Link- https://stackoverflow.com/questions/34199976/iis-config-error-this-configuration-section-cannot-be-used-at-this-path

Follow the below steps to unlock the handlers at the parent level:

1) In the connections tree(in IIS), go to your server node and then to your website.

2) For the website, in the right window you will see configuration editor under Management.

3) Double click on the configuration editor.

4) In the window that opens, on top you will find a drop down for sections. Choose "system.webServer/handlers" from the drop down.

5) On the right side, there is another drop down. Choose "ApplicationHost.Config "

6) On the right most pane, you will find "Unlock Section" under "Section" heading. Click on that.

7) Once the handlers at the applicationHost is unlocked, your website should run fin