Option A
-->Option B
-->Option C
---->Option D

Private Sub cmbProductCategory_TextChanged(sender As Object, e As    EventArgs) Handles cmbProductCategory.TextChanged
    If Not String.IsNullOrWhiteSpace(cmbProductCategory.Text.Trim()) Then
        cmbProductCategory.Text.ToString().Replace("--", String.Empty).Replace(">", String.Empty).Trim()
    End If
End Sub'