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MATLAB. Inverse crop images.
I=imread('img_9.tif');
I2=imcrop(I,[60,50,85,85]);
n_big=size(I);
n_small=size(I2);

for j1=1:(n_big(1)-n_small(1))
for j2=1:(n_big(2)-n_small(2))
    Itest=I(j1:j1+n_small(1)-1,j2:j2+n_small(2)-1,:);
    if ( Itest == I2)
        I(j1:j1+n_small(1)-1,j2:j2+n_small(2)-1,:) = zeros(n_small(1),n_small(2),3);
    end
end
end

figure(1);
imshow(I);
figure(2);
imshow(I2);