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Simple cross-platform process to process communication in Mono?
public static IList Processes()
    {
        IList<Process> processes = new List<Process>();
        foreach (System.Diagnostics.Process process in System.Diagnostics.Process.GetProcesses())
        {
            Process p = new Process();
            p.Pid = process.Id;
            p.Name = process.ProcessName;

            processes.Add(p);
        }
        return processes;
    }

(mutex, locked) = System.Threading.Mutex(True, "MyApp/%s" % System.Environment.UserName, None)
if locked:
    watcher = System.IO.FileSystemWatcher()
    watcher.Path = path_to_user_dir
    watcher.Filter = "messages"
    watcher.NotifyFilter = System.IO.NotifyFilters.LastWrite
    watcher.Changed += handleMessages
    watcher.EnableRaisingEvents = True
else:
    messages = os.path.join(path_to_user_dir, "messages")
    fp = file(messages, "a")
    fp.write(command)
    fp.close()
    sys.exit(0)