my.cnf for 48G Linode Fabric Percona 5.6

[mysql]

# CLIENT #
port				= 3306
socket				= /var/lib/mysql/mysql.sock

[mysqld]

# GENERAL #
user				= mysql
default-storage-engine		= InnoDB
socket				= /var/lib/mysql/mysql.sock
pid-file			= /var/lib/mysql/mysql.pid

#Connection timeout
wait_timeout			= 600
interactive_timeout		= 600

# MyISAM #
key-buffer-size			= 32M
myisam-recover			= FORCE,BACKUP

# SAFETY #
max-allowed-packet		= 16M
max-connect-errors		= 1000000
sysdate-is-now			= 1
innodb				= FORCE

# DATA STORAGE #
datadir				= /var/lib/mysql/

# BINARY LOGGING #
log-bin				= /var/lib/mysql/mysql-bin
expire-logs-days		= 14
sync-binlog			= 1

# REPLICATION #
server-id			= 34
read-only			= 0
#skip-slave-start		= 1
log-slave-updates		= 1
relay-log			= /var/lib/mysql/relay-bin
slave-net-timeout		= 60
sync-master-info		= 1
sync-relay-log			= 1
sync-relay-log-info		= 1

#temporary for fabric prep dat acleanup
#slave-skip-errors		= 1032

#binlog-do-db			= serpsalpha
binlog-format			= 'ROW'

#Fabric:
#skip-slave-start (=0), binlog-do-db (empty), & binlog-format (ROW) above are changed for Fabric.
#additionally, sync-master-info must be on for Fabric, and the following:
gtid-mode			= 'ON'
enforce-gtid-consistency	= 'ON'
simplified_binlog_gtid_recovery	= 'ON'	#Note: this variable has been changing name a lot. It can fail under special circumstances. See details at http://v.gd/2XcOhf
master-info-repository		= TABLE
relay-log-info-repository	= TABLE
#report-host=	might want to set this for fabric
#report-port	#no need to set, as it's reported correctly as of 5.5 or 5.6...

# CACHES AND LIMITS #
tmp-table-size			= 32M
max-heap-table-size		= 32M
query-cache-type		= 0
query-cache-size		= 0
max-connections			= 500
thread-cache-size		= 50
open-files-limit		= 65535
table-definition-cache		= 1024
table-open-cache		= 55

# INNODB #
innodb-flush-method		= O_DIRECT
innodb-log-files-in-group	= 2
innodb-log-file-size		= 512M
innodb-flush-log-at-trx-commit	= 2
innodb-file-per-table		= 1
innodb-buffer-pool-size		= 40G
innodb-rollback-on-timeout	= ON
transaction-isolation		= READ-COMMITTED
low-priority-updates		= 1

# LOGGING #
log-error			= /var/log/mysql/mysql-error.log
log-queries-not-using-indexes	= 0
slow-query-log			= 1
slow-query-log-file		= /var/log/mysql/mysql-slow.log
long-query-time			= 10