0.9 **** * **** ******* *** ******** **** **
  2750. 0.6 ****** **** ******* *** ********* *******
  2751. 0.4 *********************** *****************
  2752. 0.2 *********************** *****************
  2753. 0.0 -----------------------------------------
  2754.  
  2755. Multilevel GGGAGCTGAACCCAGGTCCTCTGAAAGAGCAGCTAGTGCTC
  2756. consensus A TATA G A AG CT C GAGC GAG G G
  2757. sequence C C T G G TC T
  2758. T
  2759. --------------------------------------------------------------------------------
  2760.  
  2761. --------------------------------------------------------------------------------
  2762. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 sites sorted by position p-value
  2763. --------------------------------------------------------------------------------
  2764. Sequence name Strand Start P-value Site
  2765. ------------- ------ ----- --------- -----------------------------------------
  2766. Kiss1r + 3107 3.97e-22 TGTGGATGCG AGGAGCTGAACCCAGGTCCTCTGAAAGAGCAGCTGGTGTTC TAACCCCTGA
  2767. Htr6 + 9571 1.49e-21 TGTGGGTGCT GGGACCCGAACCCAGGTCCTCTGTAAGAGCAGGAAGTGCTC TTAACCAATG
  2768. Arl13b + 11161 1.02e-19 TGTAGTTGCT GGGAATTGAACTCAGGACCCCTGGAAGAGCAGTTGGTGCTC TTAACTGCTG
  2769. Sstr3 + 5791 1.33e-17 GAAGGTCCAG GGGTGCAGAGCACAGGTGCGTTGCAGAGCCAGCCAGGGGTC CTCAGTTTAC
  2770. --------------------------------------------------------------------------------
  2771.  
  2772. --------------------------------------------------------------------------------
  2773. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 block diagrams
  2774. --------------------------------------------------------------------------------
  2775. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  2776. ------------- ---------------- -------------
  2777. Kiss1r 4e-22 3106_[+16]_3982
  2778. Htr6 1.5e-21 9570_[+16]_6206
  2779. Arl13b 1e-19 11160_[+16]_42545
  2780. Sstr3 1.3e-17 5790_[+16]_6525
  2781. --------------------------------------------------------------------------------
  2782.  
  2783. --------------------------------------------------------------------------------
  2784. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 in BLOCKS format
  2785. --------------------------------------------------------------------------------
  2786. BL MOTIF GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC width=41 seqs=4
  2787. Kiss1r ( 3107) AGGAGCTGAACCCAGGTCCTCTGAAAGAGCAGCTGGTGTTC 1
  2788. Htr6 ( 9571) GGGACCCGAACCCAGGTCCTCTGTAAGAGCAGGAAGTGCTC 1
  2789. Arl13b ( 11161) GGGAATTGAACTCAGGACCCCTGGAAGAGCAGTTGGTGCTC 1
  2790. Sstr3 ( 5791) GGGTGCAGAGCACAGGTGCGTTGCAGAGCCAGCCAGGGGTC 1
  2791. //
  2792.  
  2793. --------------------------------------------------------------------------------
  2794.  
  2795. --------------------------------------------------------------------------------
  2796. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 position-specific scoring matrix
  2797. --------------------------------------------------------------------------------
  2798. log-odds matrix: alength= 4 w= 41 n= 110060 bayes= 14.7479 E= 3.1e+000
  2799. -12 -865 172 -865
  2800. -865 -865 213 -865
  2801. -865 -865 213 -865
  2802. 146 -865 -865 -12
  2803. -12 14 113 -865
  2804. -865 172 -865 -12
  2805. -12 14 -865 87
  2806. -865 -865 213 -865
  2807. 187 -865 -865 -865
  2808. 146 -865 14 -865
  2809. -865 213 -865 -865
  2810. -12 113 -865 -12
  2811. -865 213 -865 -865
  2812. 187 -865 -865 -865
  2813. -865 -865 213 -865
  2814. -865 -865 213 -865
  2815. -12 -865 -865 146
  2816. -865 172 14 -865
  2817. -865 213 -865 -865
  2818. -865 14 14 87
  2819. -865 172 -865 -12
  2820. -865 -865 -865 187
  2821. -865 -865 213 -865
  2822. -12 14 14 -12
  2823. 187 -865 -865 -865
  2824. 146 -865 14 -865
  2825. -12 -865 172 -865
  2826. 146 -865 14 -865
  2827. -865 14 172 -865
  2828. -865 213 -865 -865
  2829. 187 -865 -865 -865
  2830. -865 -865 213 -865
  2831. -865 113 14 -12
  2832. -12 14 -865 87
  2833. 87 -865 113 -865
  2834. -865 -865 213 -865
  2835. -865 -865 14 146
  2836. -865 -865 213 -865
  2837. -865 113 14 -12
  2838. -865 -865 -865 187
  2839. -865 213 -865 -865
  2840. --------------------------------------------------------------------------------
  2841.  
  2842. --------------------------------------------------------------------------------
  2843. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 position-specific probability matrix
  2844. --------------------------------------------------------------------------------
  2845. letter-probability matrix: alength= 4 w= 41 nsites= 4 E= 3.1e+000
  2846. 0.250000 0.000000 0.750000 0.000000
  2847. 0.000000 0.000000 1.000000 0.000000
  2848. 0.000000 0.000000 1.000000 0.000000
  2849. 0.750000 0.000000 0.000000 0.250000
  2850. 0.250000 0.250000 0.500000 0.000000
  2851. 0.000000 0.750000 0.000000 0.250000
  2852. 0.250000 0.250000 0.000000 0.500000
  2853. 0.000000 0.000000 1.000000 0.000000
  2854. 1.000000 0.000000 0.000000 0.000000
  2855. 0.750000 0.000000 0.250000 0.000000
  2856. 0.000000 1.000000 0.000000 0.000000
  2857. 0.250000 0.500000 0.000000 0.250000
  2858. 0.000000 1.000000 0.000000 0.000000
  2859. 1.000000 0.000000 0.000000 0.000000
  2860. 0.000000 0.000000 1.000000 0.000000
  2861. 0.000000 0.000000 1.000000 0.000000
  2862. 0.250000 0.000000 0.000000 0.750000
  2863. 0.000000 0.750000 0.250000 0.000000
  2864. 0.000000 1.000000 0.000000 0.000000
  2865. 0.000000 0.250000 0.250000 0.500000
  2866. 0.000000 0.750000 0.000000 0.250000
  2867. 0.000000 0.000000 0.000000 1.000000
  2868. 0.000000 0.000000 1.000000 0.000000
  2869. 0.250000 0.250000 0.250000 0.250000
  2870. 1.000000 0.000000 0.000000 0.000000
  2871. 0.750000 0.000000 0.250000 0.000000
  2872. 0.250000 0.000000 0.750000 0.000000
  2873. 0.750000 0.000000 0.250000 0.000000
  2874. 0.000000 0.250000 0.750000 0.000000
  2875. 0.000000 1.000000 0.000000 0.000000
  2876. 1.000000 0.000000 0.000000 0.000000
  2877. 0.000000 0.000000 1.000000 0.000000
  2878. 0.000000 0.500000 0.250000 0.250000
  2879. 0.250000 0.250000 0.000000 0.500000
  2880. 0.500000 0.000000 0.500000 0.000000
  2881. 0.000000 0.000000 1.000000 0.000000
  2882. 0.000000 0.000000 0.250000 0.750000
  2883. 0.000000 0.000000 1.000000 0.000000
  2884. 0.000000 0.500000 0.250000 0.250000
  2885. 0.000000 0.000000 0.000000 1.000000
  2886. 0.000000 1.000000 0.000000 0.000000
  2887. --------------------------------------------------------------------------------
  2888.  
  2889. --------------------------------------------------------------------------------
  2890. Motif GGGAVCHGAACHCAGGTCCBCTGNAAGAGCAGBHRGTGBTC MEME-16 regular expression
  2891. --------------------------------------------------------------------------------
  2892. [GA]GG[AT][GAC][CT][TAC]GA[AG]C[CAT]CAGG[TA][CG]C[TCG][CT]TG[ACGT]A[AG][GA][AG][GC]CAG[CGT][TAC][AG]G[TG]G[CGT]TC
  2893. --------------------------------------------------------------------------------
  2894.  
  2895.  
  2896.  
  2897.  
  2898. Time 9912.11 secs.
  2899.  
  2900. ********************************************************************************
  2901.  
  2902.  
  2903. ********************************************************************************
  2904. MOTIF TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 width = 41 sites = 6 llr = 204 E-value = 1.5e-002
  2905. ********************************************************************************
  2906. --------------------------------------------------------------------------------
  2907. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 Description
  2908. --------------------------------------------------------------------------------
  2909. Simplified A :::22a::5::85::::::::::::2:7:22:::::::52:
  2910. pos.-specific C :3::3:27228::7a:3:a:2:::7::::32:5:3::35:5
  2911. probability G ::::::::23:23:::75:28:8a:582:3:7::3325:25
  2912. matrix T a7a85:83252:23:a:5:8:a2:3322a2735a3782:7:
  2913.  
  2914. bits 2.1 * * *
  2915. 1.9 * * * ** * * * * *
  2916. 1.7 * * * ** * * * * *
  2917. 1.5 * * * * ** * **** * * *
  2918. Relative 1.3 * ** ** ** *** ****** * * * *
  2919. Entropy 1.1 **** *** ** ************ * * *** ** * *
  2920. (49.1 bits) 0.9 **** *** ** ************ * * *** ** * *
  2921. 0.6 **** *** *** **************** **** ******
  2922. 0.4 ******** ******************** ***********
  2923. 0.2 *****************************************
  2924. 0.0 -----------------------------------------
  2925.  
  2926. Multilevel TTTTTATCATCAACCTGGCTGTGGCGGATCTGCTCTTGATC
  2927. consensus C C T G GT CT TT G TT GG CC G
  2928. sequence T
  2929.  
  2930. --------------------------------------------------------------------------------
  2931.  
  2932. --------------------------------------------------------------------------------
  2933. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 sites sorted by position p-value
  2934. --------------------------------------------------------------------------------
  2935. Sequence name Strand Start P-value Site
  2936. ------------- ------ ----- --------- -----------------------------------------
  2937. Mchr1 + 1791 1.25e-19 GTCCCTGACA TCTTCATCATCAACCTCTCTGTGGTGGATCTGCTTTTCCTG CTGGGCATGC
  2938. Npy2r + 7783 1.72e-17 GTAACCAACT TTTTTATTGCCAACCTGGCTGTGGCGGATCTTTTGGTGAAC ACCCTGTGCC
  2939. Sstr3 + 9069 9.67e-17 GTGACCAGTG TCTATATCCTCAACCTGGCTCTGGCTGATGAGCTCTTCATG CTAGGGCTAC
  2940. Mc4r + 689 1.67e-16 CCCATGTACT TTTTCATCTGTAGCCTGGCTGTGGCAGATATGCTGGTGAGC GTTTCGAATG
  2941. Htr6 + 5159 5.34e-15 GCTCTCTCGC TTTTAACCAGCATTCTCTCTGTGGTGGTTTTGTTTTGTCTC ACACCTGGAA
  2942. Arl13b + 33534 9.59e-15 CTATTGGTAG TTTTTATTATCGGTCTGTCGGTTGCTTGTGCTTTCTTGCTG GCAGCTTTTT
  2943. --------------------------------------------------------------------------------
  2944.  
  2945. --------------------------------------------------------------------------------
  2946. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 block diagrams
  2947. --------------------------------------------------------------------------------
  2948. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  2949. ------------- ---------------- -------------
  2950. Mchr1 1.2e-19 1790_[+17]_1635
  2951. Npy2r 1.7e-17 7782_[+17]_2784
  2952. Sstr3 9.7e-17 9068_[+17]_3247
  2953. Mc4r 1.7e-16 688_[+17]_2054
  2954. Htr6 5.3e-15 5158_[+17]_10618
  2955. Arl13b 9.6e-15 33533_[+17]_20172
  2956. --------------------------------------------------------------------------------
  2957.  
  2958. --------------------------------------------------------------------------------
  2959. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 in BLOCKS format
  2960. --------------------------------------------------------------------------------
  2961. BL MOTIF TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS width=41 seqs=6
  2962. Mchr1 ( 1791) TCTTCATCATCAACCTCTCTGTGGTGGATCTGCTTTTCCTG 1
  2963. Npy2r ( 7783) TTTTTATTGCCAACCTGGCTGTGGCGGATCTTTTGGTGAAC 1
  2964. Sstr3 ( 9069) TCTATATCCTCAACCTGGCTCTGGCTGATGAGCTCTTCATG 1
  2965. Mc4r ( 689) TTTTCATCTGTAGCCTGGCTGTGGCAGATATGCTGGTGAGC 1
  2966. Htr6 ( 5159) TTTTAACCAGCATTCTCTCTGTGGTGGTTTTGTTTTGTCTC 1
  2967. Arl13b ( 33534) TTTTTATTATCGGTCTGTCGGTTGCTTGTGCTTTCTTGCTG 1
  2968. //
  2969.  
  2970. --------------------------------------------------------------------------------
  2971.  
  2972. --------------------------------------------------------------------------------
  2973. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 position-specific scoring matrix
  2974. --------------------------------------------------------------------------------
  2975. log-odds matrix: alength= 4 w= 41 n= 110060 bayes= 13.9823 E= 1.5e-002
  2976. -923 -923 -923 187
  2977. -923 55 -923 129
  2978. -923 -923 -923 187
  2979. -71 -923 -923 161
  2980. -71 55 -923 88
  2981. 187 -923 -923 -923
  2982. -923 -45 -923 161
  2983. -923 155 -923 29
  2984. 88 -45 -45 -71
  2985. -923 -45 55 88
  2986. -923 187 -923 -71
  2987. 161 -923 -45 -923
  2988. 88 -923 55 -71
  2989. -923 155 -923 29
  2990. -923 213 -923 -923
  2991. -923 -923 -923 187
  2992. -923 55 155 -923
  2993. -923 -923 113 88
  2994. -923 213 -923 -923
  2995. -923 -923 -45 161
  2996. -923 -45 187 -923
  2997. -923 -923 -923 187
  2998. -923 -923 187 -71
  2999. -923 -923 213 -923
  3000. -923 155 -923 29
  3001. -71 -923 113 29
  3002. -923 -923 187 -71
  3003. 129 -923 -45 -71
  3004. -923 -923 -923 187
  3005. -71 55 55 -71
  3006. -71 -45 -923 129
  3007. -923 -923 155 29
  3008. -923 113 -923 88
  3009. -923 -923 -923 187
  3010. -923 55 55 29
  3011. -923 -923 55 129
  3012. -923 -923 -45 161
  3013. -923 55 113 -71
  3014. 88 113 -923 -923
  3015. -71 -923 -45 129
  3016. -923 113 113 -923
  3017. --------------------------------------------------------------------------------
  3018.  
  3019. --------------------------------------------------------------------------------
  3020. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 position-specific probability matrix
  3021. --------------------------------------------------------------------------------
  3022. letter-probability matrix: alength= 4 w= 41 nsites= 6 E= 1.5e-002
  3023. 0.000000 0.000000 0.000000 1.000000
  3024. 0.000000 0.333333 0.000000 0.666667
  3025. 0.000000 0.000000 0.000000 1.000000
  3026. 0.166667 0.000000 0.000000 0.833333
  3027. 0.166667 0.333333 0.000000 0.500000
  3028. 1.000000 0.000000 0.000000 0.000000
  3029. 0.000000 0.166667 0.000000 0.833333
  3030. 0.000000 0.666667 0.000000 0.333333
  3031. 0.500000 0.166667 0.166667 0.166667
  3032. 0.000000 0.166667 0.333333 0.500000
  3033. 0.000000 0.833333 0.000000 0.166667
  3034. 0.833333 0.000000 0.166667 0.000000
  3035. 0.500000 0.000000 0.333333 0.166667
  3036. 0.000000 0.666667 0.000000 0.333333
  3037. 0.000000 1.000000 0.000000 0.000000
  3038. 0.000000 0.000000 0.000000 1.000000
  3039. 0.000000 0.333333 0.666667 0.000000
  3040. 0.000000 0.000000 0.500000 0.500000
  3041. 0.000000 1.000000 0.000000 0.000000
  3042. 0.000000 0.000000 0.166667 0.833333
  3043. 0.000000 0.166667 0.833333 0.000000
  3044. 0.000000 0.000000 0.000000 1.000000
  3045. 0.000000 0.000000 0.833333 0.166667
  3046. 0.000000 0.000000 1.000000 0.000000
  3047. 0.000000 0.666667 0.000000 0.333333
  3048. 0.166667 0.000000 0.500000 0.333333
  3049. 0.000000 0.000000 0.833333 0.166667
  3050. 0.666667 0.000000 0.166667 0.166667
  3051. 0.000000 0.000000 0.000000 1.000000
  3052. 0.166667 0.333333 0.333333 0.166667
  3053. 0.166667 0.166667 0.000000 0.666667
  3054. 0.000000 0.000000 0.666667 0.333333
  3055. 0.000000 0.500000 0.000000 0.500000
  3056. 0.000000 0.000000 0.000000 1.000000
  3057. 0.000000 0.333333 0.333333 0.333333
  3058. 0.000000 0.000000 0.333333 0.666667
  3059. 0.000000 0.000000 0.166667 0.833333
  3060. 0.000000 0.333333 0.500000 0.166667
  3061. 0.500000 0.500000 0.000000 0.000000
  3062. 0.166667 0.000000 0.166667 0.666667
  3063. 0.000000 0.500000 0.500000 0.000000
  3064. --------------------------------------------------------------------------------
  3065.  
  3066. --------------------------------------------------------------------------------
  3067. Motif TYTTYATYAKCARYCTSKCTGTGGYKGATNTKYTBKTSMTS MEME-17 regular expression
  3068. --------------------------------------------------------------------------------
  3069. T[TC]TT[TC]AT[CT]A[TG]CA[AG][CT]CT[GC][GT]CTGTGG[CT][GT]GAT[CG]T[GT][CT]T[CGT][TG]T[GC][AC]T[CG]
  3070. --------------------------------------------------------------------------------
  3071.  
  3072.  
  3073.  
  3074.  
  3075. Time 10505.98 secs.
  3076.  
  3077. ********************************************************************************
  3078.  
  3079.  
  3080. ********************************************************************************
  3081. MOTIF GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 width = 49 sites = 4 llr = 189 E-value = 1.9e-002
  3082. ********************************************************************************
  3083. --------------------------------------------------------------------------------
  3084. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 Description
  3085. --------------------------------------------------------------------------------
  3086. Simplified A ::::8::5::358:83:8::::::::::3:::533::83::88::::53
  3087. pos.-specific C :a:5::5::5:3::3:a:a::3a::5:8::88::33::5a5::3::a::
  3088. probability G a::5:a:5a3:33a:8:3::a8::a:::3:3:3538a::::338:3::8
  3089. matrix T ::a:3:5::38::::::::a:::a:5a35a:3333::33:5:::a8:5:
  3090.  
  3091. bits 2.1 ** * * * * * * * * * * *
  3092. 1.9 *** * * * * *** *** * * * * * *
  3093. 1.7 *** * * * * *** *** * * * * * *
  3094. 1.5 *** * * * * *** *** * * * * * *
  3095. Relative 1.3 *** * * * ** ******* ** *** ** * ** * *
  3096. Entropy 1.1 ********* * **************** *** *** ******** *
  3097. (68.3 bits) 0.9 ********* * **************** *** *** **********
  3098. 0.6 *********** **************** *** *** **********
  3099. 0.4 ********************************** **************
  3100. 0.2 ********************************** **************
  3101. 0.0 -------------------------------------------------
  3102.  
  3103. Multilevel GCTCAGCAGCTAAGAGCACTGGCTGCTCTTCCAGAGGACCCAAGTTCAG
  3104. consensus GT TG GACG CA G C T TA GTGACC TA TGGC G TA
  3105. sequence T G G TTG T
  3106. T
  3107. --------------------------------------------------------------------------------
  3108.  
  3109. --------------------------------------------------------------------------------
  3110. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 sites sorted by position p-value
  3111. --------------------------------------------------------------------------------
  3112. Sequence name Strand Start P-value Site
  3113. ------------- ------ ----- --------- -------------------------------------------------
  3114. Kiss1r + 5772 2.07e-24 TGAAGAGACA GCTGAGTGGCTAAGAACACTGCCTGCTCTTCCAGAGGACCCAAGTGCAG GTCTCAGCAT
  3115. Htr6 - 8997 1.72e-23 AGAGATGTCG GCTCAGCAGTTCAGAGCACTGGCTGCTCTTGCAGCCGAACTAAGTTCTG ATCCCAGAAC
  3116. Arl13b - 28748 1.34e-21 TGCTGAGATG GCTCAGCAGGTAAGAGCACTGGCTGTTCATCTGATGGTCCTGAGTTCAA ATCCCAGCAG
  3117. Npy2r + 407 1.70e-20 CTGTGCCTGC GCTGTGTGGCAGGGCGCGCTGGCTGTTTGTCCTTGGGATCCAGCTTCTG CGAGGAGTTC
  3118. --------------------------------------------------------------------------------
  3119.  
  3120. --------------------------------------------------------------------------------
  3121. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 block diagrams
  3122. --------------------------------------------------------------------------------
  3123. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  3124. ------------- ---------------- -------------
  3125. Kiss1r 2.1e-24 5771_[+18]_1309
  3126. Htr6 1.7e-23 8996_[-18]_6772
  3127. Arl13b 1.3e-21 28747_[-18]_24950
  3128. Npy2r 1.7e-20 406_[+18]_10152
  3129. --------------------------------------------------------------------------------
  3130.  
  3131. --------------------------------------------------------------------------------
  3132. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 in BLOCKS format
  3133. --------------------------------------------------------------------------------
  3134. BL MOTIF GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG width=49 seqs=4
  3135. Kiss1r ( 5772) GCTGAGTGGCTAAGAACACTGCCTGCTCTTCCAGAGGACCCAAGTGCAG 1
  3136. Htr6 ( 8997) GCTCAGCAGTTCAGAGCACTGGCTGCTCTTGCAGCCGAACTAAGTTCTG 1
  3137. Arl13b ( 28748) GCTCAGCAGGTAAGAGCACTGGCTGTTCATCTGATGGTCCTGAGTTCAA 1
  3138. Npy2r ( 407) GCTGTGTGGCAGGGCGCGCTGGCTGTTTGTCCTTGGGATCCAGCTTCTG 1
  3139. //
  3140.  
  3141. --------------------------------------------------------------------------------
  3142.  
  3143. --------------------------------------------------------------------------------
  3144. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 position-specific scoring matrix
  3145. --------------------------------------------------------------------------------
  3146. log-odds matrix: alength= 4 w= 49 n= 109996 bayes= 14.0689 E= 1.9e-002
  3147. -865 -865 213 -865
  3148. -865 213 -865 -865
  3149. -865 -865 -865 187
  3150. -865 113 113 -865
  3151. 146 -865 -865 -12
  3152. -865 -865 213 -865
  3153. -865 113 -865 87
  3154. 87 -865 113 -865
  3155. -865 -865 213 -865
  3156. -865 113 14 -12
  3157. -12 -865 -865 146
  3158. 87 14 14 -865
  3159. 146 -865 14 -865
  3160. -865 -865 213 -865
  3161. 146 14 -865 -865
  3162. -12 -865 172 -865
  3163. -865 213 -865 -865
  3164. 146 -865 14 -865
  3165. -865 213 -865 -865
  3166. -865 -865 -865 187
  3167. -865 -865 213 -865
  3168. -865 14 172 -865
  3169. -865 213 -865 -865
  3170. -865 -865 -865 187
  3171. -865 -865 213 -865
  3172. -865 113 -865 87
  3173. -865 -865 -865 187
  3174. -865 172 -865 -12
  3175. -12 -865 14 87
  3176. -865 -865 -865 187
  3177. -865 172 14 -865
  3178. -865 172 -865 -12
  3179. 87 -865 14 -12
  3180. -12 -865 113 -12
  3181. -12 14 14 -12
  3182. -865 14 172 -865
  3183. -865 -865 213 -865
  3184. 146 -865 -865 -12
  3185. -12 113 -865 -12
  3186. -865 213 -865 -865
  3187. -865 113 -865 87
  3188. 146 -865 14 -865
  3189. 146 -865 14 -865
  3190. -865 14 172 -865
  3191. -865 -865 -865 187
  3192. -865 -865 14 146
  3193. -865 213 -865 -865
  3194. 87 -865 -865 87
  3195. -12 -865 172 -865
  3196. --------------------------------------------------------------------------------
  3197.  
  3198. --------------------------------------------------------------------------------
  3199. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 position-specific probability matrix
  3200. --------------------------------------------------------------------------------
  3201. letter-probability matrix: alength= 4 w= 49 nsites= 4 E= 1.9e-002
  3202. 0.000000 0.000000 1.000000 0.000000
  3203. 0.000000 1.000000 0.000000 0.000000
  3204. 0.000000 0.000000 0.000000 1.000000
  3205. 0.000000 0.500000 0.500000 0.000000
  3206. 0.750000 0.000000 0.000000 0.250000
  3207. 0.000000 0.000000 1.000000 0.000000
  3208. 0.000000 0.500000 0.000000 0.500000
  3209. 0.500000 0.000000 0.500000 0.000000
  3210. 0.000000 0.000000 1.000000 0.000000
  3211. 0.000000 0.500000 0.250000 0.250000
  3212. 0.250000 0.000000 0.000000 0.750000
  3213. 0.500000 0.250000 0.250000 0.000000
  3214. 0.750000 0.000000 0.250000 0.000000
  3215. 0.000000 0.000000 1.000000 0.000000
  3216. 0.750000 0.250000 0.000000 0.000000
  3217. 0.250000 0.000000 0.750000 0.000000
  3218. 0.000000 1.000000 0.000000 0.000000
  3219. 0.750000 0.000000 0.250000 0.000000
  3220. 0.000000 1.000000 0.000000 0.000000
  3221. 0.000000 0.000000 0.000000 1.000000
  3222. 0.000000 0.000000 1.000000 0.000000
  3223. 0.000000 0.250000 0.750000 0.000000
  3224. 0.000000 1.000000 0.000000 0.000000
  3225. 0.000000 0.000000 0.000000 1.000000
  3226. 0.000000 0.000000 1.000000 0.000000
  3227. 0.000000 0.500000 0.000000 0.500000
  3228. 0.000000 0.000000 0.000000 1.000000
  3229. 0.000000 0.750000 0.000000 0.250000
  3230. 0.250000 0.000000 0.250000 0.500000
  3231. 0.000000 0.000000 0.000000 1.000000
  3232. 0.000000 0.750000 0.250000 0.000000
  3233. 0.000000 0.750000 0.000000 0.250000
  3234. 0.500000 0.000000 0.250000 0.250000
  3235. 0.250000 0.000000 0.500000 0.250000
  3236. 0.250000 0.250000 0.250000 0.250000
  3237. 0.000000 0.250000 0.750000 0.000000
  3238. 0.000000 0.000000 1.000000 0.000000
  3239. 0.750000 0.000000 0.000000 0.250000
  3240. 0.250000 0.500000 0.000000 0.250000
  3241. 0.000000 1.000000 0.000000 0.000000
  3242. 0.000000 0.500000 0.000000 0.500000
  3243. 0.750000 0.000000 0.250000 0.000000
  3244. 0.750000 0.000000 0.250000 0.000000
  3245. 0.000000 0.250000 0.750000 0.000000
  3246. 0.000000 0.000000 0.000000 1.000000
  3247. 0.000000 0.000000 0.250000 0.750000
  3248. 0.000000 1.000000 0.000000 0.000000
  3249. 0.500000 0.000000 0.000000 0.500000
  3250. 0.250000 0.000000 0.750000 0.000000
  3251. --------------------------------------------------------------------------------
  3252.  
  3253. --------------------------------------------------------------------------------
  3254. Motif GCTSAGYRGBTVAGAGCACTGGCTGYTCDTCCDDNGGAHCYAAGTTCWG MEME-18 regular expression
  3255. --------------------------------------------------------------------------------
  3256. GCT[CG][AT]G[CT][AG]G[CGT][TA][ACG][AG]G[AC][GA]C[AG]CTG[GC]CTG[CT]T[CT][TAG]T[CG][CT][AGT][GAT][ACGT][GC]G[AT][CAT]C[CT][AG][AG][GC]T[TG]C[AT][GA]
  3257. --------------------------------------------------------------------------------
  3258.  
  3259.  
  3260.  
  3261.  
  3262. Time 11098.46 secs.
  3263.  
  3264. ********************************************************************************
  3265.  
  3266.  
  3267. ********************************************************************************
  3268. MOTIF MTGCCCCCCMCCCMCCACCA MEME-19 width = 20 sites = 6 llr = 128 E-value = 4.5e-001
  3269. ********************************************************************************
  3270. --------------------------------------------------------------------------------
  3271. Motif MTGCCCCCCMCCCMCCACCA MEME-19 Description
  3272. --------------------------------------------------------------------------------
  3273. Simplified A 52:22::2:52::5::7::8
  3274. pos.-specific C 5:278a88a58aa5aa2aa:
  3275. probability G ::7:::::::::::::2:::
  3276. matrix T :822::2::::::::::::2
  3277.  
  3278. bits 2.1 * * ** ** **
  3279. 1.9 * * ** ** **
  3280. 1.7 * * ** ** **
  3281. 1.5 ***** *** ** **
  3282. Relative 1.3 * ***** *** ** ***
  3283. Entropy 1.1 ** ************ ***
  3284. (30.7 bits) 0.9 **************** ***
  3285. 0.6 ********************
  3286. 0.4 ********************
  3287. 0.2 ********************
  3288. 0.0 --------------------
  3289.  
  3290. Multilevel ATGCCCCCCACCCACCACCA
  3291. consensus C C C
  3292. sequence
  3293.  
  3294. --------------------------------------------------------------------------------
  3295.  
  3296. --------------------------------------------------------------------------------
  3297. Motif MTGCCCCCCMCCCMCCACCA MEME-19 sites sorted by position p-value
  3298. --------------------------------------------------------------------------------
  3299. Sequence name Strand Start P-value Site
  3300. ------------- ------ ----- --------- --------------------
  3301. Htr6 - 14322 4.70e-12 CTCCGAGACA CTGCCCCCCACCCCCCGCCA GCCACACTAC
  3302. Arl13b + 8749 8.70e-12 CTCATCTCTT CTCCCCCCCACCCCCCACCA CTCCAAGCTT
  3303. Sstr3 + 3787 1.29e-10 CAGCACCAAG AAGTCCCCCCCCCACCACCA CCTTGGACCC
  3304. Npy2r - 1567 2.05e-10 TTAAATATTA CTGCCCCACCACCACCACCA CCATGCCACA
  3305. Mchr1 - 648 2.68e-10 TCCAGCCTTG ATTCCCCCCCCCCCCCCCCT GCAAAGCATA
  3306. Mc4r + 448 8.48e-10 CTGCAGGAAG ATGAACTCCACCCACCACCA TGGCATGTAT
  3307. --------------------------------------------------------------------------------
  3308.  
  3309. --------------------------------------------------------------------------------
  3310. Motif MTGCCCCCCMCCCMCCACCA MEME-19 block diagrams
  3311. --------------------------------------------------------------------------------
  3312. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  3313. ------------- ---------------- -------------
  3314. Htr6 4.7e-12 14321_[-19]_1476
  3315. Arl13b 8.7e-12 8748_[+19]_44978
  3316. Sstr3 1.3e-10 3786_[+19]_8550
  3317. Npy2r 2e-10 1566_[-19]_9021
  3318. Mchr1 2.7e-10 647_[-19]_2799
  3319. Mc4r 8.5e-10 447_[+19]_2316
  3320. --------------------------------------------------------------------------------
  3321.  
  3322. --------------------------------------------------------------------------------
  3323. Motif MTGCCCCCCMCCCMCCACCA MEME-19 in BLOCKS format
  3324. --------------------------------------------------------------------------------
  3325. BL MOTIF MTGCCCCCCMCCCMCCACCA width=20 seqs=6
  3326. Htr6 ( 14322) CTGCCCCCCACCCCCCGCCA 1
  3327. Arl13b ( 8749) CTCCCCCCCACCCCCCACCA 1
  3328. Sstr3 ( 3787) AAGTCCCCCCCCCACCACCA 1
  3329. Npy2r ( 1567) CTGCCCCACCACCACCACCA 1
  3330. Mchr1 ( 648) ATTCCCCCCCCCCCCCCCCT 1
  3331. Mc4r ( 448) ATGAACTCCACCCACCACCA 1
  3332. //
  3333.  
  3334. --------------------------------------------------------------------------------
  3335.  
  3336. --------------------------------------------------------------------------------
  3337. Motif MTGCCCCCCMCCCMCCACCA MEME-19 position-specific scoring matrix
  3338. --------------------------------------------------------------------------------
  3339. log-odds matrix: alength= 4 w= 20 n= 110228 bayes= 13.9845 E= 4.5e-001
  3340. 88 113 -923 -923
  3341. -71 -923 -923 161
  3342. -923 -45 155 -71
  3343. -71 155 -923 -71
  3344. -71 187 -923 -923
  3345. -923 213 -923 -923
  3346. -923 187 -923 -71
  3347. -71 187 -923 -923
  3348. -923 213 -923 -923
  3349. 88 113 -923 -923
  3350. -71 187 -923 -923
  3351. -923 213 -923 -923
  3352. -923 213 -923 -923
  3353. 88 113 -923 -923
  3354. -923 213 -923 -923
  3355. -923 213 -923 -923
  3356. 129 -45 -45 -923
  3357. -923 213 -923 -923
  3358. -923 213 -923 -923
  3359. 161 -923 -923 -71
  3360. --------------------------------------------------------------------------------
  3361.  
  3362. --------------------------------------------------------------------------------
  3363. Motif MTGCCCCCCMCCCMCCACCA MEME-19 position-specific probability matrix
  3364. --------------------------------------------------------------------------------
  3365. letter-probability matrix: alength= 4 w= 20 nsites= 6 E= 4.5e-001
  3366. 0.500000 0.500000 0.000000 0.000000
  3367. 0.166667 0.000000 0.000000 0.833333
  3368. 0.000000 0.166667 0.666667 0.166667
  3369. 0.166667 0.666667 0.000000 0.166667
  3370. 0.166667 0.833333 0.000000 0.000000
  3371. 0.000000 1.000000 0.000000 0.000000
  3372. 0.000000 0.833333 0.000000 0.166667
  3373. 0.166667 0.833333 0.000000 0.000000
  3374. 0.000000 1.000000 0.000000 0.000000
  3375. 0.500000 0.500000 0.000000 0.000000
  3376. 0.166667 0.833333 0.000000 0.000000
  3377. 0.000000 1.000000 0.000000 0.000000
  3378. 0.000000 1.000000 0.000000 0.000000
  3379. 0.500000 0.500000 0.000000 0.000000
  3380. 0.000000 1.000000 0.000000 0.000000
  3381. 0.000000 1.000000 0.000000 0.000000
  3382. 0.666667 0.166667 0.166667 0.000000
  3383. 0.000000 1.000000 0.000000 0.000000
  3384. 0.000000 1.000000 0.000000 0.000000
  3385. 0.833333 0.000000 0.000000 0.166667
  3386. --------------------------------------------------------------------------------
  3387.  
  3388. --------------------------------------------------------------------------------
  3389. Motif MTGCCCCCCMCCCMCCACCA MEME-19 regular expression
  3390. --------------------------------------------------------------------------------
  3391. [AC]TGCCCCCC[AC]CCC[AC]CCACCA
  3392. --------------------------------------------------------------------------------
  3393.  
  3394.  
  3395.  
  3396.  
  3397. Time 11688.98 secs.
  3398.  
  3399. ********************************************************************************
  3400.  
  3401.  
  3402. ********************************************************************************
  3403. MOTIF AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 width = 41 sites = 7 llr = 206 E-value = 1.1e+001
  3404. ********************************************************************************
  3405. --------------------------------------------------------------------------------
  3406. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 Description
  3407. --------------------------------------------------------------------------------
  3408. Simplified A 971:::6::3:113:4a:4:73166:31:19:1616:1:64
  3409. pos.-specific C :::3374194:1::9::9::::33::3:791:1491:99::
  3410. probability G 139643:31:366111:1:63431:a:11::a7::36:1:6
  3411. matrix T :::13::6:37136:4::64:33:4:471:::::::4::4:
  3412.  
  3413. bits 2.1 * *
  3414. 1.9 * * *
  3415. 1.7 * * *
  3416. 1.5 * * * ** * * * * **
  3417. Relative 1.3 * * * * * ** * *** * **
  3418. Entropy 1.1 *** ** * * * ** ** * *** ** *** *
  3419. (42.4 bits) 0.9 *** ** * * * ***** ** ******** *****
  3420. 0.6 **** **** * *** ***** *** **************
  3421. 0.4 ********************** ******************
  3422. 0.2 ********************** ******************
  3423. 0.0 -----------------------------------------
  3424.  
  3425. Multilevel AAGGGCATCCTGGTCAACTGAGCAAGTTCCAGGACAGCCAG
  3426. consensus G CCGCG AG TA T ATGAGCT A C GT TA
  3427. sequence T T TT C
  3428.  
  3429. --------------------------------------------------------------------------------
  3430.  
  3431. --------------------------------------------------------------------------------
  3432. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 sites sorted by position p-value
  3433. --------------------------------------------------------------------------------
  3434. Sequence name Strand Start P-value Site
  3435. ------------- ------ ----- --------- -----------------------------------------
  3436. Arl13b + 49729 5.52e-20 TTCTGAATTC AAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAG CAGCCAGGGC
  3437. Htr6 - 12521 3.57e-18 CTGTAAATTC AAGGCCAGCTTGATCTACAGAACAAGTTCCAGGACAGCCAA AGCGATACAG
  3438. Kiss1r + 5537 7.84e-17 ACTGGAGTCC AAGGTCATCCTCGGCTACATAAAATGTTCCAGGCCAGCCTG GCTGACTGCT
  3439. Npy2r + 5456 7.85e-14 CTGCAAGACT AGGTGCATCCTTGTCAACTGAGGCTGCACAAGGCAGTCCAG TTATGGGAAA
  3440. Sstr3 - 5849 9.17e-13 TGGCTTCCTT AAAGGCCTCTGGTTGGAGTTGTCAAGAGTCAGGACATCCAG GGACAATGTA
  3441. Mc4r - 936 1.49e-12 GACACAGTGC AAGCTGCCCAGATACAACTTATGATGATCCCGACCCGCCTA ACCGTCATGA
  3442. Mchr1 - 2366 6.22e-12 TGTGAGGGTC GGGCGGCTGATGGACAACTGGGTCAGCTGCAGCACGTAGTA GGGCGCCCAG
  3443. --------------------------------------------------------------------------------
  3444.  
  3445. --------------------------------------------------------------------------------
  3446. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 block diagrams
  3447. --------------------------------------------------------------------------------
  3448. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  3449. ------------- ---------------- -------------
  3450. Arl13b 5.5e-20 49728_[+20]_3977
  3451. Htr6 3.6e-18 12520_[-20]_3256
  3452. Kiss1r 7.8e-17 5536_[+20]_1552
  3453. Npy2r 7.9e-14 5455_[+20]_5111
  3454. Sstr3 9.2e-13 5848_[-20]_6467
  3455. Mc4r 1.5e-12 935_[-20]_1807
  3456. Mchr1 6.2e-12 2365_[-20]_1060
  3457. --------------------------------------------------------------------------------
  3458.  
  3459. --------------------------------------------------------------------------------
  3460. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 in BLOCKS format
  3461. --------------------------------------------------------------------------------
  3462. BL MOTIF AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR width=41 seqs=7
  3463. Arl13b ( 49729) AAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAG 1
  3464. Htr6 ( 12521) AAGGCCAGCTTGATCTACAGAACAAGTTCCAGGACAGCCAA 1
  3465. Kiss1r ( 5537) AAGGTCATCCTCGGCTACATAAAATGTTCCAGGCCAGCCTG 1
  3466. Npy2r ( 5456) AGGTGCATCCTTGTCAACTGAGGCTGCACAAGGCAGTCCAG 1
  3467. Sstr3 ( 5849) AAAGGCCTCTGGTTGGAGTTGTCAAGAGTCAGGACATCCAG 1
  3468. Mc4r ( 936) AAGCTGCCCAGATACAACTTATGATGATCCCGACCCGCCTA 1
  3469. Mchr1 ( 2366) GGGCGGCTGATGGACAACTGGGTCAGCTGCAGCACGTAGTA 1
  3470. //
  3471.  
  3472. --------------------------------------------------------------------------------
  3473.  
  3474. --------------------------------------------------------------------------------
  3475. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 position-specific scoring matrix
  3476. --------------------------------------------------------------------------------
  3477. log-odds matrix: alength= 4 w= 41 n= 110060 bayes= 14.5462 E= 1.1e+001
  3478. 165 -945 -67 -945
  3479. 139 -945 33 -945
  3480. -93 -945 191 -945
  3481. -945 33 133 -93
  3482. -945 33 91 7
  3483. -945 165 33 -945
  3484. 107 91 -945 -945
  3485. -945 -67 33 107
  3486. -945 191 -67 -945
  3487. 7 91 -945 7
  3488. -945 -945 33 139
  3489. -93 -67 133 -93
  3490. -93 -945 133 7
  3491. 7 -945 -67 107
  3492. -945 191 -67 -945
  3493. 65 -945 -67 65
  3494. 187 -945 -945 -945
  3495. -945 191 -67 -945
  3496. 65 -945 -945 107
  3497. -945 -945 133 65
  3498. 139 -945 33 -945
  3499. 7 -945 91 7
  3500. -93 33 33 7
  3501. 107 33 -67 -945
  3502. 107 -945 -945 65
  3503. -945 -945 213 -945
  3504. 7 33 -945 65
  3505. -93 -945 -67 139
  3506. -945 165 -67 -93
  3507. -93 191 -945 -945
  3508. 165 -67 -945 -945
  3509. -945 -945 213 -945
  3510. -93 -67 165 -945
  3511. 107 91 -945 -945
  3512. -93 191 -945 -945
  3513. 107 -67 33 -945
  3514. -945 -945 133 65
  3515. -93 191 -945 -945
  3516. -945 191 -67 -945
  3517. 107 -945 -945 65
  3518. 65 -945 133 -945
  3519. --------------------------------------------------------------------------------
  3520.  
  3521. --------------------------------------------------------------------------------
  3522. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 position-specific probability matrix
  3523. --------------------------------------------------------------------------------
  3524. letter-probability matrix: alength= 4 w= 41 nsites= 7 E= 1.1e+001
  3525. 0.857143 0.000000 0.142857 0.000000
  3526. 0.714286 0.000000 0.285714 0.000000
  3527. 0.142857 0.000000 0.857143 0.000000
  3528. 0.000000 0.285714 0.571429 0.142857
  3529. 0.000000 0.285714 0.428571 0.285714
  3530. 0.000000 0.714286 0.285714 0.000000
  3531. 0.571429 0.428571 0.000000 0.000000
  3532. 0.000000 0.142857 0.285714 0.571429
  3533. 0.000000 0.857143 0.142857 0.000000
  3534. 0.285714 0.428571 0.000000 0.285714
  3535. 0.000000 0.000000 0.285714 0.714286
  3536. 0.142857 0.142857 0.571429 0.142857
  3537. 0.142857 0.000000 0.571429 0.285714
  3538. 0.285714 0.000000 0.142857 0.571429
  3539. 0.000000 0.857143 0.142857 0.000000
  3540. 0.428571 0.000000 0.142857 0.428571
  3541. 1.000000 0.000000 0.000000 0.000000
  3542. 0.000000 0.857143 0.142857 0.000000
  3543. 0.428571 0.000000 0.000000 0.571429
  3544. 0.000000 0.000000 0.571429 0.428571
  3545. 0.714286 0.000000 0.285714 0.000000
  3546. 0.285714 0.000000 0.428571 0.285714
  3547. 0.142857 0.285714 0.285714 0.285714
  3548. 0.571429 0.285714 0.142857 0.000000
  3549. 0.571429 0.000000 0.000000 0.428571
  3550. 0.000000 0.000000 1.000000 0.000000
  3551. 0.285714 0.285714 0.000000 0.428571
  3552. 0.142857 0.000000 0.142857 0.714286
  3553. 0.000000 0.714286 0.142857 0.142857
  3554. 0.142857 0.857143 0.000000 0.000000
  3555. 0.857143 0.142857 0.000000 0.000000
  3556. 0.000000 0.000000 1.000000 0.000000
  3557. 0.142857 0.142857 0.714286 0.000000
  3558. 0.571429 0.428571 0.000000 0.000000
  3559. 0.142857 0.857143 0.000000 0.000000
  3560. 0.571429 0.142857 0.285714 0.000000
  3561. 0.000000 0.000000 0.571429 0.428571
  3562. 0.142857 0.857143 0.000000 0.000000
  3563. 0.000000 0.857143 0.142857 0.000000
  3564. 0.571429 0.000000 0.000000 0.428571
  3565. 0.428571 0.000000 0.571429 0.000000
  3566. --------------------------------------------------------------------------------
  3567.  
  3568. --------------------------------------------------------------------------------
  3569. Motif AAGSBCMKCHTGKWCWACWKADNMWGHTCCAGGMCRKCCWR MEME-20 regular expression
  3570. --------------------------------------------------------------------------------
  3571. A[AG]G[GC][GCT][CG][AC][TG]C[CAT][TG]G[GT][TA]C[AT]AC[TA][GT][AG][GAT][CGT][AC][AT]G[TAC]TCCAGG[AC]C[AG][GT]CC[AT][GA]
  3572. --------------------------------------------------------------------------------
  3573.  
  3574.  
  3575.  
  3576.  
  3577. Time 12273.60 secs.
  3578.  
  3579. ********************************************************************************
  3580.  
  3581.  
  3582. ********************************************************************************
  3583. MOTIF GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 width = 29 sites = 7 llr = 165 E-value = 5.8e+001
  3584. ********************************************************************************
  3585. --------------------------------------------------------------------------------
  3586. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 Description
  3587. --------------------------------------------------------------------------------
  3588. Simplified A :171:733::71:7363919:9:1363::
  3589. pos.-specific C ::::1114::1::::13::::::1:3:::
  3590. probability G 96199:637a:9a1334191a1967:79a
  3591. matrix T 131::1::3:1::14:::::::11:1:1:
  3592.  
  3593. bits 2.1 * * * *
  3594. 1.9 * * * *
  3595. 1.7 * * * *
  3596. 1.5 * ** * ** * * * **
  3597. Relative 1.3 * ** ** ** ****** * ***
  3598. Entropy 1.1 * ** ** ** ****** * ***
  3599. (34.1 bits) 0.9 * **** ****** ****** * ***
  3600. 0.6 ******* ****** * ****** *****
  3601. 0.4 *****************************
  3602. 0.2 *****************************
  3603. 0.0 -----------------------------
  3604.  
  3605. Multilevel GGAGGAGCGGAGGATAGAGAGAGGGAGGG
  3606. consensus T AAT AGA ACA
  3607. sequence G G C
  3608.  
  3609. --------------------------------------------------------------------------------
  3610.  
  3611. --------------------------------------------------------------------------------
  3612. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 sites sorted by position p-value
  3613. --------------------------------------------------------------------------------
  3614. Sequence name Strand Start P-value Site
  3615. ------------- ------ ----- --------- -----------------------------
  3616. Sstr3 + 9937 2.03e-15 GAAGGGAAGA GGAGGAGCGGAGGATGCAGAGAGGGCAGG AGATGAACGG
  3617. Htr6 - 10702 1.05e-13 CAGAGGGAGG GAAGGAGGGGAGGAGGAAGGGAGGGAGGG AGGGGAAGAG
  3618. Arl13b - 36342 7.95e-13 AATGAATGGA GGAAGAGAGGAAGAAAGAGAGAGTGAGGG GATTTTTGGA
  3619. Kiss1r - 5317 3.75e-12 AAACACATAA GTGGGAAAGGAGGAAAAAGAGAGAGTGGG CATTTAGTTT
  3620. Npy2r - 5697 8.76e-11 TGGGGAATCC TGAGGAAGGGTGGGGAGGGAGAGGACAGG GAACCAGGGG
  3621. Mchr1 - 1613 1.83e-10 TGTGCGAGGA GGTGGCCCTGAGGATAGAAAGAGCAAGTG TGACCCGCCT
  3622. Mc4r - 482 5.69e-10 CGTGCAGCCC GTAGCTGCTGCGGTTCCAGAGGTGGAGGG AAGTATACAT
  3623. --------------------------------------------------------------------------------
  3624.  
  3625. --------------------------------------------------------------------------------
  3626. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 block diagrams
  3627. --------------------------------------------------------------------------------
  3628. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  3629. ------------- ---------------- -------------
  3630. Sstr3 2e-15 9936_[+21]_2391
  3631. Htr6 1.1e-13 10701_[-21]_5087
  3632. Arl13b 7.9e-13 36341_[-21]_17376
  3633. Kiss1r 3.8e-12 5316_[-21]_1784
  3634. Npy2r 8.8e-11 5696_[-21]_4882
  3635. Mchr1 1.8e-10 1612_[-21]_1825
  3636. Mc4r 5.7e-10 481_[-21]_2273
  3637. --------------------------------------------------------------------------------
  3638.  
  3639. --------------------------------------------------------------------------------
  3640. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 in BLOCKS format
  3641. --------------------------------------------------------------------------------
  3642. BL MOTIF GKAGGARVGGAGGADRVAGAGAGGGMGGG width=29 seqs=7
  3643. Sstr3 ( 9937) GGAGGAGCGGAGGATGCAGAGAGGGCAGG 1
  3644. Htr6 ( 10702) GAAGGAGGGGAGGAGGAAGGGAGGGAGGG 1
  3645. Arl13b ( 36342) GGAAGAGAGGAAGAAAGAGAGAGTGAGGG 1
  3646. Kiss1r ( 5317) GTGGGAAAGGAGGAAAAAGAGAGAGTGGG 1
  3647. Npy2r ( 5697) TGAGGAAGGGTGGGGAGGGAGAGGACAGG 1
  3648. Mchr1 ( 1613) GGTGGCCCTGAGGATAGAAAGAGCAAGTG 1
  3649. Mc4r ( 482) GTAGCTGCTGCGGTTCCAGAGGTGGAGGG 1
  3650. //
  3651.  
  3652. --------------------------------------------------------------------------------
  3653.  
  3654. --------------------------------------------------------------------------------
  3655. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 position-specific scoring matrix
  3656. --------------------------------------------------------------------------------
  3657. log-odds matrix: alength= 4 w= 29 n= 110156 bayes= 13.9417 E= 5.8e+001
  3658. -945 -945 191 -93
  3659. -93 -945 133 7
  3660. 139 -945 -67 -93
  3661. -93 -945 191 -945
  3662. -945 -67 191 -945
  3663. 139 -67 -945 -93
  3664. 7 -67 133 -945
  3665. 7 91 33 -945
  3666. -945 -945 165 7
  3667. -945 -945 213 -945
  3668. 139 -67 -945 -93
  3669. -93 -945 191 -945
  3670. -945 -945 213 -945
  3671. 139 -945 -67 -93
  3672. 7 -945 33 65
  3673. 107 -67 33 -945
  3674. 7 33 91 -945
  3675. 165 -945 -67 -945
  3676. -93 -945 191 -945
  3677. 165 -945 -67 -945
  3678. -945 -945 213 -945
  3679. 165 -945 -67 -945
  3680. -945 -945 191 -93
  3681. -93 -67 133 -93
  3682. 7 -945 165 -945
  3683. 107 33 -945 -93
  3684. 7 -945 165 -945
  3685. -945 -945 191 -93
  3686. -945 -945 213 -945
  3687. --------------------------------------------------------------------------------
  3688.  
  3689. --------------------------------------------------------------------------------
  3690. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 position-specific probability matrix
  3691. --------------------------------------------------------------------------------
  3692. letter-probability matrix: alength= 4 w= 29 nsites= 7 E= 5.8e+001
  3693. 0.000000 0.000000 0.857143 0.142857
  3694. 0.142857 0.000000 0.571429 0.285714
  3695. 0.714286 0.000000 0.142857 0.142857
  3696. 0.142857 0.000000 0.857143 0.000000
  3697. 0.000000 0.142857 0.857143 0.000000
  3698. 0.714286 0.142857 0.000000 0.142857
  3699. 0.285714 0.142857 0.571429 0.000000
  3700. 0.285714 0.428571 0.285714 0.000000
  3701. 0.000000 0.000000 0.714286 0.285714
  3702. 0.000000 0.000000 1.000000 0.000000
  3703. 0.714286 0.142857 0.000000 0.142857
  3704. 0.142857 0.000000 0.857143 0.000000
  3705. 0.000000 0.000000 1.000000 0.000000
  3706. 0.714286 0.000000 0.142857 0.142857
  3707. 0.285714 0.000000 0.285714 0.428571
  3708. 0.571429 0.142857 0.285714 0.000000
  3709. 0.285714 0.285714 0.428571 0.000000
  3710. 0.857143 0.000000 0.142857 0.000000
  3711. 0.142857 0.000000 0.857143 0.000000
  3712. 0.857143 0.000000 0.142857 0.000000
  3713. 0.000000 0.000000 1.000000 0.000000
  3714. 0.857143 0.000000 0.142857 0.000000
  3715. 0.000000 0.000000 0.857143 0.142857
  3716. 0.142857 0.142857 0.571429 0.142857
  3717. 0.285714 0.000000 0.714286 0.000000
  3718. 0.571429 0.285714 0.000000 0.142857
  3719. 0.285714 0.000000 0.714286 0.000000
  3720. 0.000000 0.000000 0.857143 0.142857
  3721. 0.000000 0.000000 1.000000 0.000000
  3722. --------------------------------------------------------------------------------
  3723.  
  3724. --------------------------------------------------------------------------------
  3725. Motif GKAGGARVGGAGGADRVAGAGAGGGMGGG MEME-21 regular expression
  3726. --------------------------------------------------------------------------------
  3727. G[GT]AGGA[GA][CAG][GT]GAGGA[TAG][AG][GAC]AGAGAGG[GA][AC][GA]GG
  3728. --------------------------------------------------------------------------------
  3729.  
  3730.  
  3731.  
  3732.  
  3733. Time 12862.95 secs.
  3734.  
  3735. ********************************************************************************
  3736.  
  3737.  
  3738. ********************************************************************************
  3739. MOTIF KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 width = 48 sites = 6 llr = 207 E-value = 3.1e-001
  3740. ********************************************************************************
  3741. --------------------------------------------------------------------------------
  3742. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 Description
  3743. --------------------------------------------------------------------------------
  3744. Simplified A :23::2:237:2::88:7::2::3:28a::::3::3:::a:2:2::22
  3745. pos.-specific C 235:2258::5:37:28:58:37337::7aa55:55:7::32573:77
  3746. probability G 53::853:::337::::2523323:22::::2::22:2:::73:222:
  3747. matrix T 322a:22:7325:32:22::532:7:::3::32a3:a2a:7:2258:2
  3748.  
  3749. bits 2.1 **
  3750. 1.9 * * ** * * **
  3751. 1.7 * * ** * * **
  3752. 1.5 ** * * * * ** * * **
  3753. Relative 1.3 ** * * *** * ** ** * * ** *
  3754. Entropy 1.1 ** * ***** ** * ***** * * *** *
  3755. (49.7 bits) 0.9 ** *** ***** ** * ******* * ****** * ***
  3756. 0.6 * *** ***** ******** * ************************
  3757. 0.4 * *** ******************************************
  3758. 0.2 ************************************************
  3759. 0.0 ------------------------------------------------
  3760.  
  3761. Multilevel GCCTGGCCTACTGCAACACCTCCATCAACCCCCTCCTCTATGCCTTCC
  3762. consensus TGA G ATGGCT G GG CC T TA TA C G C
  3763. sequence T G
  3764.  
  3765. --------------------------------------------------------------------------------
  3766.  
  3767. --------------------------------------------------------------------------------
  3768. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 sites sorted by position p-value
  3769. --------------------------------------------------------------------------------
  3770. Sequence name Strand Start P-value Site
  3771. ------------- ------ ----- --------- ------------------------------------------------
  3772. Sstr3 + 9750 3.36e-20 CTGGTGGTGG CGCTGCCCTACGCCAACAGCTGCGCAAACCCCATCCTCTACGGCTTCC TCTCCTACCG
  3773. Kiss1r + 4783 1.20e-17 TGGGCTCACT GCATGTCCTACAGCAACTCGGCGCTCAATCCGCTGCTCTATGCCTTCC TGGGTTCACA
  3774. Htr6 + 13705 9.03e-17 GTCCTCACAT GGCTGGGATACTGTAATAGCACCATGAACCCTATCATCTATCCCCTCT TCATGCGGGA
  3775. Mc4r + 1313 1.26e-16 TTGTATCTCA TACTGATCATGTGTAACGCCGTCATCGACCCTCTCATTTATGCCCTCC GGAGTCAAGA
  3776. Mchr1 + 2445 3.77e-15 GCGGCTATCA GCTTGGGCTATGCCAACAGCTGCCTCAATCCCTTTGTGTACATAGTAC TCTGTGAGAC
  3777. Npy2r + 8458 8.37e-15 GTGTTCCACA TTATCGCCATGTGCTCCACCTTTGCCAACCCCCTTCTCTATGGTTGGA TGAATAGCAA
  3778. --------------------------------------------------------------------------------
  3779.  
  3780. --------------------------------------------------------------------------------
  3781. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 block diagrams
  3782. --------------------------------------------------------------------------------
  3783. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  3784. ------------- ---------------- -------------
  3785. Sstr3 3.4e-20 9749_[+22]_2559
  3786. Kiss1r 1.2e-17 4782_[+22]_2299
  3787. Htr6 9e-17 13704_[+22]_2065
  3788. Mc4r 1.3e-16 1312_[+22]_1423
  3789. Mchr1 3.8e-15 2444_[+22]_974
  3790. Npy2r 8.4e-15 8457_[+22]_2102
  3791. --------------------------------------------------------------------------------
  3792.  
  3793. --------------------------------------------------------------------------------
  3794. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 in BLOCKS format
  3795. --------------------------------------------------------------------------------
  3796. BL MOTIF KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC width=48 seqs=6
  3797. Sstr3 ( 9750) CGCTGCCCTACGCCAACAGCTGCGCAAACCCCATCCTCTACGGCTTCC 1
  3798. Kiss1r ( 4783) GCATGTCCTACAGCAACTCGGCGCTCAATCCGCTGCTCTATGCCTTCC 1
  3799. Htr6 ( 13705) GGCTGGGATACTGTAATAGCACCATGAACCCTATCATCTATCCCCTCT 1
  3800. Mc4r ( 1313) TACTGATCATGTGTAACGCCGTCATCGACCCTCTCATTTATGCCCTCC 1
  3801. Mchr1 ( 2445) GCTTGGGCTATGCCAACAGCTGCCTCAATCCCTTTGTGTACATAGTAC 1
  3802. Npy2r ( 8458) TTATCGCCATGTGCTCCACCTTTGCCAACCCCCTTCTCTATGGTTGGA 1
  3803. //
  3804.  
  3805. --------------------------------------------------------------------------------
  3806.  
  3807. --------------------------------------------------------------------------------
  3808. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 position-specific scoring matrix
  3809. --------------------------------------------------------------------------------
  3810. log-odds matrix: alength= 4 w= 48 n= 110004 bayes= 13.9816 E= 3.1e-001
  3811. -923 -45 113 29
  3812. -71 55 55 -71
  3813. 29 113 -923 -71
  3814. -923 -923 -923 187
  3815. -923 -45 187 -923
  3816. -71 -45 113 -71
  3817. -923 113 55 -71
  3818. -71 187 -923 -923
  3819. 29 -923 -923 129
  3820. 129 -923 -923 29
  3821. -923 113 55 -71
  3822. -71 -923 55 88
  3823. -923 55 155 -923
  3824. -923 155 -923 29
  3825. 161 -923 -923 -71
  3826. 161 -45 -923 -923
  3827. -923 187 -923 -71
  3828. 129 -923 -45 -71
  3829. -923 113 113 -923
  3830. -923 187 -45 -923
  3831. -71 -923 55 88
  3832. -923 55 55 29
  3833. -923 155 -45 -71
  3834. 29 55 55 -923
  3835. -923 55 -923 129
  3836. -71 155 -45 -923
  3837. 161 -923 -45 -923
  3838. 187 -923 -923 -923
  3839. -923 155 -923 29
  3840. -923 213 -923 -923
  3841. -923 213 -923 -923
  3842. -923 113 -45 29
  3843. 29 113 -923 -71
  3844. -923 -923 -923 187
  3845. -923 113 -45 29
  3846. 29 113 -45 -923
  3847. -923 -923 -923 187
  3848. -923 155 -45 -71
  3849. -923 -923 -923 187
  3850. 187 -923 -923 -923
  3851. -923 55 -923 129
  3852. -71 -45 155 -923
  3853. -923 113 55 -71
  3854. -71 155 -923 -71
  3855. -923 55 -45 88
  3856. -923 -923 -45 161
  3857. -71 155 -45 -923
  3858. -71 155 -923 -71
  3859. --------------------------------------------------------------------------------
  3860.  
  3861. --------------------------------------------------------------------------------
  3862. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 position-specific probability matrix
  3863. --------------------------------------------------------------------------------
  3864. letter-probability matrix: alength= 4 w= 48 nsites= 6 E= 3.1e-001
  3865. 0.000000 0.166667 0.500000 0.333333
  3866. 0.166667 0.333333 0.333333 0.166667
  3867. 0.333333 0.500000 0.000000 0.166667
  3868. 0.000000 0.000000 0.000000 1.000000
  3869. 0.000000 0.166667 0.833333 0.000000
  3870. 0.166667 0.166667 0.500000 0.166667
  3871. 0.000000 0.500000 0.333333 0.166667
  3872. 0.166667 0.833333 0.000000 0.000000
  3873. 0.333333 0.000000 0.000000 0.666667
  3874. 0.666667 0.000000 0.000000 0.333333
  3875. 0.000000 0.500000 0.333333 0.166667
  3876. 0.166667 0.000000 0.333333 0.500000
  3877. 0.000000 0.333333 0.666667 0.000000
  3878. 0.000000 0.666667 0.000000 0.333333
  3879. 0.833333 0.000000 0.000000 0.166667
  3880. 0.833333 0.166667 0.000000 0.000000
  3881. 0.000000 0.833333 0.000000 0.166667
  3882. 0.666667 0.000000 0.166667 0.166667
  3883. 0.000000 0.500000 0.500000 0.000000
  3884. 0.000000 0.833333 0.166667 0.000000
  3885. 0.166667 0.000000 0.333333 0.500000
  3886. 0.000000 0.333333 0.333333 0.333333
  3887. 0.000000 0.666667 0.166667 0.166667
  3888. 0.333333 0.333333 0.333333 0.000000
  3889. 0.000000 0.333333 0.000000 0.666667
  3890. 0.166667 0.666667 0.166667 0.000000
  3891. 0.833333 0.000000 0.166667 0.000000
  3892. 1.000000 0.000000 0.000000 0.000000
  3893. 0.000000 0.666667 0.000000 0.333333
  3894. 0.000000 1.000000 0.000000 0.000000
  3895. 0.000000 1.000000 0.000000 0.000000
  3896. 0.000000 0.500000 0.166667 0.333333
  3897. 0.333333 0.500000 0.000000 0.166667
  3898. 0.000000 0.000000 0.000000 1.000000
  3899. 0.000000 0.500000 0.166667 0.333333
  3900. 0.333333 0.500000 0.166667 0.000000
  3901. 0.000000 0.000000 0.000000 1.000000
  3902. 0.000000 0.666667 0.166667 0.166667
  3903. 0.000000 0.000000 0.000000 1.000000
  3904. 1.000000 0.000000 0.000000 0.000000
  3905. 0.000000 0.333333 0.000000 0.666667
  3906. 0.166667 0.166667 0.666667 0.000000
  3907. 0.000000 0.500000 0.333333 0.166667
  3908. 0.166667 0.666667 0.000000 0.166667
  3909. 0.000000 0.333333 0.166667 0.500000
  3910. 0.000000 0.000000 0.166667 0.833333
  3911. 0.166667 0.666667 0.166667 0.000000
  3912. 0.166667 0.666667 0.000000 0.166667
  3913. --------------------------------------------------------------------------------
  3914.  
  3915. --------------------------------------------------------------------------------
  3916. Motif KNMTGGSCWWSKSYAACASCKBCVYCAAYCCYMTYMTCTAYGSCYTCC MEME-22 regular expression
  3917. --------------------------------------------------------------------------------
  3918. [GT][CG][CA]TGG[CG]C[TA][AT][CG][TG][GC][CT]AACA[CG]C[TG][CGT]C[ACG][TC]CAA[CT]CC[CT][CA]T[CT][CA]TCTA[TC]G[CG]C[TC]TCC
  3919. --------------------------------------------------------------------------------
  3920.  
  3921.  
  3922.  
  3923.  
  3924. Time 13430.11 secs.
  3925.  
  3926. ********************************************************************************
  3927.  
  3928.  
  3929. ********************************************************************************
  3930. MOTIF DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 width = 40 sites = 3 llr = 119 E-value = 6.1e+001
  3931. ********************************************************************************
  3932. --------------------------------------------------------------------------------
  3933. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 Description
  3934. --------------------------------------------------------------------------------
  3935. Simplified A 33:3::::::::7::::::::::3:::3::::377:::aa
  3936. pos.-specific C ::::::::::::::3::77:::::::::7::3::::::::
  3937. probability G 3737:a733a:a:a737337:a:7aa:33:7773:33a::
  3938. matrix T 3:7:a:377:a:3::73::3a:a:::a3:a3:::377:::
  3939.  
  3940. bits 2.1 * * * * * ** *
  3941. 1.9 ** *** * *** *** * ***
  3942. 1.7 ** *** * *** *** * ***
  3943. 1.5 ** *** * *** *** * ***
  3944. Relative 1.3 ** *** ** ** *** *** ** * ***
  3945. Entropy 1.1 *********** ************** ****** *****
  3946. (57.2 bits) 0.9 ************************** ************
  3947. 0.6 ************************** ************
  3948. 0.4 ****************************************
  3949. 0.2 ****************************************
  3950. 0.0 ----------------------------------------
  3951.  
  3952. Multilevel AGTGTGGTTGTGAGGTGCCGTGTGGGTACTGGGAATTGAA
  3953. consensus GAGA TGG T CGTGGT A GG TCAGTGG
  3954. sequence T T
  3955.  
  3956. --------------------------------------------------------------------------------
  3957.  
  3958. --------------------------------------------------------------------------------
  3959. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 sites sorted by position p-value
  3960. --------------------------------------------------------------------------------
  3961. Sequence name Strand Start P-value Site
  3962. ------------- ------ ----- --------- ----------------------------------------
  3963. Kiss1r + 6240 7.24e-20 GACTGGAGTT AATGTGGTTGTGAGGTTCCGTGTAGGTACTGGGAATGGAA CTAAGGCTCT
  3964. Htr6 + 8749 1.31e-19 ACTGGAGTTA TGGATGGTGGTGAGCTGCCTTGTGGGTTCTGGGAATTGAA CCAGGTCTTC
  3965. Npy2r - 6902 1.52e-17 CCCCCCCTCT GGTGTGTGTGTGTGGGGGGGTGTGGGTGGTTCAGTGTGAA CATCTGTGTC
  3966. --------------------------------------------------------------------------------
  3967.  
  3968. --------------------------------------------------------------------------------
  3969. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 block diagrams
  3970. --------------------------------------------------------------------------------
  3971. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  3972. ------------- ---------------- -------------
  3973. Kiss1r 7.2e-20 6239_[+23]_850
  3974. Htr6 1.3e-19 8748_[+23]_7029
  3975. Npy2r 1.5e-17 6901_[-23]_3666
  3976. --------------------------------------------------------------------------------
  3977.  
  3978. --------------------------------------------------------------------------------
  3979. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 in BLOCKS format
  3980. --------------------------------------------------------------------------------
  3981. BL MOTIF DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA width=40 seqs=3
  3982. Kiss1r ( 6240) AATGTGGTTGTGAGGTTCCGTGTAGGTACTGGGAATGGAA 1
  3983. Htr6 ( 8749) TGGATGGTGGTGAGCTGCCTTGTGGGTTCTGGGAATTGAA 1
  3984. Npy2r ( 6902) GGTGTGTGTGTGTGGGGGGGTGTGGGTGGTTCAGTGTGAA 1
  3985. //
  3986.  
  3987. --------------------------------------------------------------------------------
  3988.  
  3989. --------------------------------------------------------------------------------
  3990. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 position-specific scoring matrix
  3991. --------------------------------------------------------------------------------
  3992. log-odds matrix: alength= 4 w= 40 n= 110068 bayes= 14.822 E= 6.1e+001
  3993. 29 -823 55 29
  3994. 29 -823 155 -823
  3995. -823 -823 55 129
  3996. 29 -823 155 -823
  3997. -823 -823 -823 187
  3998. -823 -823 213 -823
  3999. -823 -823 155 29
  4000. -823 -823 55 129
  4001. -823 -823 55 129
  4002. -823 -823 213 -823
  4003. -823 -823 -823 187
  4004. -823 -823 213 -823
  4005. 129 -823 -823 29
  4006. -823 -823 213 -823
  4007. -823 55 155 -823
  4008. -823 -823 55 129
  4009. -823 -823 155 29
  4010. -823 155 55 -823
  4011. -823 155 55 -823
  4012. -823 -823 155 29
  4013. -823 -823 -823 187
  4014. -823 -823 213 -823
  4015. -823 -823 -823 187
  4016. 29 -823 155 -823
  4017. -823 -823 213 -823
  4018. -823 -823 213 -823
  4019. -823 -823 -823 187
  4020. 29 -823 55 29
  4021. -823 155 55 -823
  4022. -823 -823 -823 187
  4023. -823 -823 155 29
  4024. -823 55 155 -823
  4025. 29 -823 155 -823
  4026. 129 -823 55 -823
  4027. 129 -823 -823 29
  4028. -823 -823 55 129
  4029. -823 -823 55 129
  4030. -823 -823 213 -823
  4031. 187 -823 -823 -823
  4032. 187 -823 -823 -823
  4033. --------------------------------------------------------------------------------
  4034.  
  4035. --------------------------------------------------------------------------------
  4036. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 position-specific probability matrix
  4037. --------------------------------------------------------------------------------
  4038. letter-probability matrix: alength= 4 w= 40 nsites= 3 E= 6.1e+001
  4039. 0.333333 0.000000 0.333333 0.333333
  4040. 0.333333 0.000000 0.666667 0.000000
  4041. 0.000000 0.000000 0.333333 0.666667
  4042. 0.333333 0.000000 0.666667 0.000000
  4043. 0.000000 0.000000 0.000000 1.000000
  4044. 0.000000 0.000000 1.000000 0.000000
  4045. 0.000000 0.000000 0.666667 0.333333
  4046. 0.000000 0.000000 0.333333 0.666667
  4047. 0.000000 0.000000 0.333333 0.666667
  4048. 0.000000 0.000000 1.000000 0.000000
  4049. 0.000000 0.000000 0.000000 1.000000
  4050. 0.000000 0.000000 1.000000 0.000000
  4051. 0.666667 0.000000 0.000000 0.333333
  4052. 0.000000 0.000000 1.000000 0.000000
  4053. 0.000000 0.333333 0.666667 0.000000
  4054. 0.000000 0.000000 0.333333 0.666667
  4055. 0.000000 0.000000 0.666667 0.333333
  4056. 0.000000 0.666667 0.333333 0.000000
  4057. 0.000000 0.666667 0.333333 0.000000
  4058. 0.000000 0.000000 0.666667 0.333333
  4059. 0.000000 0.000000 0.000000 1.000000
  4060. 0.000000 0.000000 1.000000 0.000000
  4061. 0.000000 0.000000 0.000000 1.000000
  4062. 0.333333 0.000000 0.666667 0.000000
  4063. 0.000000 0.000000 1.000000 0.000000
  4064. 0.000000 0.000000 1.000000 0.000000
  4065. 0.000000 0.000000 0.000000 1.000000
  4066. 0.333333 0.000000 0.333333 0.333333
  4067. 0.000000 0.666667 0.333333 0.000000
  4068. 0.000000 0.000000 0.000000 1.000000
  4069. 0.000000 0.000000 0.666667 0.333333
  4070. 0.000000 0.333333 0.666667 0.000000
  4071. 0.333333 0.000000 0.666667 0.000000
  4072. 0.666667 0.000000 0.333333 0.000000
  4073. 0.666667 0.000000 0.000000 0.333333
  4074. 0.000000 0.000000 0.333333 0.666667
  4075. 0.000000 0.000000 0.333333 0.666667
  4076. 0.000000 0.000000 1.000000 0.000000
  4077. 1.000000 0.000000 0.000000 0.000000
  4078. 1.000000 0.000000 0.000000 0.000000
  4079. --------------------------------------------------------------------------------
  4080.  
  4081. --------------------------------------------------------------------------------
  4082. Motif DRKRTGKKKGTGWGSKKSSKTGTRGGTDSTKSRRWKKGAA MEME-23 regular expression
  4083. --------------------------------------------------------------------------------
  4084. [AGT][GA][TG][GA]TG[GT][TG][TG]GTG[AT]G[GC][TG][GT][CG][CG][GT]TGT[GA]GGT[AGT][CG]T[GT][GC][GA][AG][AT][TG][TG]GAA
  4085. --------------------------------------------------------------------------------
  4086.  
  4087.  
  4088.  
  4089.  
  4090. Time 14058.61 secs.
  4091.  
  4092. ********************************************************************************
  4093.  
  4094.  
  4095. ********************************************************************************
  4096. MOTIF TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 width = 40 sites = 6 llr = 188 E-value = 5.2e+000
  4097. ********************************************************************************
  4098. --------------------------------------------------------------------------------
  4099. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 Description
  4100. --------------------------------------------------------------------------------
  4101. Simplified A ::::32::2232::::5aa:::3322::38:::52:::3:
  4102. pos.-specific C :38:::23222223:25::7:a352:3:3:28223233::
  4103. probability G :72:58853:37:5a8::::::3::87:3:::2228:37:
  4104. matrix T a::a2::2372:82:::::3a::27::a:282723:73:a
  4105.  
  4106. bits 2.1 * *
  4107. 1.9 * * * ** ** * *
  4108. 1.7 * * * ** ** * *
  4109. 1.5 * ** ** ** ** ** * * * * *
  4110. Relative 1.3 **** ** * ** ** ** *** *** * *
  4111. Entropy 1.1 **** ** * ******** *** *** ** **
  4112. (45.3 bits) 0.9 **** ** ** ******** *** *** ** **
  4113. 0.6 ******** * *********** ***** **** ** **
  4114. 0.4 ******** * ********************** *****
  4115. 0.2 ******** * *********************** *****
  4116. 0.0 ----------------------------------------
  4117.  
  4118. Multilevel TGCTGGGGGTAGTGGGAAACTCACTGGTAATCTACGTCGT
  4119. consensus C A CT G C C T CA C C T CGA
  4120. sequence G G T
  4121.  
  4122. --------------------------------------------------------------------------------
  4123.  
  4124. --------------------------------------------------------------------------------
  4125. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 sites sorted by position p-value
  4126. --------------------------------------------------------------------------------
  4127. Sequence name Strand Start P-value Site
  4128. ------------- ------ ----- --------- ----------------------------------------
  4129. Npy2r + 7708 1.18e-18 TCCATCATCT TGCTAGGGGTAGTTGGCAACTCCCTGGTAATCCATGTGGT AATCAAATTC
  4130. Sstr3 + 8994 7.19e-18 GTGGTGTGCG TGGTGGGTTTGCTGGGCAACTCGCTGGTGATCTACGTGGT CCTGCGGCAC
  4131. Kiss1r + 1875 1.66e-17 ACACTCATGT TGCTTGGGCTGGTCGGAAACTCATTGGTCATCTACGTTAT CTGCCGCCAC
  4132. Mchr1 + 1707 1.21e-14 ACCATCTGTC TCCTGGGCATTGTGGGAAACTCCACAGTCATTTTTGCCGT GGTGAAGAAA
  4133. Arl13b + 25425 3.46e-13 TTGTAGGCTA TCCTAGGCTACATGGGAAATTCAAAGCTATCCTGAGCTGT ATAGTAAGAA
  4134. Htr6 + 873 4.10e-13 GTGGTCATCG TGCTGACGGCAGCCGCCAATTCGCTGCTGATCGCGCTCAT CTGCACGCAG
  4135. --------------------------------------------------------------------------------
  4136.  
  4137. --------------------------------------------------------------------------------
  4138. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 block diagrams
  4139. --------------------------------------------------------------------------------
  4140. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  4141. ------------- ---------------- -------------
  4142. Npy2r 1.2e-18 7707_[+24]_2860
  4143. Sstr3 7.2e-18 8993_[+24]_3323
  4144. Kiss1r 1.7e-17 1874_[+24]_5215
  4145. Mchr1 1.2e-14 1706_[+24]_1720
  4146. Arl13b 3.5e-13 25424_[+24]_28282
  4147. Htr6 4.1e-13 872_[+24]_14905
  4148. --------------------------------------------------------------------------------
  4149.  
  4150. --------------------------------------------------------------------------------
  4151. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 in BLOCKS format
  4152. --------------------------------------------------------------------------------
  4153. BL MOTIF TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT width=40 seqs=6
  4154. Npy2r ( 7708) TGCTAGGGGTAGTTGGCAACTCCCTGGTAATCCATGTGGT 1
  4155. Sstr3 ( 8994) TGGTGGGTTTGCTGGGCAACTCGCTGGTGATCTACGTGGT 1
  4156. Kiss1r ( 1875) TGCTTGGGCTGGTCGGAAACTCATTGGTCATCTACGTTAT 1
  4157. Mchr1 ( 1707) TCCTGGGCATTGTGGGAAACTCCACAGTCATTTTTGCCGT 1
  4158. Arl13b ( 25425) TCCTAGGCTACATGGGAAATTCAAAGCTATCCTGAGCTGT 1
  4159. Htr6 ( 873) TGCTGACGGCAGCCGCCAATTCGCTGCTGATCGCGCTCAT 1
  4160. //
  4161.  
  4162. --------------------------------------------------------------------------------
  4163.  
  4164. --------------------------------------------------------------------------------
  4165. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 position-specific scoring matrix
  4166. --------------------------------------------------------------------------------
  4167. log-odds matrix: alength= 4 w= 40 n= 110068 bayes= 14.6105 E= 5.2e+000
  4168. -923 -923 -923 187
  4169. -923 55 155 -923
  4170. -923 187 -45 -923
  4171. -923 -923 -923 187
  4172. 29 -923 113 -71
  4173. -71 -923 187 -923
  4174. -923 -45 187 -923
  4175. -923 55 113 -71
  4176. -71 -45 55 29
  4177. -71 -45 -923 129
  4178. 29 -45 55 -71
  4179. -71 -45 155 -923
  4180. -923 -45 -923 161
  4181. -923 55 113 -71
  4182. -923 -923 213 -923
  4183. -923 -45 187 -923
  4184. 88 113 -923 -923
  4185. 187 -923 -923 -923
  4186. 187 -923 -923 -923
  4187. -923 155 -923 29
  4188. -923 -923 -923 187
  4189. -923 213 -923 -923
  4190. 29 55 55 -923
  4191. 29 113 -923 -71
  4192. -71 -45 -923 129
  4193. -71 -923 187 -923
  4194. -923 55 155 -923
  4195. -923 -923 -923 187
  4196. 29 55 55 -923
  4197. 161 -923 -923 -71
  4198. -923 -45 -923 161
  4199. -923 187 -923 -71
  4200. -923 -45 -45 129
  4201. 88 -45 -45 -71
  4202. -71 55 -45 29
  4203. -923 -45 187 -923
  4204. -923 55 -923 129
  4205. -923 55 55 29
  4206. 29 -923 155 -923
  4207. -923 -923 -923 187
  4208. --------------------------------------------------------------------------------
  4209.  
  4210. --------------------------------------------------------------------------------
  4211. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 position-specific probability matrix
  4212. --------------------------------------------------------------------------------
  4213. letter-probability matrix: alength= 4 w= 40 nsites= 6 E= 5.2e+000
  4214. 0.000000 0.000000 0.000000 1.000000
  4215. 0.000000 0.333333 0.666667 0.000000
  4216. 0.000000 0.833333 0.166667 0.000000
  4217. 0.000000 0.000000 0.000000 1.000000
  4218. 0.333333 0.000000 0.500000 0.166667
  4219. 0.166667 0.000000 0.833333 0.000000
  4220. 0.000000 0.166667 0.833333 0.000000
  4221. 0.000000 0.333333 0.500000 0.166667
  4222. 0.166667 0.166667 0.333333 0.333333
  4223. 0.166667 0.166667 0.000000 0.666667
  4224. 0.333333 0.166667 0.333333 0.166667
  4225. 0.166667 0.166667 0.666667 0.000000
  4226. 0.000000 0.166667 0.000000 0.833333
  4227. 0.000000 0.333333 0.500000 0.166667
  4228. 0.000000 0.000000 1.000000 0.000000
  4229. 0.000000 0.166667 0.833333 0.000000
  4230. 0.500000 0.500000 0.000000 0.000000
  4231. 1.000000 0.000000 0.000000 0.000000
  4232. 1.000000 0.000000 0.000000 0.000000
  4233. 0.000000 0.666667 0.000000 0.333333
  4234. 0.000000 0.000000 0.000000 1.000000
  4235. 0.000000 1.000000 0.000000 0.000000
  4236. 0.333333 0.333333 0.333333 0.000000
  4237. 0.333333 0.500000 0.000000 0.166667
  4238. 0.166667 0.166667 0.000000 0.666667
  4239. 0.166667 0.000000 0.833333 0.000000
  4240. 0.000000 0.333333 0.666667 0.000000
  4241. 0.000000 0.000000 0.000000 1.000000
  4242. 0.333333 0.333333 0.333333 0.000000
  4243. 0.833333 0.000000 0.000000 0.166667
  4244. 0.000000 0.166667 0.000000 0.833333
  4245. 0.000000 0.833333 0.000000 0.166667
  4246. 0.000000 0.166667 0.166667 0.666667
  4247. 0.500000 0.166667 0.166667 0.166667
  4248. 0.166667 0.333333 0.166667 0.333333
  4249. 0.000000 0.166667 0.833333 0.000000
  4250. 0.000000 0.333333 0.000000 0.666667
  4251. 0.000000 0.333333 0.333333 0.333333
  4252. 0.333333 0.000000 0.666667 0.000000
  4253. 0.000000 0.000000 0.000000 1.000000
  4254. --------------------------------------------------------------------------------
  4255.  
  4256. --------------------------------------------------------------------------------
  4257. Motif TSCTRGGSNTNGTSGGMAAYTCVMTGSTVATCTANGYBRT MEME-24 regular expression
  4258. --------------------------------------------------------------------------------
  4259. T[GC]CT[GA]GG[GC][GT]T[AG]GT[GC]GG[AC]AA[CT]TC[ACG][CA]TG[GC]T[ACG]ATCTA[CT]G[TC][CGT][GA]T
  4260. --------------------------------------------------------------------------------
  4261.  
  4262.  
  4263.  
  4264.  
  4265. Time 14685.91 secs.
  4266.  
  4267. ********************************************************************************
  4268.  
  4269.  
  4270. ********************************************************************************
  4271. MOTIF TGKGTGTGTGYGTGT MEME-25 width = 15 sites = 7 llr = 119 E-value = 9.6e+001
  4272. ********************************************************************************
  4273. --------------------------------------------------------------------------------
  4274. Motif TGKGTGTGTGYGTGT MEME-25 Description
  4275. --------------------------------------------------------------------------------
  4276. Simplified A ::::::1:::13:::
  4277. pos.-specific C ::::::::::3::::
  4278. probability G :a4a:a1a:a:719:
  4279. matrix T a:6:a:7:a:6:91a
  4280.  
  4281. bits 2.1 * * * * *
  4282. 1.9 ** *** *** *
  4283. 1.7 ** *** *** *
  4284. 1.5 ** *** *** **
  4285. Relative 1.3 ** *** *** ****
  4286. Entropy 1.1 ****** *** ****
  4287. (24.5 bits) 0.9 ********** ****
  4288. 0.6 ***************
  4289. 0.4 ***************
  4290. 0.2 ***************
  4291. 0.0 ---------------
  4292.  
  4293. Multilevel TGTGTGTGTGTGTGT
  4294. consensus G CA
  4295. sequence
  4296.  
  4297. --------------------------------------------------------------------------------
  4298.  
  4299. --------------------------------------------------------------------------------
  4300. Motif TGKGTGTGTGYGTGT MEME-25 sites sorted by position p-value
  4301. --------------------------------------------------------------------------------
  4302. Sequence name Strand Start P-value Site
  4303. ------------- ------ ----- --------- ---------------
  4304. Npy2r - 6712 9.60e-10 CTGTTCATGT TGTGTGTGTGTGTGT ATGTGTGTTT
  4305. Arl13b + 13660 9.60e-10 TGTGTGTCTC TGTGTGTGTGTGTGT GTGTCTGTGT
  4306. Sstr3 + 8584 1.76e-09 CCCTGGAGTT TGGGTGTGTGTGTGT TGAGGGTCTC
  4307. Htr6 + 4509 2.57e-09 TGATGATGTG TGTGTGTGTGCGTGT ACACACACAC
  4308. Kiss1r + 3865 3.24e-08 CCTCAGCATC TGGGTGGGTGAGTGT GGTTGGGGTC
  4309. Mchr1 - 1202 3.44e-08 TGTGTGTGTG TGTGTGTGTGTATTT GCAGCCTCAT
  4310. Mc4r - 668 9.16e-08 AAAAAGTACA TGGGTGAGTGCAGGT TCTTGTTCTT
  4311. --------------------------------------------------------------------------------
  4312.  
  4313. --------------------------------------------------------------------------------
  4314. Motif TGKGTGTGTGYGTGT MEME-25 block diagrams
  4315. --------------------------------------------------------------------------------
  4316. SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM
  4317. ------------- ---------------- -------------
  4318. Npy2r 9.6e-10 6711_[-25]_3881
  4319. Arl13b 9.6e-10 13659_[+25]_40072
  4320. Sstr3 1.8e-09 8583_[+25]_3758
  4321. Htr6 2.6e-09 4508_[+25]_11294
  4322. Kiss1r 3.2e-08 3864_[+25]_3250
  4323. Mchr1 3.4e-08 1201_[-25]_2250
  4324. Mc4r 9.2e-08 667_[-25]_2101
  4325. --------------------------------------------------------------------------------
  4326.  
  4327. --------------------------------------------------------------------------------
  4328. Motif TGKGTGTGTGYGTGT MEME-25 in BLOCKS format
  4329. --------------------------------------------------------------------------------
  4330. BL MOTIF TGKGTGTGTGYGTGT width=15 seqs=7
  4331. Npy2r ( 6712) TGTGTGTGTGTGTGT 1
  4332. Arl13b ( 13660) TGTGTGTGTGTGTGT 1
  4333. Sstr3 ( 8584) TGGGTGTGTGTGTGT 1
  4334. Htr6 ( 4509) TGTGTGTGTGCGTGT 1
  4335. Kiss1r ( 3865) TGGGTGGGTGAGTGT 1
  4336. Mchr1 ( 1202) TGTGTGTGTGTATTT 1
  4337. Mc4r ( 668) TGGGTGAGTGCAGGT 1
  4338. //
  4339.  
  4340. --------------------------------------------------------------------------------
  4341.  
  4342. --------------------------------------------------------------------------------
  4343. Motif TGKGTGTGTGYGTGT MEME-25 position-specific scoring matrix
  4344. --------------------------------------------------------------------------------
  4345. log-odds matrix: alength= 4 w= 15 n= 110268 bayes= 13.9432 E= 9.6e+001
  4346. -945 -945 -945 187
  4347. -945 -945 213 -945
  4348. -945 -945 91 107
  4349. -945 -945 213 -945
  4350. -945 -945 -945 187
  4351. -945 -945 213 -945
  4352. -93 -945 -67 139
  4353. -945 -945 213 -945
  4354. -945 -945 -945 187
  4355. -945 -945 213 -945
  4356. -93 33 -945 107
  4357. 7 -945 165 -945
  4358. -945 -945 -67 165
  4359. -945 -945 191 -93
  4360. -945 -945 -945 187
  4361. --------------------------------------------------------------------------------
  4362.  
  4363. --------------------------------------------------------------------------------
  4364. Motif TGKGTGTGTGYGTGT MEME-25 position-specific probability matrix
  4365. --------------------------------------------------------------------------------
  4366. letter-probability matrix: alength= 4 w= 15 nsites= 7 E= 9.6e+001
  4367. 0.000000 0.000000 0.000000 1.000000
  4368. 0.000000 0.000000 1.000000 0.000000
  4369. 0.000000 0.000000 0.428571 0.571429
  4370. 0.000000 0.000000 1.000000 0.000000
  4371. 0.000000 0.000000 0.000000 1.000000
  4372. 0.000000 0.000000 1.000000 0.000000
  4373. 0.142857 0.000000 0.142857 0.714286
  4374. 0.000000 0.000000 1.000000 0.000000
  4375. 0.000000 0.000000 0.000000 1.000000
  4376. 0.000000 0.000000 1.000000 0.000000
  4377. 0.142857 0.285714 0.000000 0.571429
  4378. 0.285714 0.000000 0.714286 0.000000
  4379. 0.000000 0.000000 0.142857 0.857143
  4380. 0.000000 0.000000 0.857143 0.142857
  4381. 0.000000 0.000000 0.000000 1.000000
  4382. --------------------------------------------------------------------------------
  4383.  
  4384. --------------------------------------------------------------------------------
  4385. Motif TGKGTGTGTGYGTGT MEME-25 regular expression
  4386. --------------------------------------------------------------------------------
  4387. TG[TG]GTGTGTG[TC][GA]TGT
  4388. --------------------------------------------------------------------------------
  4389.  
  4390.  
  4391.  
  4392.  
  4393. Time 15315.30 secs.
  4394.  
  4395. ********************************************************************************
  4396.  
  4397.  
  4398. ********************************************************************************
  4399. SUMMARY OF MOTIFS
  4400. ********************************************************************************
  4401.  
  4402. --------------------------------------------------------------------------------
  4403. Combined block diagrams: non-overlapping sites with p-value < 0.0001
  4404. --------------------------------------------------------------------------------
  4405. SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM
  4406. ------------- ---------------- -------------
  4407. Kiss1r 0.00e+00 33_[+2(5.39e-05)]_26_\
  4408. [+16(2.63e-05)]_21_[-13(1.00e-05)]_23_[+8(2.21e-05)]_16_[+19(9.92e-05)]_27_\
  4409. [-3(8.95e-05)]_9_[+20(5.78e-05)]_[+16(1.15e-05)]_3_[-14(6.17e-05)]_28_\
  4410. [-4(1.61e-06)]_113_[-3(7.41e-06)]_31_[+21(5.36e-05)]_40_[+13(2.53e-05)]_41_\
  4411. [-8(5.73e-06)]_22_[-2(8.27e-05)]_89_[+23(5.54e-05)]_44_[-14(6.17e-05)]_107_\
  4412. [+13(5.66e-05)]_12_[-12(5.41e-08)]_7_[+21(2.99e-05)]_20_[+12(6.19e-08)]_38_\
  4413. [+19(6.54e-05)]_6_[+16(5.84e-05)]_5_[+4(2.45e-06)]_20_[+8(4.72e-12)]_63_\
  4414. [-11(5.39e-05)]_13_[-11(3.90e-05)]_11_[+24(1.66e-17)]_41_[+25(1.62e-05)]_\
  4415. 54_[+5(1.61e-05)]_60_[+15(4.32e-05)]_2_[+23(2.35e-05)]_59_[-3(1.78e-05)]_\
  4416. 33_[-19(3.31e-05)]_31_[-12(2.62e-05)]_51_[+13(4.39e-07)]_33_\
  4417. [-13(1.66e-05)]_21_[-3(2.66e-15)]_24_[+2(2.26e-05)]_23_[+2(4.43e-18)]_75_\
  4418. [-4(3.67e-07)]_38_[+7(1.26e-11)]_44_[+19(5.50e-05)]_38_[+16(3.97e-22)]_46_\
  4419. [+21(1.77e-05)]_17_[-13(1.00e-04)]_26_[-13(1.02e-15)]_7_[+23(7.35e-05)]_31_\
  4420. [+2(9.05e-05)]_53_[+13(5.66e-05)]_[-8(2.66e-05)]_6_[-12(1.19e-05)]_116_\
  4421. [+10(3.19e-19)]_55_[+25(3.24e-08)]_61_[+12(7.59e-07)]_23_[+13(3.00e-05)]_\
  4422. 44_[-12(3.14e-05)]_29_[-21(1.15e-05)]_22_[+13(2.30e-05)]_4_[+19(1.70e-05)]_\
  4423. 3_[+12(4.33e-06)]_29_[-1(1.42e-30)]_35_[+23(1.03e-05)]_35_[+23(3.12e-06)]_\
  4424. 44_[-16(7.19e-05)]_16_[+5(4.70e-22)]_32_[+5(6.84e-05)]_6_[+22(1.20e-17)]_\
  4425. 35_[+13(1.12e-05)]_107_[+18(1.55e-05)]_80_[-11(2.24e-05)]_30_\
  4426. [-8(2.72e-05)]_78_[-21(3.75e-12)]_28_[-11(6.23e-05)]_126_[+20(7.84e-17)]_\
  4427. 54_[-9(1.15e-20)]_13_[+11(2.51e-18)]_49_[+18(2.07e-24)]_20_[+25(6.02e-05)]_\
  4428. 55_[-25(1.21e-05)]_22_[+4(3.18e-23)]_37_[+14(6.66e-23)]_61_[+18(7.20e-08)]_\
  4429. [+19(3.43e-05)]_45_[+23(7.24e-20)]_8_[+6(1.04e-24)]_43_[+15(2.97e-20)]_2_\
  4430. [+14(2.47e-05)]_5_[-21(2.56e-05)]_42_[-20(4.36e-06)]_123_[-3(5.16e-05)]_21_\
  4431. [-18(7.56e-06)]_49_[-12(1.33e-16)]_217
  4432. Mc4r 3.51e-97 53_[-13(4.25e-15)]_62_\
  4433. [-3(1.29e-13)]_104_[+9(2.77e-05)]_8_[-2(1.52e-14)]_48_[+19(8.48e-10)]_14_\
  4434. [-21(5.69e-10)]_21_[+12(1.99e-05)]_14_[+7(1.09e-10)]_53_[-25(9.16e-08)]_6_\
  4435. [+17(1.67e-16)]_79_[+17(7.01e-05)]_12_[+10(9.91e-17)]_24_[-20(1.49e-12)]_8_\
  4436. [+9(1.03e-12)]_29_[-8(1.30e-05)]_102_[+5(6.82e-20)]_8_[-8(1.53e-05)]_41_\
  4437. [+22(1.26e-16)]_89_[+8(2.79e-05)]_262_[+3(4.83e-05)]_233_[+8(1.49e-10)]_36_\
  4438. [-5(3.29e-05)]_225_[-4(9.05e-06)]_70_[+23(5.43e-05)]_123_[+24(7.74e-05)]_\
  4439. 117
  4440. Arl13b 1.58e-241 35_[+6(7.96e-05)]_16_\
  4441. [-11(6.48e-05)]_26_[+3(2.10e-05)]_2_[+12(6.70e-05)]_36_[-19(7.07e-06)]_54_\
  4442. [+21(5.13e-05)]_56_[+12(5.41e-06)]_25_[+22(5.46e-05)]_46_[+23(2.45e-06)]_\
  4443. 36_[+23(3.55e-05)]_11_[-25(1.42e-05)]_45_[+3(5.97e-05)]_260_\
  4444. [-10(2.91e-05)]_278_[+19(5.09e-06)]_550_[+3(5.15e-19)]_236_[+8(8.53e-06)]_\
  4445. 262_[-14(2.98e-05)]_343_[+25(9.60e-10)]_488_[-14(2.83e-05)]_49_\
  4446. [-19(2.29e-06)]_156_[-17(2.63e-05)]_262_[+23(7.70e-05)]_14_[+3(1.69e-05)]_\
  4447. 22_[+24(9.41e-05)]_36_[+18(1.87e-05)]_87_[+3(6.17e-05)]_93_[-21(3.26e-05)]_\
  4448. 141_[+3(4.16e-06)]_164_[+3(4.16e-06)]_1_[+3(1.63e-05)]_133_[-15(8.32e-05)]_\
  4449. 229_[-1(9.79e-11)]_144_[-10(3.00e-05)]_109_[-4(9.68e-05)]_127_\
  4450. [+12(4.64e-05)]_146_[+7(3.63e-06)]_83_[+8(8.51e-05)]_161_[+17(6.56e-05)]_\
  4451. 32_[-7(8.01e-05)]_13_[+3(2.77e-06)]_491_[+4(3.70e-05)]_176_[+23(3.14e-05)]_\
  4452. 5_[+6(1.38e-07)]_277_[+4(9.44e-05)]_109_[-24(9.97e-06)]_8_[+4(5.49e-05)]_1_\
  4453. [+21(1.73e-05)]_6_[-19(6.54e-05)]_139_[+4(2.57e-08)]_84_[-3(1.11e-05)]_8_\
  4454. [+2(3.17e-05)]_30_[+24(4.16e-05)]_61_[-21(8.34e-06)]_208_[+9(3.25e-08)]_56_\
  4455. [-21(9.70e-05)]_15_[+19(8.70e-12)]_26_[+17(3.85e-05)]_139_[-11(7.90e-05)]_\
  4456. 18_[+4(4.77e-05)]_124_[-14(1.92e-05)]_101_[-1(3.86e-20)]_80_\
  4457. [+25(9.33e-05)]_6_[-18(8.44e-06)]_46_[+4(7.30e-07)]_14_[+20(2.95e-05)]_11_\
  4458. [+7(1.01e-05)]_177_[+3(1.15e-05)]_49_[-20(7.12e-05)]_456_[-10(6.88e-05)]_\
  4459. 159_[-21(9.11e-05)]_177_[-8(1.61e-06)]_18_[+3(5.15e-19)]_3_[+3(1.94e-14)]_\
  4460. 86_[-9(7.12e-05)]_7_[+16(1.02e-19)]_19_[+17(3.67e-05)]_457_[-6(4.65e-13)]_\
  4461. 9_[-23(3.64e-07)]_1_[+16(5.61e-05)]_25_[-7(2.20e-06)]_52_[-7(8.68e-05)]_\
  4462. 149_[+23(9.35e-05)]_[+10(5.93e-05)]_3_[-18(3.21e-05)]_76_[+1(5.77e-05)]_89_\
  4463. [+25(9.33e-05)]_203_[-8(2.72e-05)]_57_[+7(2.81e-07)]_79_[-8(1.60e-05)]_132_\
  4464. [+25(1.89e-06)]_160_[+2(4.59e-23)]_7_[+2(5.49e-20)]_[+25(1.78e-07)]_7_\
  4465. [+1(3.27e-30)]_10_[+1(3.27e-30)]_2_[+1(7.46e-28)]_[+7(1.36e-09)]_\
  4466. [+2(2.68e-28)]_1_[+2(1.41e-16)]_[+1(5.14e-26)]_4_[+1(6.51e-26)]_\
  4467. [+25(5.24e-06)]_7_[+1(3.63e-26)]_[+25(1.78e-07)]_1_[+1(5.14e-26)]_\
  4468. [+7(7.60e-16)]_19_[+23(6.26e-05)]_12_[-17(4.88e-05)]_242_[-6(3.74e-05)]_37_\
  4469. [-14(3.85e-05)]_28_[+19(6.79e-06)]_130_[-8(2.79e-05)]_14_[-20(5.02e-05)]_\
  4470. 132_[-23(4.18e-05)]_27_[+17(9.15e-05)]_202_[+13(8.04e-06)]_36_\
  4471. [+7(2.04e-05)]_202_[+6(5.01e-05)]_279_[-8(8.32e-07)]_649_[-8(3.05e-05)]_9_\
  4472. [+12(3.52e-06)]_134_[+14(6.66e-06)]_1_[+5(8.07e-05)]_261_[+3(3.92e-06)]_32_\
  4473. [-8(2.79e-05)]_52_[-8(3.19e-05)]_159_[+13(1.02e-05)]_32_[+8(4.80e-05)]_70_\
  4474. [+12(3.73e-05)]_31_[-8(3.54e-06)]_28_[+23(7.59e-05)]_9_[-20(8.57e-05)]_412_\
  4475. [-14(7.37e-05)]_66_[+11(2.24e-05)]_130_[+10(9.91e-05)]_24_[+10(9.91e-05)]_\
  4476. 70_[-23(5.90e-05)]_390_[-14(1.27e-08)]_20_[-4(3.23e-13)]_5_[-7(1.14e-05)]_\
  4477. 69_[+1(7.50e-09)]_28_[+15(6.10e-25)]_5_[+9(1.30e-22)]_57_[+17(4.43e-05)]_\
  4478. 293_[+8(2.79e-06)]_249_[-18(1.62e-05)]_61_[+14(2.47e-06)]_21_\
  4479. [+3(3.87e-05)]_65_[+14(1.39e-05)]_37_[+13(1.31e-05)]_62_[-8(1.30e-05)]_139_\
  4480. [-10(8.33e-05)]_402_[+25(2.78e-05)]_15_[-8(7.82e-05)]_235_[+3(3.29e-07)]_3_\
  4481. [+3(3.13e-06)]_21_[-8(8.97e-05)]_65_[+5(3.13e-06)]_363_[+3(1.49e-05)]_22_\
  4482. [-7(4.50e-05)]_131_[+3(1.65e-08)]_6_[-8(2.01e-07)]_[+4(1.67e-09)]_66_\
  4483. [+9(3.04e-05)]_[+23(2.60e-05)]_25_[+25(5.31e-05)]_443_[-6(8.16e-26)]_8_\
  4484. [-23(1.66e-11)]_89_[-23(8.89e-07)]_72_[-17(5.65e-05)]_33_[-13(7.77e-07)]_\
  4485. 25_[+8(8.81e-05)]_17_[+7(2.28e-05)]_176_[+17(6.67e-05)]_31_[-8(7.82e-05)]_\
  4486. 77_[-14(6.50e-05)]_183_[-4(7.03e-05)]_7_[+2(7.18e-06)]_47_[-25(3.57e-05)]_\
  4487. 73_[+20(7.51e-06)]_88_[-8(2.42e-05)]_261_[-22(6.71e-05)]_69_\
  4488. [+17(6.90e-05)]_66_[-20(9.18e-06)]_25_[+15(3.66e-05)]_10_[-15(3.36e-05)]_\
  4489. 42_[+14(2.08e-05)]_12_[+23(9.67e-05)]_2_[+18(4.76e-06)]_60_[+24(3.46e-13)]_\
  4490. 27_[-3(9.86e-08)]_45_[-20(5.86e-06)]_36_[+12(4.54e-08)]_10_[+12(3.90e-18)]_\
  4491. 100_[-6(8.08e-05)]_72_[+17(6.90e-05)]_115_[-6(6.60e-10)]_15_\
  4492. [-23(2.69e-09)]_69_[-7(1.22e-05)]_337_[-25(1.43e-06)]_292_[-14(3.49e-05)]_\
  4493. 16_[-1(2.14e-22)]_276_[-7(8.33e-05)]_224_[+7(1.57e-05)]_6_[+3(2.27e-12)]_\
  4494. 126_[-20(8.01e-05)]_41_[+8(7.19e-05)]_25_[+18(1.71e-06)]_243_\
  4495. [-19(1.70e-05)]_157_[-7(4.26e-06)]_96_[+23(2.10e-08)]_130_[+7(1.68e-05)]_\
  4496. 12_[-18(1.34e-21)]_242_[+25(4.69e-05)]_262_[+23(1.77e-05)]_43_\
  4497. [+8(1.31e-06)]_27_[+4(9.80e-05)]_108_[-16(9.39e-05)]_65_[+1(5.84e-06)]_\
  4498. [+4(6.80e-06)]_12_[+9(1.95e-09)]_121_[-11(7.06e-05)]_10_[+2(5.39e-07)]_292_\
  4499. [-6(4.79e-05)]_63_[+8(6.63e-05)]_109_[-9(5.11e-06)]_8_[-15(5.99e-14)]_36_\
  4500. [-3(3.99e-11)]_9_[-1(2.10e-10)]_1_[+8(2.26e-05)]_677_[-4(9.84e-05)]_329_\
  4501. [+7(1.96e-05)]_26_[-1(5.14e-26)]_[-3(5.15e-19)]_2_[+8(1.61e-06)]_118_\
  4502. [+20(3.42e-05)]_292_[-3(4.29e-05)]_147_[+2(9.32e-05)]_232_[+3(2.05e-07)]_\
  4503. 242_[-3(1.13e-05)]_11_[+21(3.72e-05)]_150_[+17(9.59e-15)]_186_\
  4504. [-8(1.13e-05)]_50_[+2(4.27e-05)]_133_[-16(2.05e-05)]_48_[+13(4.18e-05)]_\
  4505. 181_[+23(1.42e-05)]_184_[-18(8.47e-05)]_18_[+4(4.25e-08)]_5_\
  4506. [+14(4.17e-07)]_200_[+1(6.14e-05)]_139_[-22(6.51e-05)]_27_[-3(1.51e-06)]_\
  4507. 122_[+7(3.78e-05)]_474_[+1(5.71e-06)]_134_[-12(2.75e-06)]_12_\
  4508. [+22(1.48e-05)]_117_[+17(3.29e-05)]_61_[-21(7.95e-13)]_3_[+13(9.66e-05)]_\
  4509. 23_[-19(7.70e-06)]_74_[-17(4.80e-05)]_117_[+13(7.88e-06)]_91_\
  4510. [+7(4.59e-05)]_141_[+17(4.04e-05)]_121_[+12(4.56e-05)]_52_[-20(3.24e-06)]_\
  4511. 70_[-13(5.14e-14)]_125_[+3(5.87e-06)]_297_[+25(7.11e-05)]_25_\
  4512. [-18(1.47e-05)]_42_[+1(8.23e-06)]_13_[+5(8.53e-05)]_104_[-22(1.55e-08)]_\
  4513. 128_[-3(2.10e-05)]_92_[+25(3.77e-05)]_55_[+23(3.30e-05)]_195_\
  4514. [+7(6.55e-05)]_136_[-17(1.82e-05)]_52_[+14(1.09e-05)]_60_[-8(4.45e-05)]_87_\
  4515. [+21(6.77e-05)]_25_[+20(9.32e-05)]_81_[-17(4.96e-05)]_36_[-21(1.43e-05)]_\
  4516. 81_[-11(6.72e-06)]_212_[+14(3.62e-05)]_137_[+3(2.22e-05)]_398_\
  4517. [-13(5.97e-05)]_108_[+16(3.70e-05)]_31_[-4(9.46e-05)]_62_[+17(1.31e-05)]_\
  4518. 447_[+21(1.04e-05)]_138_[-19(3.71e-05)]_95_[-3(4.01e-05)]_96_\
  4519. [-2(1.12e-05)]_79_[-25(1.36e-08)]_233_[-23(4.39e-06)]_6_[-8(5.36e-06)]_6_\
  4520. [-9(3.46e-05)]_455_[+1(1.98e-07)]_239_[+20(1.11e-06)]_126_[-13(1.66e-05)]_\
  4521. [+24(8.39e-05)]_356_[+17(7.76e-05)]_140_[+2(1.20e-05)]_11_[+3(2.40e-06)]_\
  4522. 342_[-3(5.59e-05)]_33_[-12(3.66e-08)]_53_[+8(1.92e-06)]_266_[+7(5.37e-05)]_\
  4523. 56_[-18(1.44e-05)]_39_[+9(7.99e-05)]_158_[+15(7.24e-05)]_157_\
  4524. [+24(4.55e-05)]_306_[-15(6.65e-05)]_556_[+10(7.74e-05)]_240_[-7(1.83e-05)]_\
  4525. 13_[-16(2.41e-05)]_154_[-4(1.43e-05)]_9_[+16(2.91e-06)]_53_[-25(2.54e-05)]_\
  4526. 359_[-12(7.86e-05)]_7_[+15(9.40e-05)]_51_[+3(2.06e-05)]_31_[+14(5.11e-05)]_\
  4527. 18_[+14(3.76e-05)]_67_[+3(4.29e-05)]_209_[-8(2.60e-05)]_6_[-2(2.41e-05)]_\
  4528. 108_[-16(1.02e-05)]_99_[+24(1.82e-05)]_25_[+11(2.30e-05)]_88_\
  4529. [-19(8.39e-05)]_224_[-3(2.71e-05)]_88_[-3(1.67e-06)]_215_[+25(9.85e-06)]_\
  4530. 116_[-18(8.13e-10)]_456_[-14(1.99e-22)]_6_[+20(5.52e-20)]_10_\
  4531. [-1(1.12e-05)]_481_[+9(9.55e-05)]_369_[-7(6.29e-05)]_70_[-16(1.56e-05)]_\
  4532. 334_[+3(1.05e-05)]_65_[+22(8.23e-05)]_76_[+23(7.70e-05)]_788_\
  4533. [+19(5.00e-07)]_20_[+5(2.06e-05)]_38_[+21(9.30e-05)]_101_[+10(2.48e-05)]_\
  4534. 279_[+25(3.01e-05)]_664_[+16(2.17e-11)]_188
  4535. Drd1 2.20e-27 6_[-9(4.23e-13)]_[+12(1.14e-05)]_11_\
  4536. [+5(5.44e-05)]_39_[-19(2.08e-06)]_129_[+8(3.44e-06)]_31_[+13(7.10e-05)]_32_\
  4537. [+12(9.04e-07)]_27_[+5(1.42e-05)]_3_[+12(6.46e-05)]_50_[-20(6.76e-05)]_31_\
  4538. [-13(8.49e-08)]_40_[-14(5.11e-05)]_13_[-22(2.95e-05)]_24_[-19(2.74e-05)]_\
  4539. 28_[+1(5.67e-05)]_69_[-2(7.55e-05)]_190_[-19(5.41e-05)]_18_[-15(7.23e-07)]_\
  4540. 65_[+13(1.31e-05)]_97_[-11(3.58e-06)]_14_[+18(2.87e-06)]_46_\
  4541. [+10(4.79e-09)]_82_[-4(4.09e-05)]_102_[-23(3.05e-05)]_172_[+5(7.32e-09)]_\
  4542. 84_[+22(1.87e-09)]_73_[+8(6.21e-05)]_91_[+21(8.34e-06)]_821_[-7(7.82e-12)]_\
  4543. 107_[-7(5.07e-05)]_349_[+17(6.56e-05)]_20_[-19(1.52e-05)]_203_\
  4544. [-13(1.42e-05)]_129
  4545. Htr6 1.98e-275 9_[-12(3.27e-05)]_42_\
  4546. [-13(1.34e-06)]_57_[-15(4.77e-08)]_42_[+13(9.80e-06)]_3_[+13(3.17e-05)]_34_\
  4547. [-21(7.74e-06)]_44_[-23(6.14e-05)]_119_[-12(1.51e-05)]_[+3(5.43e-07)]_159_\
  4548. [+24(4.10e-13)]_68_[-19(2.93e-06)]_32_[-8(6.31e-05)]_1_[-20(9.18e-06)]_2_\
  4549. [+10(7.66e-18)]_20_[-11(1.09e-08)]_4_[-8(2.57e-06)]_61_[+5(9.21e-06)]_51_\
  4550. [-5(4.05e-05)]_35_[+23(4.14e-06)]_93_[+23(7.24e-05)]_1_[+12(1.53e-05)]_36_\
  4551. [-12(8.46e-05)]_136_[-23(7.35e-05)]_26_[+3(3.94e-08)]_149_[+14(5.19e-07)]_\
  4552. 3_[+10(9.49e-05)]_11_[+9(1.25e-05)]_75_[-6(7.08e-05)]_106_[+14(2.41e-05)]_\
  4553. 66_[+7(4.87e-05)]_29_[+7(1.94e-06)]_3_[-13(4.41e-05)]_63_[+4(1.03e-05)]_82_\
  4554. [+4(2.88e-14)]_33_[+14(7.41e-15)]_4_[+19(1.11e-05)]_262_[-6(3.08e-08)]_80_\
  4555. [+2(4.41e-07)]_1_[-25(6.48e-05)]_[-2(3.44e-21)]_33_[+18(2.40e-07)]_141_\
  4556. [-1(1.05e-06)]_20_[+22(4.57e-05)]_47_[-19(1.86e-07)]_114_[-22(8.76e-05)]_\
  4557. 164_[+15(1.18e-25)]_2_[+14(3.02e-22)]_69_[+25(2.57e-09)]_3_[-1(2.17e-29)]_\
  4558. 36_[+16(1.82e-05)]_11_[-8(1.88e-05)]_69_[+5(3.41e-05)]_87_[+19(9.68e-05)]_\
  4559. 98_[-6(3.65e-05)]_2_[-8(1.32e-05)]_2_[+13(1.59e-05)]_18_[+17(5.34e-15)]_\
  4560. 186_[-21(5.96e-05)]_106_[+5(1.19e-05)]_15_[+13(1.89e-05)]_156_\
  4561. [+5(2.36e-05)]_83_[-4(1.31e-05)]_2_[-8(8.69e-06)]_49_[+17(2.99e-05)]_25_\
  4562. [+19(1.70e-05)]_22_[+4(5.04e-06)]_2_[+14(9.55e-14)]_58_[+1(2.72e-07)]_37_\
  4563. [+23(2.09e-06)]_8_[+6(5.17e-12)]_91_[+1(1.88e-05)]_67_[-14(4.73e-11)]_33_\
  4564. [-4(3.80e-12)]_14_[+12(6.78e-05)]_68_[+3(2.40e-06)]_25_[+16(2.87e-06)]_14_\
  4565. [+7(1.89e-06)]_72_[-6(2.78e-05)]_56_[+8(2.57e-06)]_53_[-15(2.65e-05)]_16_\
  4566. [+8(4.98e-07)]_41_[+8(9.36e-06)]_53_[-24(4.60e-06)]_17_[-8(1.01e-06)]_8_\
  4567. [+3(5.91e-10)]_3_[+3(9.93e-07)]_31_[+19(5.82e-07)]_40_[-24(7.99e-05)]_16_\
  4568. [-12(4.14e-07)]_368_[-21(5.05e-06)]_1_[+4(1.77e-23)]_29_[+14(1.50e-11)]_12_\
  4569. [+25(7.11e-05)]_89_[+14(7.76e-05)]_78_[+25(9.93e-05)]_89_[+23(1.31e-19)]_7_\
  4570. [+6(6.63e-26)]_14_[+1(9.93e-09)]_87_[-18(1.72e-23)]_81_[-19(3.97e-05)]_84_\
  4571. [+10(1.18e-05)]_82_[+13(3.00e-05)]_167_[+16(1.49e-21)]_238_[+14(3.16e-06)]_\
  4572. 76_[-23(6.04e-06)]_22_[+7(3.60e-13)]_92_[+4(5.75e-10)]_39_[+9(6.16e-18)]_\
  4573. 78_[+4(3.64e-05)]_28_[-17(6.56e-05)]_61_[+12(5.46e-05)]_25_[+3(5.15e-19)]_\
  4574. 11_[+3(5.15e-19)]_6_[-8(8.09e-09)]_[+3(2.69e-12)]_39_[-19(7.72e-05)]_8_\
  4575. [+3(2.14e-05)]_6_[+2(5.33e-06)]_54_[+9(2.15e-05)]_14_[-5(4.24e-06)]_8_\
  4576. [+16(6.73e-05)]_73_[+3(4.83e-05)]_62_[-14(1.13e-08)]_32_[+8(5.62e-05)]_6_\
  4577. [+16(1.15e-05)]_15_[-24(1.41e-05)]_38_[-9(1.09e-05)]_1_[+7(2.32e-05)]_77_\
  4578. [-11(3.80e-05)]_86_[+5(1.46e-06)]_16_[-13(3.05e-05)]_27_[-7(4.97e-05)]_61_\
  4579. [+16(4.52e-05)]_48_[-19(2.26e-05)]_36_[+3(5.98e-06)]_[-8(8.69e-06)]_18_\
  4580. [+5(3.21e-05)]_5_[-8(4.89e-05)]_82_[+3(4.25e-06)]_50_[-20(3.57e-18)]_8_\
  4581. [+14(2.57e-10)]_138_[+15(2.69e-05)]_68_[-21(8.13e-06)]_154_[+10(2.91e-05)]_\
  4582. 284_[+5(3.62e-09)]_16_[-17(2.18e-05)]_5_[+21(2.86e-05)]_6_[+21(2.28e-07)]_\
  4583. 16_[+25(4.58e-06)]_116_[+22(9.03e-17)]_54_[-12(2.83e-18)]_51_\
  4584. [+13(9.77e-07)]_27_[-2(5.31e-05)]_91_[-5(3.59e-05)]_19_[+24(4.71e-05)]_8_\
  4585. [-16(9.81e-05)]_19_[+23(9.51e-05)]_[-19(4.70e-12)]_135_[-20(3.00e-05)]_108_\
  4586. [-6(2.00e-05)]_36_[-6(5.05e-06)]_6_[+16(2.15e-07)]_62_[-21(8.31e-08)]_\
  4587. [+3(9.83e-12)]_22_[+4(6.13e-06)]_1_[+14(2.39e-11)]_26_[-19(8.39e-05)]_122_\
  4588. [+13(3.35e-05)]_149_[-8(4.02e-06)]_15_[+8(6.63e-05)]_37_[+12(1.16e-05)]_15_\
  4589. [-6(1.42e-05)]_12_[-16(1.47e-05)]_6_[-12(6.96e-05)]_33_[-8(6.74e-05)]_40
  4590. Mchr1 1.44e-141 42_[+7(9.98e-11)]_21_\
  4591. [-13(7.86e-15)]_65_[-13(4.41e-06)]_34_[+6(7.72e-05)]_183_[-3(3.52e-07)]_2_\
  4592. [-3(2.43e-05)]_29_[-9(2.77e-05)]_[+8(1.92e-06)]_41_[-16(4.83e-05)]_14_\
  4593. [+5(1.32e-05)]_98_[-3(4.46e-14)]_53_[-14(7.94e-05)]_35_[+19(1.11e-05)]_85_\
  4594. [-1(6.50e-31)]_1_[-25(7.43e-05)]_188_[-3(6.47e-06)]_45_[-13(6.62e-05)]_25_\
  4595. [-21(1.83e-10)]_65_[+24(1.21e-14)]_44_[+17(1.25e-19)]_54_[+11(1.32e-05)]_\
  4596. 26_[+10(1.35e-19)]_31_[+17(2.58e-05)]_45_[-19(3.90e-05)]_50_[+3(1.88e-05)]_\
  4597. 97_[+5(1.40e-08)]_25_[+19(8.39e-05)]_27_[+22(3.77e-15)]_97_[+8(2.11e-05)]_\
  4598. 1_[-12(1.47e-05)]_20_[-13(4.57e-05)]_45_[-9(2.93e-05)]_15_[+21(3.56e-05)]_\
  4599. [+2(9.96e-15)]_167_[-12(3.02e-05)]_42_[+16(1.94e-05)]_242_[-7(3.23e-05)]_6
  4600. Sstr3 5.24e-226 21_[-2(9.46e-05)]_33_[+7(5.90e-14)]_\
  4601. 5_[-19(1.03e-05)]_5_[-3(2.26e-06)]_98_[-9(9.92e-15)]_6_[-4(1.43e-05)]_14_\
  4602. [-19(2.38e-06)]_83_[+23(7.35e-05)]_84_[-13(1.45e-05)]_38_[-3(6.52e-07)]_18_\
  4603. [+20(9.00e-06)]_57_[+5(1.91e-05)]_16_[+8(2.72e-05)]_7_[+11(5.89e-05)]_17_\
  4604. [-19(3.51e-06)]_39_[-5(6.63e-05)]_41_[-12(5.65e-06)]_54_[-3(9.55e-05)]_33_\
  4605. [-5(6.03e-06)]_31_[-10(3.68e-05)]_36_[+16(9.13e-05)]_61_[-13(3.64e-06)]_40_\
  4606. [-7(3.70e-05)]_40_[-5(7.83e-06)]_73_[+13(3.00e-05)]_182_[-9(4.30e-05)]_43_\
  4607. [-21(8.73e-05)]_24_[-21(7.86e-05)]_104_[+3(1.81e-05)]_84_[-21(2.45e-05)]_\
  4608. 22_[-21(2.05e-06)]_7_[-21(3.28e-06)]_23_[-25(3.77e-05)]_1_[-21(4.02e-06)]_\
  4609. 43_[-21(2.45e-05)]_3_[-21(6.35e-05)]_71_[+3(2.97e-05)]_117_[-4(6.24e-06)]_\
  4610. 2_[-24(9.56e-05)]_2_[+4(2.71e-05)]_97_[+13(6.56e-06)]_34_[-21(7.37e-05)]_\
  4611. 99_[+19(5.66e-05)]_35_[-11(5.89e-05)]_71_[+1(3.97e-06)]_52_[+8(1.96e-05)]_\
  4612. 56_[+19(1.29e-10)]_154_[-18(6.28e-05)]_33_[+20(4.35e-05)]_61_\
  4613. [-12(1.94e-06)]_2_[-12(3.52e-06)]_26_[+13(4.18e-07)]_66_[-8(1.38e-05)]_73_\
  4614. [-12(7.25e-07)]_2_[-16(9.49e-06)]_9_[-12(7.06e-18)]_60_[+3(1.98e-16)]_30_\
  4615. [+3(1.83e-07)]_23_[+13(7.80e-19)]_25_[-21(2.28e-06)]_78_[-12(1.14e-06)]_53_\
  4616. [+12(3.52e-06)]_50_[-9(3.10e-05)]_1_[+24(6.80e-05)]_1_[+21(2.68e-05)]_89_\
  4617. [-9(1.05e-05)]_12_[+9(3.27e-05)]_90_[+19(7.56e-05)]_125_[-13(2.53e-05)]_48_\
  4618. [-19(4.34e-05)]_7_[+16(1.33e-17)]_17_[-20(9.17e-13)]_25_[+4(2.58e-05)]_31_\
  4619. [+22(3.27e-06)]_78_[-6(4.84e-05)]_18_[-8(9.19e-06)]_81_[+19(8.56e-06)]_136_\
  4620. [-5(5.86e-06)]_21_[+2(2.85e-19)]_2_[+1(2.61e-29)]_5_[+7(7.10e-05)]_16_\
  4621. [-4(6.47e-06)]_21_[+9(8.32e-06)]_80_[+19(4.19e-06)]_49_[+17(8.71e-05)]_126_\
  4622. [-17(8.33e-06)]_106_[-15(8.21e-05)]_79_[+14(4.91e-05)]_42_[+21(5.59e-05)]_\
  4623. [-2(4.01e-05)]_47_[+13(5.86e-05)]_216_[+12(5.05e-05)]_12_[+12(2.57e-05)]_\
  4624. 47_[+18(2.01e-05)]_38_[+24(7.26e-05)]_8_[+8(3.18e-06)]_11_[+20(3.06e-05)]_\
  4625. 48_[-12(3.02e-05)]_65_[+15(2.88e-17)]_[-25(1.62e-05)]_30_[-15(7.61e-06)]_\
  4626. 106_[+25(1.76e-09)]_115_[-4(2.97e-05)]_41_[+11(1.16e-05)]_83_\
  4627. [+11(5.98e-06)]_42_[+24(7.19e-18)]_35_[+17(9.67e-17)]_114_[+10(2.83e-20)]_\
  4628. 2_[+13(6.84e-06)]_16_[-11(9.25e-19)]_94_[+5(3.83e-05)]_28_[+2(4.07e-05)]_\
  4629. 36_[+5(9.06e-23)]_17_[+5(4.24e-06)]_9_[+22(3.36e-20)]_89_[-3(2.83e-09)]_9_\
  4630. [+21(2.03e-15)]_94_[-5(4.63e-06)]_50_[-18(8.09e-08)]_11_[-11(2.32e-06)]_63_\
  4631. [-20(9.48e-05)]_262_[-6(2.57e-05)]_46_[+6(2.70e-05)]_79_[+24(5.04e-05)]_18_\
  4632. [-19(7.53e-07)]_117_[+8(6.87e-14)]_17_[-6(4.25e-21)]_79_[+23(4.09e-05)]_\
  4633. 146_[-20(2.02e-05)]_55_[+19(5.72e-05)]_24_[-14(5.46e-05)]_22_\
  4634. [-21(9.38e-07)]_20_[+18(2.48e-05)]_114_[-24(7.02e-05)]_99_[+21(7.86e-05)]_\
  4635. 11_[+21(3.64e-05)]_9_[+3(1.69e-05)]_60_[+8(1.71e-05)]_101_[+12(9.42e-06)]_\
  4636. 52
  4637. Npy2r 8.93e-187 266_[-4(5.49e-05)]_100_\
  4638. [+18(1.70e-20)]_54_[+13(1.02e-12)]_14_[-13(8.14e-05)]_75_[+12(1.35e-05)]_4_\
  4639. [-9(9.24e-05)]_28_[-21(1.63e-07)]_54_[+9(7.27e-14)]_8_[-10(8.95e-05)]_17_\
  4640. [+3(6.99e-06)]_45_[-20(6.20e-05)]_55_[-20(3.89e-05)]_1_[+12(3.32e-06)]_37_\
  4641. [-11(4.56e-05)]_236_[-19(2.05e-10)]_70_[+11(7.20e-05)]_155_[-3(1.78e-05)]_\
  4642. 93_[-3(3.61e-05)]_133_[+3(4.43e-06)]_23_[-8(4.54e-05)]_8_[+7(5.37e-05)]_\
  4643. 132_[-3(7.13e-06)]_150_[-16(8.65e-05)]_15_[+18(4.31e-05)]_2_[-3(5.78e-05)]_\
  4644. 24_[+1(2.62e-30)]_124_[-17(7.25e-05)]_378_[+20(4.67e-05)]_161_\
  4645. [-19(1.44e-05)]_97_[+19(2.88e-05)]_62_[+8(5.12e-06)]_[-8(9.02e-06)]_36_\
  4646. [+1(2.72e-11)]_29_[+7(6.01e-07)]_2_[+25(8.25e-06)]_42_[+1(1.31e-13)]_40_\
  4647. [+1(1.63e-06)]_106_[+4(4.62e-05)]_53_[+15(1.66e-05)]_52_[-13(1.97e-05)]_29_\
  4648. [+8(3.38e-07)]_128_[+25(4.47e-05)]_206_[+14(6.17e-05)]_3_[-3(2.05e-07)]_83_\
  4649. [+8(9.81e-14)]_214_[+3(1.19e-14)]_79_[+20(7.85e-14)]_128_[+7(3.98e-06)]_43_\
  4650. [-21(8.76e-11)]_184_[+15(1.23e-18)]_28_[+25(9.93e-05)]_11_[+1(3.88e-23)]_1_\
  4651. [+25(2.61e-07)]_5_[+1(3.69e-12)]_32_[+19(1.87e-05)]_97_[-10(7.63e-05)]_2_\
  4652. [+14(5.23e-05)]_174_[-1(2.62e-30)]_[-1(3.15e-15)]_7_[-25(1.78e-07)]_3_\
  4653. [-25(2.61e-07)]_6_[-7(1.75e-10)]_5_[-14(5.34e-05)]_6_[-15(5.02e-17)]_76_\
  4654. [-23(1.52e-17)]_80_[+16(9.81e-05)]_450_[-10(7.47e-06)]_22_[-15(1.24e-05)]_\
  4655. 73_[+24(1.18e-18)]_35_[+17(1.72e-17)]_40_[+16(5.56e-06)]_36_\
  4656. [+10(2.30e-18)]_25_[+10(7.89e-07)]_46_[+12(4.56e-05)]_93_[+4(3.27e-05)]_46_\
  4657. [+5(6.09e-20)]_4_[-12(8.22e-05)]_34_[+22(8.37e-15)]_162_[-3(2.76e-05)]_104_\
  4658. [-3(3.55e-05)]_54_[+8(2.37e-06)]_52_[-5(1.37e-05)]_547_[-21(9.21e-06)]_511_\
  4659. [+17(1.51e-05)]_149_[+5(2.75e-05)]_95_[+17(9.92e-05)]_108
  4660. --------------------------------------------------------------------------------
  4661.  
  4662. ********************************************************************************
  4663.  
  4664.  
  4665. ********************************************************************************
  4666. Stopped because requested number of motifs (25) found.
  4667. ********************************************************************************
  4668.  
  4669. CPU: node257
  4670.  
  4671. ********************************************************************************
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