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Is it possible to configure Autofac to work with ASP.NET MVC and ASP.NET Web Api
// Set the dependency resolver implementation.
GlobalConfiguration.Configuration.DependencyResolver = resolver;

var builder = new ContainerBuilder();

// Add your registrations

var container = builder.Build();

// Set the dependency resolver for Web API.
var webApiResolver = new AutofacWebApiDependencyResolver(container);
GlobalConfiguration.Configuration.DependencyResolver = webApiResolver;

// Set the dependency resolver for MVC.
var mvcResolver = new AutofacDependencyResolver(container);
DependencyResolver.SetResolver(mvcResolver);

internal class AutofacWebAPI {

    public static void Initialize(HttpConfiguration config) {

        config.DependencyResolver = new AutofacWebApiDependencyResolver(
            RegisterServices(new ContainerBuilder())
        );
    }

    private static IContainer RegisterServices(ContainerBuilder builder) {

        builder.RegisterAssemblyTypes(Assembly.GetExecutingAssembly()).PropertiesAutowired();

        //deal with your dependencies here
        builder.RegisterType<CarsService>().As<ICarsService>();
        builder.RegisterType<CarsCountService>().As<ICarsCountService>();

        return builder.Build();
    }
}

AutofacWebAPI.Initialize(GlobalConfiguration.Configuration);